About: Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage

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About: Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage Goto Sponge NotDistinct Permalink

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scientific journal article

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rdf:type	Item
description	article scientifique publié en 2004 (fr) artículu científicu espublizáu en 2004 (ast) vědecký článek publikovaný v roce 2004 (cs) 2004 թվականի մայիսին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в травні 2004 (uk) 2004 թուականի Մայիսին հրատարակուած գիտական յօդուած (hyw) vedecký článok (publikovaný 2004/05/11) (sk) مقالة علمية (نشرت في 11-5-2004) (ar) wetenschappelijk artikel (gepubliceerd op 2004/05/11) (nl) scientific journal article (en) im Mai 2004 veröffentlicher wissenschaftlicher Artikel (de)
publication date	wds:Q28591999-3612FD6B-9484-4BB2-963B-AA52D1BA3795
publication date	2004-05-11 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28591999-6F339EB3-3E12-48A0-A48B-4C60CDCA467F
language of work or name	English
author name string	wds:Q28591999-1686CA09-7AD7-438B-9FED-299E6E5A9182 wds:Q28591999-5897580C-7CEC-4B34-9CCD-398B8E67A3B0 wds:Q28591999-6AC7078D-853D-49F9-A239-D01B3D85A646 wds:Q28591999-6B51AFF0-A20F-4772-80D7-45AAC6297627 wds:Q28591999-9211AB12-41C4-40C0-B3BD-296F0D22C282 wds:Q28591999-B6EB70B3-A2A4-4838-9A56-B06EF9762B50 wds:Q28591999-ECDA595D-B8BA-4E35-A6A9-38A581C92172
OpenCitations bibliographic resource ID	wds:Q28591999-86424EA5-B997-4ADB-82FD-822C5BAAC3EF
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/4880342
author name string	Pei Wang Hui Zheng Xuefeng Xia Margaret A. Goodell Xiaoli Chen Yibing Qyang Stuart M. Chambers
OpenCitations bibliographic resource ID	4880342
rdfs:label	Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage (en) Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage (nl) Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage (ast)
skos:prefLabel	Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage (en) Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage (nl) Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage (ast)
name	Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage (en) Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage (nl) Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage (ast)
title	wds:Q28591999-08DDAE73-8E93-4BCE-BDD6-A7B771EE6EBD
title	Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage (en)
page(s)	wds:Q28591999-F70E66D4-4733-4644-B92C-9EB57F20D3A6
page(s)	5352–5359
instance of	wds:Q28591999-A58BA81F-4C99-4471-A471-BBE8584F1222
instance of	scholarly article
main subject	wds:Q28591999-166425A2-91F8-4552-8E8D-E59EDEB5B359 wds:Q28591999-CAB3172B-D798-494E-B5BB-194D3E3753B0
main subject	Presenilin 1 Presenilin 2
PubMed ID	wds:Q28591999-2076DF21-FC1A-4DF9-88E1-CE823B51AB06
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15122901
PubMed ID	15122901
published in	wds:Q28591999-D41B538A-7C60-4A43-9B41-D4A559FA2121
published in	Biochemistry
issue	wds:Q28591999-D7E02237-68A5-4D11-832F-54256800F40E
volume	wds:Q28591999-6ED77E85-EA79-42FD-A265-ECB26679D166
issue	18
volume	43
DOI	wds:Q28591999-2EAF627F-BCF1-4031-8F8A-63D584A88B85
DOI	http://dx.doi.org/10.1021/BI049826U
DOI	10.1021/BI049826U
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28591999
is cites work of	Genetic dissection of gamma-secretase-dependent and -independent functions of presenilin in regulating neuronal cell cycle and cell death Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease Partial loss of presenilin impairs age-dependent neuronal survival in the cerebral cortex Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity Notch signaling in the regulation of stem cell self-renewal and differentiation Hematopoietic cytokine-induced transcriptional regulation and Notch signaling as modulators of MDSC expansion Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window An overview of notch signaling in adult tissue renewal and maintenance Identification of gamma-secretase inhibitor potency determinants on presenilin. Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities Defects of immune regulation in the presenilin-1 mutant knockin mouse. Deletion of presenilin 1 hydrophilic loop sequence leads to impaired gamma-secretase activity and exacerbated amyloid pathology. Targeting Notch to overcome radiation resistance Regulation of tyrosinase trafficking and processing by presenilins: partial loss of function by familial Alzheimer's disease mutation The γ-secretase complex: from structure to function Mutational re-modeling of di-aspartyl intramembrane proteases: uncoupling physiologically-relevant activities from those associated with Alzheimer's disease. Myeloproliferation and hematopoietic stem cell dysfunction due to defective Notch receptor modification by O-fucose glycans The emergence of ADAM10 as a regulator of lymphocyte development and autoimmunity ADAM10 overexpression shifts lympho- and myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease The Notch2-Jagged1 interaction mediates stem cell factor signaling in erythropoiesis Notch Signaling in the Regulation of Hematopoietic Stem Cell Defective signal transduction in B lymphocytes lacking presenilin proteins Loss of Presenilin 2 Function Is Associated with Defective LPS-Mediated Innate Immune Responsiveness. Efficient production of a mature and functional gamma secretase protease
is cites work of	wds:Q34677532-BF17ED01-7382-4E94-83F2-0E97C1D6B85A wds:Q47155049-F42A2180-790D-48B3-AF78-0D3441284E91 wds:Q37993403-EF6C9107-70F2-46C6-9828-010710C7DF05 wds:Q44963738-DE81DAD7-4B5A-47F4-A6F7-92A5144B91B0 wds:Q37261981-B6B01C15-6B79-4D8C-B922-838271E1035A wds:Q28588005-FE450138-A3CE-4D38-8A5F-99D1599C5F81 wds:Q28588759-3366BEDE-942E-45A4-98B6-E13C7C6EA62A wds:Q27333237-3F974935-0F8E-409A-A431-27CBA916AC57

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