About: Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage

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About: Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage Goto Sponge NotDistinct Permalink

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scientific article published on 01 December 2004

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 2004 (uk) im Dezember 2004 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 2004 (ast) scientific article published on 01 December 2004 (en)
publication date	wds:Q81057971-ED1C21C1-8108-432F-BC11-10A0399A82DF
publication date	2004-12-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q81057971-07F1B9E5-4C89-4476-922E-324AAC64145E wds:Q81057971-11EB4D4C-E86F-4651-8079-4498B61E5EE9 wds:Q81057971-300136FF-D31A-4C9D-9112-16B5B55E41DF wds:Q81057971-6E9350EF-10E1-4B01-B082-60F649092AC4 wds:Q81057971-BE9BC82E-FD11-4C05-91F0-70012D3CB5C2 wds:Q81057971-C2C7AE32-466A-441A-912A-58E25F92BF0F
author name string	Rocky S Tuan Paul A Manner Xibin Wang Alan Horner Lillian Shum Glen H Nuckolls
rdfs:label	Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage (en) Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage (nl)
skos:prefLabel	Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage (en) Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage (nl)
name	Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage (en) Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage (nl)
title	wds:Q81057971-38D2DC16-EA75-4DEA-ABBA-9C082F727180
title	Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage (en)
page(s)	wds:Q81057971-2B89F787-E380-4A0F-AD06-7D439A71E394
page(s)	963-973
instance of	wds:Q81057971-9BF741A4-F719-4167-8C97-AD01B740811D
instance of	scholarly article
main subject	wds:Q81057971-E6988191-75B1-4DB9-AB1A-9F1E5BF4FDB4
main subject	osteoarthritis
PubMed ID	wds:Q81057971-10C0B6F6-08BE-41BC-9AC1-7A4EFCEBF4DD
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15564063
PubMed ID	15564063
published in	wds:Q81057971-E0D6A408-32A9-4A4A-B3E9-D9027AA022AF
published in	Osteoarthritis and Cartilage
issue	wds:Q81057971-3DB1E93B-2A31-4EA6-BBE9-D8B5C98464F4
volume	wds:Q81057971-466D4CD5-30D3-48AB-A60E-06D534176392
issue	12
volume	12
DOI	wds:Q81057971-675A800A-C3DD-4CB7-9579-7BD3B01FDB1B
DOI	http://dx.doi.org/10.1016/J.JOCA.2004.08.008
DOI	10.1016/J.JOCA.2004.08.008
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q81057971
is cites work of	Pomegranate extract inhibits the interleukin-1β-induced activation of MKK-3, p38α-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes. Cartilage homeostasis in health and rheumatic diseases Proteases involved in cartilage matrix degradation in osteoarthritis. Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture Stimulation of chondrocyte hypertrophy by chemokine stromal cell-derived factor 1 in the chondro-osseous junction during endochondral bone formation A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis. Transient down-regulation of cbfa1/Runx2 by RNA interference in murine C3H10T1/2 mesenchymal stromal cells delays in vitro and in vivo osteogenesis, but does not overtly affect chondrogenesis. Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis Indian hedgehog in synovial fluid is a novel marker for early cartilage lesions in human knee joint Expression profiling and functional implications of a set of zinc finger proteins, ZNF423, ZNF470, ZNF521, and ZNF780B, in primary osteoarthritic articular chondrocytes. Matrix Metalloproteinase-13 as a Target for Suppressing Corneal Ulceration Caused by Pseudomonas aeruginosa Infection Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis Reduced expression of Sfrp1 during chondrogenesis and in articular chondrocytes correlates with osteoarthritis in STR/ort mice. Inhibition of β-catenin signaling in chondrocytes induces delayed fracture healing in mice. Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes Basic fibroblast growth factor inhibits the anabolic activity of insulin-like growth factor 1 and osteogenic protein 1 in adult human articular chondrocytes Species-specific biological effects of FGF-2 in articular cartilage: implication for distinct roles within the FGF receptor family IL-1beta regulates FHL2 and other cytoskeleton-related genes in human chondrocytes Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145) Matrix metalloproteinases as therapeutic targets for idiopathic pulmonary fibrosis Role of Chondrocytes in Cartilage Formation, Progression of Osteoarthritis and Cartilage Regeneration Dysregulation of chondrogenesis in human cleidocranial dysplasia Mesenchyme-specific knockout of ESET histone methyltransferase causes ectopic hypertrophy and terminal differentiation of articular chondrocytes Fibroblast growth factor control of cartilage homeostasis Mitogen-activated protein kinases as therapeutic targets in osteoarthritis Chondrogenic differentiation potential of osteoarthritic chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation Cartilage cell clusters. Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice Characterization of the human ADAMTS-5 (aggrecanase-2) gene promoter Regulation of NFATc2 gene expression by the transcription factor Runx2 Cell-nanofiber-based cartilage tissue engineering using improved cell seeding, growth factor, and bioreactor technologies Mold-shaped, nanofiber scaffold-based cartilage engineering using human mesenchymal stem cells and bioreactor MicroRNA-9 regulates survival of chondroblasts and cartilage integrity by targeting protogenin Dual function of β-catenin in articular cartilage growth and degeneration at different stages of postnatal cartilage development Mechanical compression of articular cartilage induces chondrocyte proliferation and inhibits proteoglycan synthesis by activation of the ERK pathway: implications for tissue engineering and regenerative medicine Genome-wide DNA methylation study of hip and knee cartilage reveals embryonic organ and skeletal system morphogenesis as major pathways involved in osteoarthritis Mechanism of glycosaminoglycan-mediated bone and joint disease: implications for the mucopolysaccharidoses and other connective tissue diseases Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes. Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes Inhibition of histone deacetylases antagonized FGF2 and IL-1beta effects on MMP expression in human articular chondrocytes Correlation of the osteoarthritis susceptibility variants that map to chromosome 20q13 with an expression quantitative trait locus operating on NCOA3 and with functional variation at the polymorphism rs116855380. Combination of MEK-ERK inhibitor and hyaluronic acid has a synergistic effect on anti-hypertrophic and pro-chondrogenic activities in osteoarthritis treatment. Coptisine Prevented IL-β-Induced Expression of Inflammatory Mediators in Chondrocytes Coculture-driven mesenchymal stem cell-differentiated articular chondrocyte-like cells support neocartilage development IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation. Hyaluronan suppresses mechanical stress-induced expression of catabolic enzymes by human chondrocytes via inhibition of IL-1β production and subsequent NF-κB activation. Alterations in the Secretome of Clinically Relevant Preparations of Adipose-Derived Mesenchymal Stem Cells Cocultured with Hyaluronan The role of pyrophosphate/phosphate homeostasis in terminal differentiation and apoptosis of growth plate chondrocytes Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined with Sox9 via rAAV gene transfer Interleukin-1β induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes.

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