About: Ras-driven transformation of human nestin-positive pancreatic epithelial cells

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About: Ras-driven transformation of human nestin-positive pancreatic epithelial cells Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 2008

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rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique (publié 2008) (fr) наукова стаття, опублікована в січні 2008 (uk) im Jahr 2008 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 2008 (ast) artikull shkencor i botuar më 01 janar 2008 (sq) scientific article published on 01 January 2008 (en)
publication date	wds:Q80976294-64B489FE-A538-4E8B-9520-1D36DF4391D1
publication date	2008-01-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q80976294-040162A9-7B26-4D2A-986E-D2AE80737348 wds:Q80976294-0541035A-308C-430F-8DBB-CEE6C3B26AB1 wds:Q80976294-08E1D018-7134-4DD5-9A8D-0C04B6BC4952 wds:Q80976294-093E0FA0-B0E7-4262-BE4D-DA7B6F44F3A8 wds:Q80976294-15AB5863-3F5C-4CA9-AB4D-FAF2B9206D61 wds:Q80976294-1826539D-9D7A-4D49-A985-57B69B7AFC2B wds:Q80976294-1AE989C0-B9FB-4755-AA7F-B6AB1A82AEC7 wds:Q80976294-2312EC37-E14A-4261-B549-C4D61BD25EFD wds:Q80976294-370EB848-A07D-408B-8E80-C6C745E95677 wds:Q80976294-3B2A133C-261E-4079-8297-7E048280B511 wds:Q80976294-3C8B8015-9C97-4AD3-A32D-DD08A01759AF wds:Q80976294-3CD6D3F4-BC78-45B5-AEE2-E614E11008FB wds:Q80976294-4D595698-8196-4193-80B3-AF9B0A7B0B69 wds:Q80976294-5C8D8313-2A83-4BF4-A5FA-E9A5CD95B91B wds:Q80976294-62F32EDA-DDC0-4DC9-8019-BD197B93E196 wds:Q80976294-63EAF1F5-C1A8-4FE9-B093-ECC943A3E985 wds:Q80976294-65D6D0D9-0FAC-46E1-99AD-C6C685895850 wds:Q80976294-6EF153E2-C952-48A6-BA10-0BFDEDADAD29 wds:Q80976294-77671EAD-8E19-495D-A76D-5D8BE4AF6B7E wds:Q80976294-81726A4C-A4E9-477D-913C-5392B1700767 wds:Q80976294-97DB82F2-3767-4834-9D9E-DFFBCA78E314 wds:Q80976294-995D6CFF-3E91-4AE5-A63F-C7C3EBC12D56 wds:Q80976294-A58F6450-E772-4D1D-9267-EAB4C842503F wds:Q80976294-AD38B91A-B391-4AF9-8EE3-977B51E95BE2 wds:Q80976294-AE089826-372B-4343-97D2-09A6CD3B4902 wds:Q80976294-B9B4B153-A80E-40D8-B69B-BB786FB6D789 wds:Q80976294-BC604BF5-92C8-4CFF-B481-35395BC74A43 wds:Q80976294-BEF5933F-D2E8-4385-B486-22278609DFB1 wds:Q80976294-C91F1BC2-9479-45EE-BB18-D11C95818695 wds:Q80976294-D9E745D4-F03C-4B58-9A82-345CE555C253 wds:Q80976294-DCC50C69-B9A4-46F7-8DB1-A3F1FD54EAB9 wds:Q80976294-DD87A8DB-B375-4B84-B79B-F925A9BA6CAC wds:Q80976294-E19A721E-F2DD-439B-8CD0-8ED8B5C481EC wds:Q80976294-F212DFE1-359F-4481-ABEA-48749EFC4289 wds:Q80976294-F71642DF-7597-4C1F-99A5-EC859229DB8A wds:Q80976294-F731C715-51D5-45A6-AFAB-4E290607CCE1 wds:Q80976294-FE25F875-420D-4831-91F5-9C3A8C39B2D6
cites work	Rules for making human tumor cells PDX:PBX complexes are required for normal proliferation of pancreatic cells during development Nestin expression in pancreatic exocrine cell lineages. Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Cancer statistics, 2005 RAS oncogenes: the first 30 years. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line Association of human papillomavirus types 16 and 18 E6 proteins with p53. Ras-dependent activation of the small GTPase Ral. Creation of human tumour cells with defined genetic elements Telomerase catalytic subunit homologs from fission yeast and human The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation. Pancreatic carcinoma Cell migration and invasion assays Mammalian expression vectors for Ras family proteins: generation and use of expression constructs to analyze Ras family function Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes Ras family signaling: therapeutic targeting K-Ras promotes growth transformation and invasion of immortalized human pancreatic cells by Raf and phosphatidylinositol 3-kinase signaling Pancreatic cell lineage analyses in mice Human DNA methyltransferase gene DNMT1 is regulated by the APC pathway Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice DNA content and other factors associated with ten-year survival after resection of pancreatic carcinoma Immortalization with telomerase of the Nestin-positive cells of the human pancreas Notch 2-positive progenitors with the intrinsic ability to give rise to pancreatic ductal cells Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1 Telomerase activity does not always imply telomere maintenance Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma Genetic progression in the pancreatic ducts Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis. Nestin-expressing cells in the pancreatic islets of Langerhans Renewing the conspiracy theory debate: does Raf function alone to mediate Ras oncogenesis? Targeting signal transduction in pancreatic cancer treatment The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia Comparison of keratin monoclonal antibodies MAK-6, AE1:AE3, and CAM-5.2. Immortalized pancreatic duct cells in vitro and in vivo.
author name string	wds:Q80976294-29ABD313-F387-4BD3-B0B6-39D3C6866974 wds:Q80976294-42791D14-0DB2-4DE2-A677-62ED2E242165 wds:Q80976294-5DD91C32-2309-4C59-968F-122F367423B2 wds:Q80976294-B8323B44-4213-42FC-82BF-AA875526492D wds:Q80976294-C0CAA6C9-5288-4531-9EAF-F65D1B957447 wds:Q80976294-D87181B1-2E19-453C-9B0C-7D409E53D25F wds:Q80976294-F9D1394B-1CDF-4606-8012-E3B6D2D47897
author name string	Channing J Der Vladimir Khazak Paul M Campbell Angela L Groehler Michel M Ouellette Hong Jin Kim Kwang M Lee
rdfs:label	Ras-driven transformation of human nestin-positive pancreatic epithelial cells (en) Ras-driven transformation of human nestin-positive pancreatic epithelial cells (nl)

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