About: From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific article published on 01 June 2006

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в травні 2006 (uk) im Mai 2006 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xunu de 2006 (ast) scientific article published on 01 June 2006 (en)
publication date	wds:Q63384400-F0EBDE60-404B-4CE1-8519-5901F9AFA0AE
publication date	2006-06-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q63384400-B606B468-44E1-486B-B3E6-1B3F378CA25A
language of work or name	English
cites work	wds:Q63384400-B4BC4176-CDB0-4F05-B908-270DFF84F1BA
cites work	Evidence that glucokinase regulatory protein is expressed and interacts with glucokinase in rat brain
author name string	wds:Q63384400-0B73252E-4504-4968-B38B-F6573C9F1AA4 wds:Q63384400-202A9A16-DADA-4E81-B378-AE9989A60B34 wds:Q63384400-3BE2B1CB-5482-4693-B354-BF054EE7866B wds:Q63384400-4403F1CF-0AFE-485E-A55F-8011824E197F wds:Q63384400-5CD870E7-9DA9-480D-9C4B-EBDDEF84CA31 wds:Q63384400-767C8E6D-C16B-4437-A9AC-BF35240EB4FF wds:Q63384400-856CAF9C-5CF9-402A-8D14-10A0D9D4C056 wds:Q63384400-C451F541-C254-418B-A16F-401CDDAA90E2 wds:Q63384400-EB13B826-74B0-486A-ADCC-E1C658910C92
author name string	Carol Buettger Franz M Matschinsky Yi Han Knut Dahl-Jørgensen Joseph Grimsby Rebecca Taub Jae Kwagh Stella Odili Dorothy Zelent
rdfs:label	From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation (en) From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation (nl)
skos:prefLabel	From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation (en) From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation (nl)
name	From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation (en) From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation (nl)
author	wds:Q63384400-336A2588-AA02-488C-B6D2-86920A9DD46B wds:Q63384400-36D49F20-4E1E-42FC-B83E-527EA449EA2E wds:Q63384400-3D02C29F-F484-4F59-96C3-672478DBFC14 wds:Q63384400-6ADCA453-8AF4-4DED-B971-E9C828C84E84 wds:Q63384400-A2051263-AF22-40C5-8B1F-FEFDA1EEACE2 wds:Q63384400-C2224A8D-F73E-40EA-A8A2-73B0586CC943 wds:Q63384400-CE43B7B0-061C-4BE3-BE9A-3F56091DE0B8 wds:Q63384400-F113795A-F5B9-406E-9BB9-7388B0E7E379
author	Charles A Stanley Graeme I. Bell Oddmund Søvik Pål R Njølstad Anders Molven Carine de Beaufort Jørn V Sagen Lise Bjørkhaug Gundersen
title	wds:Q63384400-DF5F2E4B-7964-40EB-B995-9F3817B0D5F3
title	From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation (en)
page(s)	wds:Q63384400-75859636-F947-4C13-89C5-F79A09F30394
page(s)	1713-1722
instance of	wds:Q63384400-B32BFA18-2412-4AE2-AED3-F4CD9EF44E4F
instance of	scholarly article
main subject	wds:Q63384400-516F477C-B88D-4B50-B664-4535BA873985
main subject	type 2 diabetes
PubMed ID	wds:Q63384400-AC57714D-0F25-40FC-A6A4-7B1BDB603041
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16731834
PubMed ID	16731834
published in	wds:Q63384400-5B784BA3-7F4B-4A35-A866-267B8D02A876
published in	Diabetes
issue	wds:Q63384400-304C3BF5-C63B-4152-82F1-40C8DDCFD463
volume	wds:Q63384400-9961C1B0-A032-4908-ABB2-800FF37C6C7B
issue	6
volume	55
DOI	wds:Q63384400-74792D21-56EB-4F54-8810-C96DF3B90151
DOI	http://dx.doi.org/10.2337/DB05-1513
DOI	10.2337/DB05-1513
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q63384400
is cites work of	Assessing the potential of glucokinase activators in diabetes therapy Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia Functional analysis of human glucokinase gene mutations causing MODY2: exploring the regulatory mechanisms of glucokinase activity Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions Glucokinase gene mutations: structural and genotype-phenotype analyses in MODY children from South Italy Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry. Functional characterization of MODY2 mutations highlights the importance of the fine-tuning of glucokinase and its role in glucose sensing Binding of ATP at the active site of human pancreatic glucokinase--nucleotide-induced conformational changes with possible implications for its kinetic cooperativity Genes related to diabetes may be associated with pancreatic cancer in a population-based case-control study in Minnesota Glucokinase activation repairs defective bioenergetics of islets of Langerhans isolated from type 2 diabetics Discovery of a novel site regulating glucokinase activity following characterization of a new mutation causing hyperinsulinemic hypoglycemia in humans Chronic ethanol consumption-induced pancreatic {beta}-cell dysfunction and apoptosis through glucokinase nitration and its down-regulation SUMOylation of pancreatic glucokinase regulates its cellular stability and activity Chronic alcohol consumption potentiates the development of diabetes through pancreatic β-cell dysfunction Homotropic allosteric regulation in monomeric mammalian glucokinase Insight into the biochemical characteristics of a novel glucokinase gene mutation. Probable Potential Role of Urate Transporter Genes in the Development of Metabolic Disorders. Identification and functional characterisation of novel glucokinase mutations causing maturity-onset diabetes of the young in Slovakia GCK-MODY in the US National Monogenic Diabetes Registry: frequently misdiagnosed and unnecessarily treated Phenotypic severity of homozygous GCK mutations causing neonatal or childhood-onset diabetes is primarily mediated through effects on protein stability The previously reported T342P GCK missense variant is not a pathogenic mutation causing MODY. Thermal stability of glucokinase (GK) as influenced by the substrate glucose, an allosteric glucokinase activator drug (GKA) and the osmolytes glycerol and urea Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators Mutational analysis of allosteric activation and inhibition of glucokinase Evidence-based tailoring of bioinformatics approaches to optimize methods that predict the effects of nonsynonymous amino acid substitutions in glucokinase.

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 182 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software