About: Structure of replicating SARS-CoV-2 polymerase

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scientific article published on 21 May 2020

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rdf:type	Item
description	artículu científicu espublizáu en mayu de 2020 (ast) im Mai 2020 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована 21 травня 2020 (uk) scientific article published on 21 May 2020 (en)
publication date	wds:Q95301171-688B54C7-1631-4C51-A370-6A7235E2B006
publication date	2020-05-21 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q95301171-0824EA9A-08C0-47CA-91CD-D15BF47A317B
language of work or name	English
cites work	wds:Q95301171-03C5B82D-B6C8-458D-B95D-475D37E679C8 wds:Q95301171-0D6F56F6-8AE8-4842-AA87-63BADBC8699F wds:Q95301171-1C10FEDC-6B5B-43EB-BE6A-BB7732FBE223 wds:Q95301171-2BD39BCF-C035-47EF-9B3E-8A9E908903E5 wds:Q95301171-2FC278BA-7623-416A-8389-39CB343409AE wds:Q95301171-37675E53-AD4F-4D07-BFA7-6306704ADC4A wds:Q95301171-462DBCEF-C1E2-4FBB-B070-218839FD6735 wds:Q95301171-4A5A2B96-0262-405B-BFAA-A1FA65192D9F wds:Q95301171-4CCE0FA3-EADC-46BE-8997-D4467A0AA9D5 wds:Q95301171-52C83EC6-AEBA-4867-BC5C-21101A6634F4 wds:Q95301171-5932BAD3-55EB-40DC-B17C-03246A2BFC27 wds:Q95301171-5C4155CF-6EC6-4E76-90C2-B9AFD589A783 wds:Q95301171-5F667BC0-7D68-46E8-84A7-A77FD2EEBE09 wds:Q95301171-5FCE121D-437B-461A-AE00-F3EDC49D4870 wds:Q95301171-66DFB01E-3D9F-4454-9981-7AC7E893C297 wds:Q95301171-6FC546E3-57F0-4476-8599-2804F609BC68 wds:Q95301171-714106A8-49D0-42F5-A29D-675FC1F7A0F9 wds:Q95301171-76AE6505-68F2-451A-AE22-5822536CCB1A wds:Q95301171-827C3080-38FF-4596-B54F-F23BCFE4F3B6 wds:Q95301171-919D5A53-77E1-44DB-AEBC-E87F3343BD3E wds:Q95301171-9608FE80-4311-4026-BAE7-D1BBE640348F wds:Q95301171-96C5C06D-C8D3-4D5C-8ED3-C729C5E574B1 wds:Q95301171-989AEA48-6579-42A3-AD73-85408A9B69DF wds:Q95301171-9BC711AA-5905-4E08-B37D-DD4BE4D706FE wds:Q95301171-A4BC784D-5A67-498C-A416-374D1F8CA091 wds:Q95301171-A8087B28-6F43-45D2-93A8-F80AA7DF64DC wds:Q95301171-BCDC1ABA-7E42-4F74-940E-65757056E743 wds:Q95301171-BCF9F015-DC06-4160-9602-E34904A14410 wds:Q95301171-D3507940-5815-47AA-8795-CF97F0FA364E wds:Q95301171-D3CBC22C-4AFC-43EC-9B5F-76C35CC871AC wds:Q95301171-DE772120-7C1A-419A-A914-1ABFB56F2558 wds:Q95301171-E3BFFE95-7D34-40EA-86D7-6DDB70A179AC wds:Q95301171-EA1B6C5C-6A24-4224-B0F5-BC30DD2EFEDD wds:Q95301171-EB37D8D3-0F91-4980-B166-0926CAD192F3
cites work	Features and development of Coot SARS-CoV ORF1b-encoded nonstructural proteins 12-16: replicative enzymes as antiviral targets. Automated electron microscope tomography using robust prediction of specimen movements RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase PCNA, the maestro of the replication fork Biochemical characterization of a recombinant SARS coronavirus nsp12 RNA-dependent RNA polymerase capable of copying viral RNA templates cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses Insights into SARS-CoV transcription and replication from the structure of the nsp7-nsp8 hexadecamer Nonstructural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer That Exhibits Primer-Independent RNA Polymerase Activity One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site Enhancing UCSF Chimera through web services Nidovirus RNA polymerases: Complex enzymes handling exceptional RNA genomes The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. Real-space refinement in PHENIX for cryo-EM and crystallography A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. A pneumonia outbreak associated with a new coronavirus of probable bat origin A new coronavirus associated with human respiratory disease in China Real-time cryo-electron microscopy data preprocessing with Warp Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir Structure of the RNA-dependent RNA polymerase from COVID-19 virus The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir Architecture and RNA binding of the human negative elongation factor. Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors Race to find COVID-19 treatments accelerates Structural Basis for the Inhibition of the RNA-Dependent RNA Polymerase from SARS-CoV-2 by Remdesivir Hopes rise for coronavirus drug remdesivir Nucleosides for the treatment of respiratory RNA virus infections.
author name string	wds:Q95301171-D01A8C06-5201-4B95-B374-69C4DEFAB80E
author name string	Christian Dienemann
rdfs:label	Structure of replicating SARS-CoV-2 polymerase (en)
skos:prefLabel	Structure of replicating SARS-CoV-2 polymerase (en)
name	Structure of replicating SARS-CoV-2 polymerase (en)
author	wds:Q95301171-11D1370A-80B4-403B-84E6-9A40580E54D6 wds:Q95301171-40026938-637E-42FA-9D5E-059C3211C72C wds:Q95301171-9584ACB3-A540-4BFE-B3D1-15D3BF0ED3CF wds:Q95301171-CFF6B580-86A4-452B-9912-7BC6526DACB0 wds:Q95301171-EF5E6B92-C472-47FF-9E8C-9B38DD75761F
author	Patrick Cramer Lucas Farnung Hauke S Hillen Dimitry Tegunov Goran Kokic
title	wds:Q95301171-71C710C4-B3AD-4E95-BD19-6C2C743C61DB
title	Structure of replicating SARS-CoV-2 polymerase (en)
instance of	wds:Q95301171-582302DC-E986-4708-A3D4-F929A5D7D934
instance of	scholarly article
main subject	wds:Q95301171-13f7ce5e-474c-d2d8-1756-9bc86a52b7cd wds:Q95301171-5E46E2DE-E77D-4E30-9594-6033198F4BE1 wds:Q95301171-68628417-4391-6a28-e83a-f27b9d829e69 wds:Q95301171-7076f7ab-4f1e-1a21-1751-e72bca34f853

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