About: William J. Murphy

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An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

immunologist

Attributes	Values
rdf:type	Item
field of work	wds:Q91170042-A21D1618-BD75-4824-80FE-7EAAF62285C5
field of work	immunology
description	immunologist (en) ikertzailea (eu) 연구원 (ko) 研究者 (ja)
rdfs:label	William J. Murphy (en) William J. Murphy (nl) উইলিয়াম জে মার্ফি (bn)
skos:prefLabel	William J. Murphy (en) William J. Murphy (nl) উইলিয়াম জে মার্ফি (bn)
name	William J. Murphy (en) William J. Murphy (nl) উইলিয়াম জে মার্ফি (bn)
ResearchGate contributions ID	wds:Q91170042-26f6160f-4671-b956-63b8-a169b7decb16 wds:Q91170042-471dde99-4e5c-f550-e102-e6638cf0efb4
ResearchGate contributions ID	2143689479 59066546
Scopus author ID	wds:Q91170042-DA51C8F5-D33D-40DB-97F2-C607587C856D
Scopus author ID	55757782229
given name	wds:Q91170042-DCFEA07A-935E-4CBF-B97F-A2C32134A090 wds:Q91170042-b0835b32-4af0-043d-611a-4efb75b35d23
given name	Joseph William
instance of	wds:Q91170042-3995E150-37FA-4E27-91AB-99753AED6B96
instance of	Homo sapiens
Google Knowledge Graph ID	wds:Q91170042-946049b0-4c91-1f13-4156-5561499e7666
Google Knowledge Graph ID	http://g.co/kg/g/11jg8pdf76
Google Knowledge Graph ID	/g/11jg8pdf76
Google Scholar author ID	wds:Q91170042-33ED6795-593D-4757-B078-A9F389DF1057
Google Scholar author ID	eS0orSYAAAAJ
skos:altLabel	William Murphy (en) William Murphy (nl) William J Murphy (en) William J Murphy (nl) William Joseph Murphy (en)
occupation	wds:Q91170042-35F33B94-1C92-4AC8-B826-4B8E1A321632 wds:Q91170042-D4DF7B0B-661B-4260-A32E-68D77C962BE0
employer	wds:Q91170042-937E97E2-5E58-427D-B20D-4F1DB8460744 wds:Q91170042-E7D94077-D937-4027-8E4D-48FA19DC210E wds:Q91170042-EA90D94F-279B-414C-BA18-C1D34CE6B109
different from	wds:Q91170042-a1053325-4588-9175-097d-f4ae6ded7ebf
sex or gender	wds:Q91170042-5ADF3BFF-14DD-40CA-A9FD-F894D7A78EBA
educated at	wds:Q91170042-2FA21072-4C03-4224-8E1D-A8F3E3D52F2D wds:Q91170042-5CC349E2-E6C8-4D81-8710-C2BDDD33E206
family name	wds:Q91170042-DE9448DC-2CD1-431C-B300-E8C7863EB54F
occupation	immunologist researcher
employer	University of Nevada, Reno University of California, Davis Frederick National Laboratory for Cancer Research
different from	William J Murphy
sex or gender	male
educated at	Rutgers University University of Texas Southwestern Medical Center
family name	Murphy
ORCID iD	wds:Q91170042-5FC76C22-CAE9-405F-9DFE-F8FDBBA41140
ORCID iD	https://orcid.org/0000-0002-2793-401X
ORCID iD	0000-0002-2793-401X
is owl:sameAs of	William J. Murphy
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q91170042
is author of	Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans NK inhibitory-receptor blockade for purging of leukemia: effects on hematopoietic reconstitution Engraftment and activity of anti-CD3-activated human peripheral blood lymphocytes transferred into mice with severe combined immune deficiency. Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy Immunobiology of allogeneic hematopoietic stem cell transplantation TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells. Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia. Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition Ibrutinib treatment ameliorates murine chronic graft-versus-host disease IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. Advances in graft-versus-host disease biology and therapy Advantages and clinical applications of natural killer cells in cancer immunotherapy Donor-type activated natural killer cells promote marrow engraftment and B cell development during allogeneic bone marrow transplantation Increased antitumor effects using IL-2 with anti-TGF-β reveals competition between mouse NK and CD8 T cells. Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion The neutrophil granule protein cathepsin G activates murine T lymphocytes and upregulates antigen-specific IG production in mice Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy. Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP. Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2(b) bone marrow cell allografts. An absence of T cells in murine bone marrow allografts leads to an increased susceptibility to rejection by natural killer cells and T cells

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