About: Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in Trypanosoma brucei: Intracellular Localization and Properties of the Enzyme.

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About: Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in Trypanosoma brucei: Intracellular Localization and Properties of the Enzyme. Goto Sponge NotDistinct Permalink

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scientific article published on 07 August 2019

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rdf:type	Item
description	wetenschappelijk artikel (nl) artículu científicu espublizáu n'agostu de 2019 (ast) im August 2019 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована 7 серпня 2019 (uk) scientific article published on 07 August 2019 (en)
publication date	wds:Q88143603-A541BB13-DC4E-4B82-A794-8B9556E2D552
publication date	2019-08-07 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q88143603-B7F992AD-E892-42C6-98C3-356745BBFEC4
language of work or name	English
cites work	wds:Q88143603-02DC5DAE-B2D3-496B-9817-9884F3ADA65C wds:Q88143603-045E02F4-F4B1-4439-9359-9EB9089B8167 wds:Q88143603-097211C2-2237-4313-B89A-E61BC555D471 wds:Q88143603-0DA3B44F-8D82-4936-ACE9-562CBB0253E7 wds:Q88143603-15ED9898-B3C5-4284-AE6A-39864DEB5F51 wds:Q88143603-19092F62-B830-4E32-8AD8-52209EC45743 wds:Q88143603-1F27BFEE-6AAF-4DCD-A756-AF7B95EDFA39 wds:Q88143603-3A9746CB-0951-45EF-9F3E-6383195563B9 wds:Q88143603-3FCFD8D6-C092-4603-B4FE-D02DD24778B8 wds:Q88143603-49AD3338-617B-46DF-AA28-5FC578807992 wds:Q88143603-5125C5A1-77B6-4FAB-B111-5C8352CEFCB3 wds:Q88143603-59C7DE12-7A0F-4952-A346-9225514E1A27 wds:Q88143603-5B0005A2-8BA1-4DB6-B3C5-AF26DA31D71E wds:Q88143603-652B60FC-FFF1-4E73-88D9-8E67AE6FAC42 wds:Q88143603-680C0910-FB25-4337-88AE-B31137658160 wds:Q88143603-694E1F30-323C-4C5F-9F45-4B8F7139D92A wds:Q88143603-6C9E748C-6FCF-486C-8B03-D3EF615DF9E5 wds:Q88143603-7225BBDF-5AC9-4623-AE0F-1C8DA5CB6C32 wds:Q88143603-72FEFD6D-C464-47A4-8F4A-F51BFB72C767 wds:Q88143603-8697A38C-C59F-4039-84F0-B626DE8F395E wds:Q88143603-8907F6D2-676B-4899-AA1A-D10E034852F3 wds:Q88143603-8D46A415-37F8-41BC-8773-F78D9793307B wds:Q88143603-96E09A6B-A8A0-4B47-B1AE-8D1D5AE15E01 wds:Q88143603-9BD18C90-8A64-4A9F-B215-CE68365CB861 wds:Q88143603-9E17D321-8EA9-46C5-9D7B-1A74009D9CD6 wds:Q88143603-9FB6CE1C-2A23-47A2-95C8-F46251F99FE2 wds:Q88143603-AC2CC15A-8C62-48A4-A3EE-64E106E6F939 wds:Q88143603-BCA9937C-DE26-4681-BF61-B89219CDCA77 wds:Q88143603-DB1FA8C7-71F3-454E-A339-3C0656030864 wds:Q88143603-E7F98B6E-339B-4D16-9F27-507D0690ADE6 wds:Q88143603-F1636326-C069-4664-A6A7-63D69A4A6016 wds:Q88143603-F300E737-2035-4B5B-B9EE-FB247E038E10 wds:Q88143603-FB352F2C-E028-4AAB-B4CA-CD285F208BB5 wds:Q88143603-FDFE1E8B-8ED3-4934-A547-27414619FC2D wds:Q88143603-FEBA4080-61E0-46F2-8A2B-144BDC9930AB wds:Q88143603-FED653C3-FFE7-4683-BE75-6352CFC01FC2
cites work	Structure of human cytidine deaminase bound to a potent inhibitor Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria Crystal structure of the tetrameric cytidine deaminase from Bacillus subtilis at 2.0 A resolution Bifunctional thymidylate synthase-dihydrofolate reductase in protozoa The AID/APOBEC family of nucleic acid mutators. A guided tour into subcellular colocalization analysis in light microscopy A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Fiji: an open-source platform for biological-image analysis A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions Mitochondria are a major site for folate and thymidylate synthesis in plants. Regulated processive transcription of chromatin by T7 RNA polymerase in Trypanosoma brucei. Role of tyrosine 33 residue for the stabilization of the tetrameric structure of human cytidine deaminase Recombinant human cytidine deaminase: expression, purification, and characterization The exosome of Trypanosoma brucei Cytidine deaminase genetic variants influence RNA expression and cytarabine cytotoxicity in acute myeloid leukemia Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei Pyrimidine Salvage Enzymes Are Essential for De Novo Biosynthesis of Deoxypyrimidine Nucleotides in Trypanosoma brucei Pyrimidine requirements in deoxyuridine triphosphate nucleotidohydrolase deficient Trypanosoma brucei mutants. Down-Regulating Gene Expression by RNA Interference in Trypanosoma brucei Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase Nucleoside diphosphate kinase of Trypanosoma brucei. Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer Depletion of dimeric all-alpha dUTPase induces DNA strand breaks and impairs cell cycle progression in Trypanosoma brucei. Flagellar pocket restructuring through the Leishmania life cycle involves a discrete flagellum attachment zone. Cellular landmarks of Trypanosoma brucei and Leishmania mexicana. Human African trypanosomiasis High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects. Trypanosomes lacking uracil-DNA glycosylase are hypersensitive to antifolates and present a mutator phenotype. The Long Wait for a New Drug for Human African Trypanosomiasis Cloning, expression, and purification of cytidine deaminase from Arabidopsis thaliana Structural, kinetic, and mutational studies of the zinc ion environment in tetrameric cytidine deaminase. Inactivation of the cytosolic and mitochondrial serine hydroxymethyl transferase genes in Leishmania major. Targeting Kinetoplastid and Apicomplexan Thymidylate Biosynthesis as an Antiprotozoal Strategy
author name string	wds:Q88143603-38EB46DB-1483-430D-9791-5E666E07CC1C wds:Q88143603-3CB5AAD4-733A-4CF4-B1C4-1A9A8BE2F829 wds:Q88143603-7DDF82BB-22E9-47C8-8032-C18815635FB8 wds:Q88143603-A91B19BB-0682-493D-AFD9-7F1437493E97 wds:Q88143603-B69AA37A-FCE3-4DB4-9A05-6E7C8A37101D wds:Q88143603-E31FA373-4FF5-4841-AE08-043EADF90A9B wds:Q88143603-EB89925B-C90C-4BF3-9F3B-434D101FE530
author name string	Juana Carrero-Lérida Dolores González-Pacanowska Guiomar Pérez-Moreno Víctor M Castillo-Acosta Maria Valente Luis Miguel Ruiz-Pérez Ana Moro-Bulnes
rdfs:label	Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in Trypanosoma brucei: Intracellular Localization and Properties of the Enzyme. (en) Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in Trypanosoma brucei: Intracellular Localization and Properties of the Enzyme. (nl)
skos:prefLabel	Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in Trypanosoma brucei: Intracellular Localization and Properties of the Enzyme. (en) Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in Trypanosoma brucei: Intracellular Localization and Properties of the Enzyme. (nl)

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