About: Renoprotective effects of the novel prostaglandin EP4 receptor-selective antagonist ASP7657 in 5/6 nephrectomized chronic kidney disease rats

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About: Renoprotective effects of the novel prostaglandin EP4 receptor-selective antagonist ASP7657 in 5/6 nephrectomized chronic kidney disease rats Goto Sponge NotDistinct Permalink

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scientific article published on 15 December 2018

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 2018 (uk) article scientifique publié en 2018 (fr) artículu científicu espublizáu n'avientu de 2018 (ast) scientific article published on 15 December 2018 (en) գիտական հոդված հրատարակված 2018 թվականի դեկտեմբերի 15-ին (hy)
publication date	wds:Q90563390-B94EB679-EF41-4F73-85F4-2A2724A71AD3
publication date	2018-12-15 00:00:00Z (xsd:dateTime)
cites work	wds:Q90563390-1D478285-31DF-4570-B859-BC7C0562A852 wds:Q90563390-325F10BC-D518-4A19-8DC1-ABC2B81BA17C wds:Q90563390-3A57CA47-53BA-4A18-90BD-2A23CA8B877F wds:Q90563390-50B8A535-940C-44EA-BA16-316014F65360 wds:Q90563390-51048DD5-59BB-4BD8-86A1-42B60E0B5628 wds:Q90563390-5B4DEC02-887E-4778-8A2C-972E82588D5C wds:Q90563390-5E1295D3-38C2-46EA-BCF3-3D9D0F4D9711 wds:Q90563390-75F6D75C-396F-4FC4-9D3A-A1412814B557 wds:Q90563390-7607BE7A-2F00-4852-BC84-CA1119C66D55 wds:Q90563390-795798C3-92F7-42FD-B9B4-10E27C96CC18 wds:Q90563390-7BB34371-F8A2-46BB-9672-7DCE596C69E2 wds:Q90563390-86D4AD47-D900-4555-8643-2777F45BAD26 wds:Q90563390-8D5A0089-12DF-4D4D-A083-E168FBA3D5A9 wds:Q90563390-8E952D66-F13B-44E8-88E8-29909AF1BE45 wds:Q90563390-9187F456-B3F0-49CF-90CC-07A0F9FDC27D wds:Q90563390-95534A77-0A4B-4F13-ACCE-12064CD917B7 wds:Q90563390-9EE24765-EE74-4C24-821B-042B396F046B wds:Q90563390-A78BC277-7C0D-406B-A10D-EA390632799E wds:Q90563390-A909E4BA-3319-42A6-B533-B4E20F129894 wds:Q90563390-AB81E737-4F11-4D83-800B-D966FB334E03 wds:Q90563390-BD08A639-FF71-4ADB-97D9-AECB48F089E3 wds:Q90563390-C5F6EC3D-18C8-47F3-839A-13C77EC64FF8 wds:Q90563390-CB3F98A8-2C3C-4737-BC39-037BAC7AAD6B wds:Q90563390-D7336320-0422-4ECD-A8D5-D5C559E36157 wds:Q90563390-DA01855C-FBCD-43DE-9EEE-076D2C9A3B38 wds:Q90563390-DD5B5BB0-7E64-48B8-8DEF-A677AB97BCED wds:Q90563390-E03BA9C3-530B-4B84-8B67-3F3B0B2867BA wds:Q90563390-EA66E5BB-E197-47FC-A47F-A826FF54A26F wds:Q90563390-EB318CF7-CA50-447B-8189-B0FE4FACFF51
cites work	Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats Stimulation of renin release by prostaglandin E2 is mediated by EP2 and EP4 receptors in mouse kidneys EP4 inhibition attenuates the development of diabetic and non-diabetic experimental kidney disease The prostanoid EP4 receptor and its signaling pathway. Chronic administration of EP4-selective agonist exacerbates albuminuria and fibrosis of the kidney in streptozotocin-induced diabetic mice through IL-6. EP(1) and EP(4) receptors mediate prostaglandin E(2) actions in the microcirculation of rat kidney. Increased expression of endothelial cell nitric oxide synthase (ecNOS) in afferent and glomerular endothelial cells is involved in glomerular hyperfiltration of diabetic nephropathy Prostanoid receptors: structures, properties, and functions Activation of the renin-angiotensin system and chronic hypoxia of the kidney A maladaptive role for EP4 receptors in podocytes Mechanisms of progression of chronic kidney disease Tubulointerstitial injury and the progression of chronic kidney disease Glomerular hyperfiltration: definitions, mechanisms and clinical implications. The PGE(2)-EP4 receptor is necessary for stimulation of the renin-angiotensin-aldosterone system in response to low dietary salt intake in vivo Review: renal protection by inhibition of the renin-angiotensin-aldosterone system Common pathophysiological mechanisms of chronic kidney disease: therapeutic perspectives. Targeting the renin angiotensin system for remission/regression of chronic kidney disease Importance of blood pressure control in chronic kidney disease. Effects of sodium-glucose cotransporter 2 selective inhibitor ipragliflozin on hyperglycaemia, oxidative stress, inflammation and liver injury in streptozotocin-induced type 1 diabetic rats Biphasic actions of prostaglandin E(2) on the renal afferent arteriole : role of EP(3) and EP(4) receptors Regulation of renin secretion by renal juxtaglomerular cells. A novel prostaglandin E receptor subtype agonist, 0N0-4819, attenuates acute experimental liver injury in rats Antagonist for atrial natriuretic peptide receptors ameliorates glomerular hyperfiltration in diabetic rats PGE2, Kidney Disease, and Cardiovascular Risk: Beyond Hypertension and Diabetes Renoprotective effects of novel interleukin-1 receptor-associated kinase 4 inhibitor AS2444697 through anti-inflammatory action in 5/6 nephrectomized rats. Pharmacological properties of ASP7657, a novel, potent, and selective prostaglandin EP4 receptor antagonist Novel drugs and intervention strategies for the treatment of chronic kidney disease Losartan ameliorates renal injury, hypertension, and adipocytokine imbalance in 5/6 nephrectomized rats
author name string	wds:Q90563390-1516BEC1-D748-4BA7-88A9-331180D2EBBA wds:Q90563390-6F968A98-BE85-4B82-B57B-08631A4577B7 wds:Q90563390-788AFAAD-2FB6-412E-AB24-353D2AF2A252 wds:Q90563390-8F3108AB-7EE5-4023-AE49-751644A6753E
author name string	Hiroyuki Yoshida Koichi Wada Tohru Ugawa Eisuke Nozawa
rdfs:label	Renoprotective effects of the novel prostaglandin EP4 receptor-selective antagonist ASP7657 in 5/6 nephrectomized chronic kidney disease rats (en) Renoprotective effects of the novel prostaglandin EP4 receptor-selective antagonist ASP7657 in 5/6 nephrectomized chronic kidney disease rats (nl)
skos:prefLabel	Renoprotective effects of the novel prostaglandin EP4 receptor-selective antagonist ASP7657 in 5/6 nephrectomized chronic kidney disease rats (en) Renoprotective effects of the novel prostaglandin EP4 receptor-selective antagonist ASP7657 in 5/6 nephrectomized chronic kidney disease rats (nl)
name	Renoprotective effects of the novel prostaglandin EP4 receptor-selective antagonist ASP7657 in 5/6 nephrectomized chronic kidney disease rats (en) Renoprotective effects of the novel prostaglandin EP4 receptor-selective antagonist ASP7657 in 5/6 nephrectomized chronic kidney disease rats (nl)
author	wds:Q90563390-29635354-F9B1-48B1-9473-55097469958F
author	Kazuhiko Mizukami
title	wds:Q90563390-F2C6F9E0-38A6-4859-8AC2-81D82B23F7E5
title	Renoprotective effects of the novel prostaglandin EP4 receptor-selective antagonist ASP7657 in 5/6 nephrectomized chronic kidney disease rats (en)
page(s)	wds:Q90563390-F0E938EB-6BCC-4C20-9B1F-7C19F7F2F5D5
page(s)	451-459
instance of	wds:Q90563390-A7F042B8-C6AE-4950-839B-E9D12F3CB2DC
instance of	scholarly article
main subject	wds:Q90563390-8D08D644-12D2-4468-A000-03B8CBFEC86A
main subject	chronic renal insufficiency
PubMed ID	wds:Q90563390-2045E401-557C-4DB7-9C65-5269905E9A70
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30554341
PubMed ID	30554341
published in	wds:Q90563390-1B958C87-94D9-48CC-B89A-F194FA3BC789
published in	Naunyn-Schmiedeberg's Archives of Pharmacology
issue	wds:Q90563390-81A7A96D-F64C-4C25-BF5F-F60E80F9BE7A
volume	wds:Q90563390-FAF1F2E8-6335-4D8E-B16E-24F0E9749F75
issue	4
volume	392

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