About: Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment

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scientific article published on 18 February 2010

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в лютому 2010 (uk) im Februar 2010 veröffentlichter wissenschaftlicher Artikel (de) scientific article published on 18 February 2010 (en) գիտական հոդված հրատարակված 2010 թվականի փետրվարի 18-ին (hy) artículu científicu espublizáu en febreru de 2010 (ast)
publication date	wds:Q82942870-9D0D1799-5C6B-4BA5-8F14-FFE0AAB8088E
publication date	2010-02-18 00:00:00Z (xsd:dateTime)
exact match	wds:Q82942870-8C0BDE24-5481-4D88-9DF5-BAC4C601860E
exact match	https://scigraph.springernature.com/pub.10.1038/leu.2010.14
cites work	wds:Q82942870-067A2B96-24C8-4453-A0F1-E2E54854FA7A wds:Q82942870-1902AAA9-CA49-4E9D-9D2F-FD4956BD9A89 wds:Q82942870-23F9A8DA-7E3D-4E2E-9125-616AC7E795F0 wds:Q82942870-3DAFA6EA-12F8-43CF-B0A9-43E73517F932 wds:Q82942870-4B3224AD-DBDB-4289-9A32-A7B7F2A949A2 wds:Q82942870-5466D373-CCF9-4D3B-A3C6-2B66942BF2BF wds:Q82942870-5E0BBA37-187E-4E38-941C-B6A72A19CDBD wds:Q82942870-9F23EEEC-EFFD-4AD7-851C-C8ECDD3044E4 wds:Q82942870-ACEAE0EB-E569-4211-955C-948FA473ABB1 wds:Q82942870-AF415880-8EE4-40C7-9B34-7CDF03984619 wds:Q82942870-EAB7FA9A-15DD-4C63-82BC-8FD082B06C9A wds:Q82942870-FB173DE1-49D6-4DB8-A2EC-8DF928A44839
cites work	New insights to the MLL recombinome of acute leukemias Origins of chromosome translocations in childhood leukaemia A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial. Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement. DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis Infant leukemia, topoisomerase II inhibitors, and the MLL gene Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL. Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia. Monitoring minimal residual disease by quantification of genomic chromosomal breakpoint sequences in acute leukemias with MLL aberrations. Diagnostic tool for the identification of MLL rearrangements including unknown partner genes Acute lymphoblastic leukemia with t(4;11) in children 1 year and older: The 'big sister' of the infant disease? Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further process
author name string	wds:Q82942870-070175BB-8B36-4AD4-8E05-467EB025E169 wds:Q82942870-110B0DD3-77CA-4DAA-90DE-36E0E5947289 wds:Q82942870-16F8BBB8-450B-4290-AF81-B15603A6F636 wds:Q82942870-3BD2F426-700C-4D6A-95E6-1D16668071EC wds:Q82942870-4144AD5C-737F-4BD5-91C4-2368510A8FE7 wds:Q82942870-51D47743-0D03-443C-9BD6-1936AD667B83 wds:Q82942870-79CE15E5-19BC-4DD6-8100-3D10A9328B43 wds:Q82942870-7BA08255-B33E-4735-AF93-54981C13AF3E wds:Q82942870-88061B78-E20C-4398-B21A-E645E5F24116 wds:Q82942870-89307084-2099-42B7-A7A4-A77DA8525672 wds:Q82942870-8BCAF488-0B61-4C25-B0C9-A19A701BC794 wds:Q82942870-9F31D8FC-39E9-4D19-9E7C-7D18A8F7A30F wds:Q82942870-B12765D2-939C-4CF8-8516-1A05A5D7F338 wds:Q82942870-BDF7FEFF-4E29-4167-948E-D69089EB06F5 wds:Q82942870-C54FC7E2-F79F-4353-987A-E71759BEC06F wds:Q82942870-DDDFE704-8FD3-441C-8982-38389B3D795B
author name string	R Jung T Langer V H J van der Velden W Rascher M G Valsecchi M Schrappe M Stanulla R Pieters M Metzler A Teigler-Schlegel M L den Boer U Jacobs P De Lorenzo M Krumbholz E R Panzer-Gruemayer A Moericke
rdfs:label	Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment (en) Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment (nl)
skos:prefLabel	Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment (en) Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment (nl)
name	Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment (en) Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment (nl)
author	wds:Q82942870-569EA850-92A7-4985-A0B7-CB7BAFC99CD0 wds:Q82942870-74254B0A-4425-48F2-9DA1-3EB3DA9F897F
author	Jacques Van Dongen Thomas Keller
title	wds:Q82942870-7B4BE13C-1857-4CFA-ABA3-6B196889B8EC
title	Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment (en)
page(s)	wds:Q82942870-F33FE661-1510-4EB6-A67F-744821B232ED
page(s)	903-907
instance of	wds:Q82942870-84F8AD7F-ACC9-4FAA-8D06-2623C0BEA27D
instance of	scholarly article
main subject	wds:Q82942870-EAE79549-BCEB-462A-B100-6D9EF9979130
main subject	lymphoblastic leukemia
PubMed ID	wds:Q82942870-383EA53E-5405-4E68-AAC2-9E67DBF6B78C
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20164851
PubMed ID	20164851
published in	wds:Q82942870-06C09BBD-0331-4AAE-A20B-9CAE251881C4
published in	Leukemia
issue	wds:Q82942870-0216D3BC-1D96-4C98-81DE-729B0FA9F02D
volume	wds:Q82942870-B522E52F-0560-4244-B1A3-AB838494AB6D
issue	4
volume	24
DOI	wds:Q82942870-B198567A-846E-4721-BA19-9A28121F1DED
DOI	http://dx.doi.org/10.1038/LEU.2010.14
DOI	10.1038/LEU.2010.14
Dimensions Publication ID	wds:Q82942870-057D6978-C911-4B7D-B882-5F5E0FE2ECAC
Dimensions Publication ID	1038098675
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q82942870

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