About: Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors

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About: Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors Goto Sponge NotDistinct Permalink

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scientific article published on 16 December 2010

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2010 (fr) наукова стаття, опублікована в грудні 2010 (uk) scientific article published on 16 December 2010 (en) artículu científicu espublizáu n'avientu de 2010 (ast)
publication date	wds:Q82906878-40D9345C-6F66-4F3D-B11B-7E851ACE4D7D
publication date	2010-12-16 00:00:00Z (xsd:dateTime)
exact match	wds:Q82906878-F371819A-8B45-40A7-AAC6-8D223C26E81A
exact match	https://scigraph.springernature.com/pub.10.1007/s00280-010-1544-1
author name string	wds:Q82906878-18D5517E-5B48-4561-AD4F-7762046CFADC wds:Q82906878-21EAEF22-62B1-486B-951A-8F12E1D0C62B wds:Q82906878-26B77A5A-4EA0-472C-9B99-F4383C2B7592 wds:Q82906878-399A996D-B862-4B08-8182-99E5C059066C wds:Q82906878-39AFDF81-9ACE-4E80-910F-ED777B8ADBEE wds:Q82906878-4449175E-3AC3-4D2B-A6E5-574CCD085F09 wds:Q82906878-46E9D959-F2A6-49CF-9CBB-3BDDC2812D71 wds:Q82906878-4D6AFA6B-B20A-4F0C-9441-6FBBDAE6C093 wds:Q82906878-6941463A-D4EC-4521-A5C2-A07CDEC0E5D3 wds:Q82906878-76FA364B-F279-4E59-B2FF-BDC641209A3D wds:Q82906878-9EEC3C1B-7E39-4B82-A5FA-C5437BC94738 wds:Q82906878-ADE42519-48B5-461D-B84A-63890B1C6B4A wds:Q82906878-ED8B4A40-B564-450B-9B70-816B0C98363D
author name string	T Sasaki T Kawaguchi T Doi H Murakami N Yamamoto T Yoshino A Ohtsu N Fuse N Boku Y Onozawa C-P Hsu G Friberg K S Gorski
rdfs:label	Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors (en) Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors (nl)
skos:prefLabel	Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors (en) Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors (nl)
name	Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors (en) Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors (nl)
title	wds:Q82906878-D1CFE134-44CD-43CF-9998-39203720F9CD
title	Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors (en)
page(s)	wds:Q82906878-91E7A628-3D80-4EF7-9454-7AC9B2705DB2
page(s)	733-741
instance of	wds:Q82906878-5893D327-B5B9-408A-B3F2-3BB7F916539A
instance of	scholarly article
main subject	wds:Q82906878-9E714B5A-ED67-42F7-ADE3-A8FB330DFFAD
main subject	apoptotic process
PubMed ID	wds:Q82906878-D311FE1A-9F79-49EE-8829-70F600213E82
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21161528
PubMed ID	21161528
published in	wds:Q82906878-E777AA08-8495-4E25-9439-6F408272EFA0
published in	Cancer Chemotherapy and Pharmacology
issue	wds:Q82906878-29C37C2B-BCD1-4491-A186-5BCB4C44E0ED
volume	wds:Q82906878-F804467D-56E7-4F6A-8257-CB35D73788FC
issue	3
volume	68
DOI	wds:Q82906878-11447775-6AE3-4D23-A7FA-9190CCB5094C
DOI	http://dx.doi.org/10.1007/S00280-010-1544-1
DOI	10.1007/S00280-010-1544-1
Dimensions Publication ID	wds:Q82906878-CEFFD1AD-242A-45E2-9235-3B5DDA88709C
Dimensions Publication ID	1037992075
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q82906878
is cites work of	Trial Watch: Tumor-targeting monoclonal antibodies in cancer therapy Getting TRAIL back on track for cancer therapy Death receptors as targets in cancer Advances in targeting cell surface signalling molecules for immune modulation Anticancer activity of the type I insulin-like growth factor receptor antagonist, ganitumab, in combination with the death receptor 5 agonist, conatumumab Trial Watch: Monoclonal antibodies in cancer therapy A New Player in the Development of TRAIL Based Therapies for Hepatocarcinoma Treatment: ATM Kinase Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapy Phase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening TRAIL receptor agonist conatumumab with modified FOLFOX6 plus bevacizumab for first-line treatment of metastatic colorectal cancer: A randomized phase 1b/2 trial Targeted therapies in non-small cell lung carcinoma: what have we achieved so far? Pentamerisation of a scFv directed against TRAIL receptor 2 increases its antitumour efficacy Death Receptors: New Opportunities in Cancer Therapy. Journey of TRAIL from Bench to Bedside and its Potential Role in Immuno-Oncology. Molecular targeted approaches for treatment of pancreatic cancer. Variants of Osteoprotegerin Lacking TRAIL Binding for Therapeutic Bone Remodeling in Osteolytic Malignancies. Therapeutic applications of TRAIL receptor agonists in cancer and beyond SAHA-induced TRAIL-sensitisation of Multiple Myeloma cells is enhanced in 3D cell culture. Developing TRAIL/TRAIL death receptor-based cancer therapies. Activating Death Receptor DR5 as a Therapeutic Strategy for Rhabdomyosarcoma Novel Apoptosis-Inducing Agents for the Treatment of Cancer, a New Arsenal in the Toolbox
is cites work of	wds:Q35050195-5247BFE8-202E-47B0-97F8-DA73CF10F338 wds:Q47108799-A2206C9D-3927-45B3-B110-C08F9273E22D wds:Q33739941-92B850D0-8428-4303-81B5-DD5CEDE3364E wds:Q42623198-F4E0042F-BBBF-4D95-AAD4-99371AF374FD wds:Q36973787-25AFE51A-DE96-410C-99A0-67334C58329A wds:Q36038408-3E884C06-BD73-42D4-B60A-6643A4BCDBFC wds:Q37114025-806548D4-B3D6-4ECD-943D-6235401735F3 wds:Q39169340-B74B68FD-66CE-4C68-B838-1E7871BF1B8B wds:Q35038107-85E7A1B1-1144-4EFD-BEA2-9A108E505968 wds:Q35611366-806CB9F5-5DDE-446A-8BBE-A0E9DE7411F1 wds:Q38103591-61390ACF-9AC1-4DCE-ABAB-DD087FF66FF1 wds:Q27027460-96A90C2E-11E5-4CF7-888C-30F7B661E688 wds:Q36174910-3C242EEC-20C7-44AB-95CE-7A2222FEDC53

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