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description
| - wetenschappelijk artikel (nl)
- наукова стаття, опублікована в березні 2011 (uk)
- im März 2011 veröffentlichter wissenschaftlicher Artikel (de)
- scientific article published on 10 March 2011 (en)
- artículu científicu espublizáu en marzu de 2011 (ast)
- 2011 թվականի մարտի 10-ին հրատարակված գիտական հոդված (hy)
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| - Shun Ishibashi
- Satoshi Omura
- Chiara Degirolamo
- Daisuke Matsuda
- Lawrence L Rudel
- Hiroshi Tomoda
- Kent Sakai
- Hiroaki Yagyu
- Taichi Ohshiro
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rdfs:label
| - Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia (en)
- Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia (nl)
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skos:prefLabel
| - Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia (en)
- Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia (nl)
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name
| - Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia (en)
- Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia (nl)
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title
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title
| - Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia (en)
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DOI
| - 10.1161/ATVBAHA.111.223552
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is cites work
of | - Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice
- Acute sterol o-acyltransferase 2 (SOAT2) knockdown rapidly mobilizes hepatic cholesterol for fecal excretion
- Characterization of two acetyltransferase genes in the pyripyropene biosynthetic gene cluster from Penicillium coprobium
- Estrogen signalling and the metabolic syndrome: targeting the hepatic estrogen receptor alpha action
- Antifungal activity of extracts from Atacama Desert fungi against Paracoccidioides brasiliensis and identification of Aspergillus felis as a promising source of natural bioactive compounds
- Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophages
- A specific cholesterol metabolic pathway is established in a subset of HCCs for tumor growth.
- Selective inhibition of sterolO-acyltransferase 1 isozyme by beauveriolide III in intact cells
- New verticilides, inhibitors of acyl-CoA:cholesterol acyltransferase, produced by Verticillium sp. FKI-2679.
- Using self-organizing map (SOM) and support vector machine (SVM) for classification of selectivity of ACAT inhibitors
- Deletion of sterol O-acyltransferase 2 (SOAT2) function in mice deficient in lysosomal acid lipase (LAL) dramatically reduces esterified cholesterol sequestration in the small intestine and liver
- New pyripyropene A derivatives, highly SOAT2-selective inhibitors, improve hypercholesterolemia and atherosclerosis in atherogenic mouse models
- PRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient mice
- ACAT inhibition reduces the progression of preexisting, advanced atherosclerotic mouse lesions without plaque or systemic toxicity
- Involvement of toll-like receptor 2 and 4 in association between dyslipidemia and osteoclast differentiation in apolipoprotein E deficient rat periodontium
- Sterol O-Acyltransferase 2 Contributes to the Yolk Cholesterol Trafficking during Zebrafish Embryogenesis
- Clonoamide, a new inhibitor of sterol O-acyltransferase, produced by Clonostachys sp. BF-0131.
- Mechanisms and regulation of cholesterol homeostasis
- Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2.
- Sterol O-Acyltransferase 2-Driven Cholesterol Esterification Opposes Liver X Receptor-Stimulated Fecal Neutral Sterol Loss
- Celludinones, new inhibitors of sterol O-acyltransferase, produced by Talaromyces cellulolyticus BF-0307
- Voluhemins, new inhibitors of sterol O-acyltransferase, produced by Volutella citrinella BF-0440
- TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2.
- The ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters
- In vitro metabolism of pyripyropene A and ACAT inhibitory activity of its metabolites.
- Structural basis for catalysis and substrate specificity of human ACAT1
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