About: tumor initiation

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first phase in tumor development

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rdf:type	Item
owl:sameAs	tumor initiation
description	first phase in tumor development (en)
rdfs:label	tumor initiation (en) ابتداء الورم (ar) 発がんイニシエーション (ja)
skos:prefLabel	tumor initiation (en) ابتداء الورم (ar) 発がんイニシエーション (ja)
name	tumor initiation (en) ابتداء الورم (ar) 発がんイニシエーション (ja)
Freebase ID	wds:Q7852676-1E1873B9-0FEC-4F05-BA4F-96905514AE38
Freebase ID	/m/03qp87r
OpenAlex ID	wds:Q7852676-7E19CBA6-7BFC-47C5-9247-6EC8392CC06F
Microsoft Academic ID	wds:Q7852676-DFABADB0-310D-4A23-8CE2-293AD4C81595
Microsoft Academic ID	https://makg.org/entity/2778287671
OpenAlex ID	C2778287671
Microsoft Academic ID	2778287671
is about of	tumor initiation https://www.wikidata.org/wiki/Special:EntityData/Q7852676 Tumor initiation https://ar.wikipedia.org/wiki/%D8%A7%D8%A8%D8%AA%D8%AF%D8%A7%D8%A1_%D8%A7%D9%84%D9%88%D8%B1%D9%85
is main subject of	Inhibitory effect of topical application of a green tea polyphenol fraction on tumor initiation and promotion in mouse skin Prostaglandins and cancer: A review of tumor initiation through tumor metastasis LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer The role of chromosomal instability in tumor initiation Tumor initiation and progression in hepatocellular carcinoma: risk factors, classification, and therapeutic targets Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: effect on tumor initiation and angiogenesis The DACH/EYA/SIX gene network and its role in tumor initiation and progression MYC-y mice: from tumour initiation to therapeutic targeting of endogenous MYC. Fish Oil Enhances Targeted Apoptosis During Colon Tumor Initiation in Part by Downregulating Bcl-2 Oral administration of the citrus coumarin, isopimpinellin, blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene in SENCAR mice Haploinsufficiency in the prometastasis Kiss1 receptor Gpr54 delays breast tumor initiation, progression, and lung metastasis Perforin and interferon-gamma activities independently control tumor initiation, growth, and metastasis. Mechanisms of embryonal tumor initiation: distinct roles for MycN expression and MYCN amplification. An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth. Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation Peroxyl free radicals: potential mediators of tumor initiation and promotion Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH-DNA binding and metabolic activation of carcinogenic PAH in mouse epidermis Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation Inhibition of redox/Fyn/c-Cbl pathway function by Cdc42 controls tumour initiation capacity and tamoxifen sensitivity in basal-like breast cancer cells Collagen density promotes mammary tumor initiation and progression Bacterial Attachment to a Specific Wound Site as an Essential Stage in Tumor Initiation by Agrobacterium tumefaciens An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer. Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras mTORC1-mediated translational elongation limits intestinal tumour initiation and growth Mesenchymal stem cells cancel azoxymethane-induced tumor initiation. The role of focal adhesion kinase in tumor initiation and progression. Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine. Defining stem cell dynamics in models of intestinal tumor initiation. The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo The in vitro spheroid melanoma cell culture assay: cues on tumor initiation? VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation BCCIP suppresses tumor initiation but is required for tumor progression THE INFLUENCE OF SOME IRRITANT CHEMICALS AND SCARIFICATION ON TUMOUR INITIATION BY URETHANE IN MICE. Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy Polyclonal tumors in the mammalian intestine: are interactions among multiple initiated clones necessary for tumor initiation, growth, and progression? RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis Loss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoid CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation. Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation Id2 mediates tumor initiation, proliferation, and angiogenesis in Rb mutant mice. Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma. A radical role for p38 MAPK in tumor initiation Mouse skin is particularly susceptible to tumor initiation during early anagen of the hair cycle: possible involvement of hair follicle stem cells. Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer Thermal studies on the factors responsible for tumor initiation in crown gall E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling NKG2D function protects the host from tumor initiation Pten null prostate epithelium promotes localized myeloid-derived suppressor cell expansion and immune suppression during tumor initiation and progression The potential role of COX-2 in cancer stem cell-mediated canine mammary tumor initiation: an immunohistochemical study Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation. 2-difluoromethylornithine and dehydroepiandrosterone inhibit mammary tumor progression but not mammary or prostate tumor initiation in C3(1)/SV40 T/t-antigen transgenic mice STX140, but not paclitaxel, inhibits mammary tumour initiation and progression in C3(1)/SV40 T/t-antigen transgenic mice The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation Formation of depurinating N3adenine and N7guanine adducts after reaction of 1,2-naphthoquinone or enzyme-activated 1,2-dihydroxynaphthalene with DNA. Implications for the mechanism of tumor initiation by naphthalene. Live imaging of innate immune cell sensing of transformed cells in zebrafish larvae: parallels between tumor initiation and wound inflammation TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis An integrin-linked machinery of cytoskeletal regulation that enables experimental tumor initiation and metastatic colonization Multiple cell death pathways as regulators of tumour initiation and progression. Speculations on the roles of RB1 in tissue-specific differentiation, tumor initiation, and tumor progression. Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice DEK oncoprotein regulates transcriptional modifiers and sustains tumor initiation activity in high-grade neuroendocrine carcinoma of the lung Obesity and colorectal cancer: role of adipokines in tumor initiation and progression Antibody against CD44s inhibits pancreatic tumor initiation and postradiation recurrence in mice. Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma Mitochondrial DNA in Tumor Initiation, Progression, and Metastasis: Role of Horizontal mtDNA Transfer Lipocalin 2 performs contrasting, location-dependent roles in APCmin tumor initiation and progression Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Poli gene as a candidate for Par2.

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