About: Physiologically Based Pharmacokinetic Modeling to Supplement Nilotinib Pharmacokinetics and Confirm Dose Selection in Pediatric Patients

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scientific article published on 02 February 2019

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rdf:type	Item
description	wetenschappelijk artikel (nl) artículu científicu espublizáu en febreru de 2019 (ast) наукова стаття, опублікована в лютому 2019 (uk) scientific article published on 02 February 2019 (en)
publication date	wds:Q91354180-F527D386-ED55-4014-A821-DE942573D5EA
publication date	2019-02-02 00:00:00Z (xsd:dateTime)
cites work	wds:Q91354180-10DB6DAE-F00F-4049-A989-7ACD5FB720CE wds:Q91354180-1E3BE506-991E-4400-A7B1-19A530EFDB7D wds:Q91354180-240322E6-2423-43A2-A655-CD75415C5D0E wds:Q91354180-5D76E2FC-1151-4662-A5E6-DD0A3540BC94 wds:Q91354180-624347F3-0D25-4CB4-9C24-BC0C5A30FEA3 wds:Q91354180-6857D57B-7521-4832-AD79-BC9D2F7726A2 wds:Q91354180-79C6C0B3-4F34-4E63-9B82-8DF0E8DAF433 wds:Q91354180-7F11B20A-F962-4085-9D22-04488FB6E610 wds:Q91354180-9103F27B-2812-4EC5-A577-6E421B7897E5 wds:Q91354180-A1B038FF-5F93-4869-89D8-AD93668CD8AC wds:Q91354180-B17B95F0-83C7-4BA6-B876-07A253D97DE7 wds:Q91354180-B29C0BCD-6860-4D9C-BAA3-B539CD68B493 wds:Q91354180-B8D8CC15-D3E4-4A88-B701-C9A95C78FD81 wds:Q91354180-EC4285BC-00DA-4AFA-8E87-A39F71EB9502 wds:Q91354180-EEC4C03D-85F5-4264-A992-A425488D3B77 wds:Q91354180-F9988F9D-CE97-4B13-A765-B35FDEEDF574
cites work	Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development Changes in individual drug-independent system parameters during virtual paediatric pharmacokinetic trials: introducing time-varying physiology into a paediatric PBPK model Long-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial Clinical pharmacokinetics of the BCR-ABL tyrosine kinase inhibitor nilotinib Effect of cardiopulmonary bypass on fentanyl distribution and elimination. Prediction of drug clearance in children Application of Physiologically Based Pharmacokinetic (PBPK) Modeling to Support Dose Selection: Report of an FDA Public Workshop on PBPK. Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase Meta-analysis of hepatic cytochrome P450 ontogeny to underwrite the prediction of pediatric pharmacokinetics using physiologically based pharmacokinetic modeling A pharmacokinetic study of midazolam in paediatric patients undergoing cardiac surgery. A Physiologically Based Pharmacokinetic Model to Describe Artemether Pharmacokinetics in Adult and Pediatric Patients Clinical Pharmacokinetic and Pharmacodynamic Overview of Nilotinib, a Selective Tyrosine Kinase Inhibitor
author name string	wds:Q91354180-4434DECE-6663-41CC-8B6E-D4BF50507C37 wds:Q91354180-4E877D0E-45F7-4005-B999-9AE1915100F9 wds:Q91354180-750290F8-939F-48BA-956B-87D75C071DE6 wds:Q91354180-B365A173-7968-40E3-A2C3-530CF75F0414 wds:Q91354180-C97FBFF7-9458-4165-B3FE-22586F22F1DD wds:Q91354180-EF4C11AE-F61B-484F-A9C0-1F031AA23E63
author name string	Xianbin Tian Wen Lin Handan He Tycho Heimbach Florence Hourcade-Potelleret Nicholas Horvath
rdfs:label	Physiologically Based Pharmacokinetic Modeling to Supplement Nilotinib Pharmacokinetics and Confirm Dose Selection in Pediatric Patients (en) Physiologically Based Pharmacokinetic Modeling to Supplement Nilotinib Pharmacokinetics and Confirm Dose Selection in Pediatric Patients (nl)
skos:prefLabel	Physiologically Based Pharmacokinetic Modeling to Supplement Nilotinib Pharmacokinetics and Confirm Dose Selection in Pediatric Patients (en) Physiologically Based Pharmacokinetic Modeling to Supplement Nilotinib Pharmacokinetics and Confirm Dose Selection in Pediatric Patients (nl)
name	Physiologically Based Pharmacokinetic Modeling to Supplement Nilotinib Pharmacokinetics and Confirm Dose Selection in Pediatric Patients (en) Physiologically Based Pharmacokinetic Modeling to Supplement Nilotinib Pharmacokinetics and Confirm Dose Selection in Pediatric Patients (nl)
author	wds:Q91354180-D2787ED0-C3BE-42B5-BB67-2D68CF83679C
author	François Pierre Combes
title	wds:Q91354180-CCDB8645-8684-4950-BE98-A68CD1631D98
title	Physiologically Based Pharmacokinetic Modeling to Supplement Nilotinib Pharmacokinetics and Confirm Dose Selection in Pediatric Patients (en)
page(s)	wds:Q91354180-499F3851-14E1-46B8-A693-C89A0D1A2B89
page(s)	2191-2198
instance of	wds:Q91354180-E1472BE1-2608-42DF-B719-0EA1B80788DB
instance of	scholarly article
PubMed ID	wds:Q91354180-0CC428D7-5F1F-417A-8ECA-A51733D1DF93
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30721710
PubMed ID	30721710
published in	wds:Q91354180-69CA6E51-1252-474E-9B1B-776366652110
published in	Journal of Pharmaceutical Sciences
issue	wds:Q91354180-39B3CE14-9A2B-430A-91DA-E1E3E3056AEB
volume	wds:Q91354180-D71C9D7B-C51A-48AA-A29C-7558638D27EF
issue	6
volume	108
DOI	wds:Q91354180-3B9B2727-EC4D-4256-AEC3-266235947436
DOI	http://dx.doi.org/10.1016/J.XPHS.2019.01.028
DOI	10.1016/J.XPHS.2019.01.028
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q91354180
is cites work of	Clinical data combined with modelling and simulation indicate unchanged drug-drug interaction magnitudes in the elderly A STELLA simulation model for in vitro dissolution testing of respirable size particles Phase I study of vinblastine in combination with nilotinib in children, adolescents, and young adults with refractory or recurrent low-grade glioma Physiologically Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics
is cites work of	wds:Q98284637-950CA706-6418-43FA-A727-465B0816A3DD wds:Q91768480-47B77AF6-1980-4F26-BF3F-64FF45A6A565 wds:Q97528128-85940EE8-4198-4BFF-A632-E9C4851BC350 wds:Q104058387-BD28E55B-BCF5-4EAB-BA2E-57E4F6FA340A wds:Q89819938-75D406F8-4E6B-4410-B30F-61BB1296B28E

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