About: Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

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About: Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions Goto Sponge NotDistinct Permalink

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description	artículu científicu espublizáu en 2002 (ast) vědecký článek publikovaný v roce 2002 (cs) наукова стаття, опублікована в лютому 2002 (uk) 2002 թվականի փետրվարին հրատարակված գիտական հոդված (hy) 2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած (hyw) article scientifique publié en 2002 (fr) vedecký článok (publikovaný 2002/02/04) (sk) wetenschappelijk artikel (gepubliceerd op 2002/02/04) (nl) im Februar 2002 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en) مقالة علمية (نشرت في 4-2-2002) (ar)
publication date	wds:Q28513507-89488896-3E06-4984-98E8-F5087CE8E728
publication date	2002-02-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28513507-5F6C09FC-312C-43C6-9EF7-10B5172FD835
language of work or name	English
cites work	wds:Q28513507-07F7BD3F-1B71-4F80-A0CA-7B1B54635575 wds:Q28513507-1F91C21B-3C1B-4348-891B-FA42BE4BC199 wds:Q28513507-27A1F12C-79CD-417B-AA3C-5A58B6746609 wds:Q28513507-2E929498-35D0-4130-AF50-4EAC7C373245 wds:Q28513507-3624B9AB-CF47-4451-B68B-7411B8B78E01 wds:Q28513507-567F78A3-F92C-4E72-89AE-2031B9C7F0FA wds:Q28513507-576D57CB-E21F-4F7A-8FE6-6E0C51BA5A5A wds:Q28513507-57F05397-04AE-48B0-84B4-D986A8E4899C wds:Q28513507-5B6F277B-A519-4C55-BFEB-D7BFF7D65468 wds:Q28513507-5E25E836-50EE-438A-86AE-68486070D67C wds:Q28513507-6611C0D2-E643-41FC-AE1F-13F31E9DB733 wds:Q28513507-6A5D12F8-FC31-4862-9D1F-F62F8EA4F565 wds:Q28513507-6C04E168-C083-48B7-B433-EA94C5D19D68 wds:Q28513507-6DC88F49-8EEB-4D68-8B01-F3EFA856844C wds:Q28513507-7BF247CA-FF8F-48C4-B96C-DEFB72EFA247 wds:Q28513507-9F61F342-183B-4481-BA39-8FB1BAA1E1E4 wds:Q28513507-AFB63C6B-FA93-46DE-935E-BC9BA910E754 wds:Q28513507-B175466B-1B36-49D7-A7F2-A94CCB325AAC wds:Q28513507-B30FE1E7-1C64-43CA-8EAD-1B3C9857FD78 wds:Q28513507-B3AF95CC-7415-4A6C-8DE4-CD2DB27A446B wds:Q28513507-B9BEC252-AF9F-44FB-9F3F-061FE93D258D wds:Q28513507-C22C0362-3C45-4973-8978-F9047588A168 wds:Q28513507-CBE2BFE3-A10B-4F64-B8D2-42871352BEC9 wds:Q28513507-D4719FE7-8417-4A7C-8E4C-4C6FBF797100 wds:Q28513507-DA543D62-7A52-496D-B123-B571272D9A35 wds:Q28513507-F2E79ACE-13C2-4A16-9852-1163E39FF0F6 wds:Q28513507-F7161DE3-E07E-4E8A-A993-F2B3D944A1E4
cites work	Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis Ku70 is required for late B cell development and immunoglobulin heavy chain class switching Ku80 is required for immunoglobulin isotype switching Molecular processes that regulate class switching DNA sequences at immunoglobulin switch region recombination sites Ig Sgamma3 DNA-specifc double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination Enhancement of MSH2-MSH3-mediated mismatch recognition by the yeast MLH1-PMS1 complex High affinity cooperative DNA binding by the yeast Mlh1-Pms1 heterodimer Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination 'Saccharomyces cerevisiae MSH2/6 complex interacts with Holliday junctions and facilitates their cleavage by phage resolution enzymes Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae Multiple functions of MutS- and MutL-related heterocomplexes Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2 Mismatch repair co-opted by hypermutation. Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity Mismatch repair proteins and mitotic genome stability Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern Severe attenuation of the B cell immune response in Msh2-deficient mice Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation. The liaison of isotype class switch and mismatch repair: an illegitimate affair
author name string	wds:Q28513507-286B6811-A4FF-44D4-B097-0A844329ADC4 wds:Q28513507-3207389D-DC4D-4032-8653-9B02017B164F
author name string	Janet Stavnezer Joycelyn Vardo
rdfs:label	Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (en) Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (nl) Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (ast)
skos:prefLabel	Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (en) Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (nl) Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (ast)
name	Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (en) Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (nl) Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (ast)
author	wds:Q28513507-79C98312-4AC2-4082-B6CB-B19BFF3B41B1
author	Carol E. Schrader
title	wds:Q28513507-492F83B7-9335-47D3-9C93-531C091079A9
title	Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (en)
page(s)	wds:Q28513507-AD8AE8B6-11AC-4EF1-9DFD-4BAE44F72FA9
page(s)	367-373
instance of	wds:Q28513507-13456BC4-1D13-4456-8EB9-178C8B1D04FE
instance of	scholarly article
main subject	wds:Q28513507-4DA78721-6DC9-4EAE-95FF-D8A9A098E573 wds:Q28513507-E7334E70-2016-4BBE-B74C-8F163FD4809E wds:Q28513507-EA6EC9AA-BB7D-4B5F-B1C7-93F141812EFA wds:Q28513507-FE2B22B6-AC09-4BD6-A374-AFD9831F468D
main subject	DNA mismatch repair MutL homolog 1 MutS homolog 2 Mismatch repair endonuclease PMS2
PubMed ID	wds:Q28513507-D95F141D-78A4-4EAF-9738-CA8B260E3A3A

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