About: Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis

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About: Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 2007

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique (publié 2007) (fr) наукова стаття, опублікована в січні 2007 (uk) im Januar 2007 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 2007 (ast) artikull shkencor i botuar më 01 janar 2007 (sq) scientific article published on 01 January 2007 (en)
publication date	wds:Q80093460-80400E82-5749-46C4-8D38-16A338DE840B
publication date	2007-01-01 00:00:00Z (xsd:dateTime)
exact match	wds:Q80093460-92618F10-F229-453A-930B-1143380EBC8E
exact match	https://scigraph.springernature.com/pub.10.1038/nprot.2006.436
cites work	wds:Q80093460-05C57477-F0B7-418E-8565-73A49AAD19D1 wds:Q80093460-20F1E525-8694-450B-86C3-A2C47FFBA12D wds:Q80093460-25421AE9-BC66-4D89-A46A-C83A2C073378 wds:Q80093460-3F5BD076-7075-46E1-AF93-8E87FDEFBA65 wds:Q80093460-479CA520-4DCC-4B8C-8F60-B666B804677F wds:Q80093460-4D477C8D-DD90-49D5-B120-15B10E80A662 wds:Q80093460-5E4D1B94-6EE8-4903-8A53-CB21C0676775 wds:Q80093460-5FDD5020-6AC9-4F6D-9F78-B367368B74DB wds:Q80093460-6965F55E-873F-42B3-90AD-5CA445843742 wds:Q80093460-8F27A773-5CA8-4F59-984F-1F3C5F69BC13 wds:Q80093460-904D0E0B-28EB-4A7D-9122-5F562C89C294 wds:Q80093460-934C052A-942E-4C65-83E2-48FBCD87CBFB wds:Q80093460-978DEA8B-9D93-499A-A054-2635265B4879 wds:Q80093460-9F34E1CE-22F4-4540-8D4A-CD2BB1B90298 wds:Q80093460-B8D5C4EB-6D4B-474C-B916-556F91F33C3F wds:Q80093460-CC44860C-B9C0-46FB-BB55-2AC57000E58D wds:Q80093460-DC051D17-C588-472E-8BCF-5CECF6B11075
cites work	Inhibitors of mitotic kinesins: next-generation antimitotics Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5. Biologically active dihydropyrimidones of the Biginelli-type--a literature survey Highly enantioselective Biginelli reaction using a new chiral ytterbium catalyst: asymmetric synthesis of dihydropyrimidines Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen Controlled microwave heating in modern organic synthesis. Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5 Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton The impact of microwave synthesis on drug discovery. Microwave-enhanced and metal-catalyzed functionalizations of the 4-aryl-dihydropyrimidone template. Automated library generation using sequential microwave-assisted chemistry. Application toward the Biginelli multicomponent condensation. Building dihydropyrimidine libraries via microwave-assisted Biginelli multicomponent reactions. Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog. Synthesis and differential antiproliferative activity of Biginelli compounds against cancer cell lines: Monastrol, oxo-monastrol and oxygenated analogues A practical and green approach towards synthesis of dihydropyrimidinones: using heteropoly acids as efficient catalysts. Tunable carbon-carbon and carbon-sulfur cross-coupling of boronic acids with 3,4-dihydropyrimidine-2-thiones Combining synthetic and analytical strategies for preparative HPLC enantioseparation of monastrol racemic mixture
author name string	wds:Q80093460-AF532E3C-CBFE-4034-9AAD-4B5F64763C99
author name string	Doris Dallinger
rdfs:label	Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis (en) Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis (nl) Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis (sq)
skos:prefLabel	Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis (en) Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis (nl) Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis (sq)
name	Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis (en) Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis (nl) Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis (sq)
author	wds:Q80093460-1A6F39BA-CE4D-4899-8C53-33FB3D2C307F
author	C. Oliver Kappe
title	wds:Q80093460-D66E9613-7233-47A7-AEF2-669E5F3DDC30
title	Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis (en)
page(s)	wds:Q80093460-D7360DA5-533E-4043-9A62-931B92433F6B
page(s)	317-321
instance of	wds:Q80093460-CFD87951-24B0-40E1-807F-FE154FCF897C
instance of	scholarly article
main subject	wds:Q80093460-56E87BFF-9D7E-482D-ABD8-1ADB8C0BC022
main subject	microwave
PubMed ID	wds:Q80093460-A1106E39-34AC-4018-967D-A9B1B190894F
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17406591
PubMed ID	17406591
published in	wds:Q80093460-C7BF991D-EFC0-4D26-95DB-5C2B80D09EA6
published in	Nature Protocols
issue	wds:Q80093460-87CEF2E8-2CCE-4DED-AF0F-86632E7FF6C9
volume	wds:Q80093460-EE22BD6F-5942-4F56-B1C8-0B5753FA6F00
issue	2
volume	2
DOI	wds:Q80093460-E4064D25-A02F-4CE2-AE60-DD6A2D3E179B
DOI	http://dx.doi.org/10.1038/NPROT.2006.436
DOI	10.1038/NPROT.2006.436
Dimensions Publication ID	wds:Q80093460-80DE2533-6E34-4426-B417-33F0F7B6DEC6
Dimensions Publication ID	1023879673
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q80093460
is cites work of	Automated generation of a dihydropyrimidine compound library using microwave-assisted processing Irreversible Nek2 kinase inhibitors with cellular activity Raman spectroscopy as a tool for monitoring mesoscale continuous-flow organic synthesis: Equipment interface and assessment in four medicinally-relevant reactions Ammonium Trifluoroacetate-Mediated Synthesis of 3,4-dihydropyrimidin-2(1H)-ones Synthesis of alkyl- and aryl-amino-substituted anthraquinone derivatives by microwave-assisted copper(0)-catalyzed Ullmann coupling reactions Structure-activity relationships and molecular docking of novel dihydropyrimidine-based mitotic Eg5 inhibitors. A rapid and efficient route to benzazole heterocycles Kinesin-5 Eg5 is essential for spindle assembly and chromosome alignment of mouse spermatocytes
is cites work of	wds:Q33291321-8443C5DF-B54E-4362-8BB2-A316989D2321 wds:Q37156888-805EF655-5BF9-4F9E-99B8-179BB46B030D wds:Q42844160-5187E8FF-A0CF-4791-A98C-C3487C653F3D wds:Q43079085-7CACD027-C492-45E3-A3B6-C29BAC5A381F wds:Q53304319-F4066F79-4112-41C6-8FDC-185EA6867174 wds:Q39533198-32683B25-3BA2-4271-9AC2-AD050B8A6073 wds:Q37186154-F5548F41-8E5B-4A2A-B776-DCCB819BBFCE wds:Q90284006-C60B6FAC-B3DC-48CD-9C75-3E2DA4B8D6D6

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