About: Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens

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About: Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens Goto Sponge NotDistinct Permalink

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scientific article published on 01 December 1998

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 1998 (uk) article scientifique publié en 1998 (fr) im Dezember 1998 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 1998 (ast) scientific article published on 01 December 1998 (en)
publication date	wds:Q77620066-D05FF615-111F-4A1D-BC87-5610F39C3200
publication date	1998-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q77620066-E57B350F-1D97-42E4-A272-1E3178B6D92B
language of work or name	English
author name string	wds:Q77620066-3D08E625-7B9A-4FA5-9B49-C0176C4657D6 wds:Q77620066-6734FDC4-D289-4E13-9871-0153AC77EBE5 wds:Q77620066-7F033FDC-234F-47AA-8A20-4F568B59D092 wds:Q77620066-B0C0573A-2F96-418F-AA4F-3DF370632183
author name string	Domínguez O Foz-Sala M Sospedra M Ferrer-Francesch X
rdfs:label	Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens (en) Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens (nl)
skos:prefLabel	Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens (en) Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens (nl)
name	Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens (en) Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens (nl)
author	wds:Q77620066-A9AE4E07-CDAA-4F81-ABC7-0A74B25DE3A6 wds:Q77620066-F21AB64E-63E6-41CF-94F4-95C2B570454A
author	Manel Juan R Pujol-Borrell
title	wds:Q77620066-B69BA5C8-9E30-4989-81B4-C967F4479E12
title	Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens (en)
page(s)	wds:Q77620066-FDE9CB0F-2908-4365-9BB3-94703AF34FDD
page(s)	5918-5929
instance of	wds:Q77620066-B0D06210-AA7A-44D9-BF83-25686481531D
instance of	scholarly article
PubMed ID	wds:Q77620066-6BFD2FEE-170A-4F6F-8704-246CCAE105D9
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9834072
PubMed ID	9834072
published in	wds:Q77620066-686161BF-89BE-45BD-AC12-001D34470F3F
published in	Journal of Immunology
issue	wds:Q77620066-4DCB3BE7-CECE-4813-8A24-31B5B33B8BD7
volume	wds:Q77620066-042A3A50-7A46-47B9-87A7-1DAFF85E2C64
issue	11
volume	161
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q77620066
is cites work of	Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitus Thyroid autoimmune disease: demonstration of thyroid antigen-specific B cells and recombination-activating gene expression in chemokine-containing active intrathyroidal germinal centers Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue Onset of promiscuous gene expression in murine fetal thymus organ culture. Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity CD8(+) T-cell autoreactivity to an HLA-B27-restricted self-epitope correlates with ankylosing spondylitis Thymic expression of peripheral tissue antigens in humans: a remarkable variability among individuals Persistent degenerative changes in thymic organ function revealed by an inducible model of organ regrowth. The role of the thymus in tolerance Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity Central and peripheral autoantigen presentation in immune tolerance High-avidity autoreactive CD4+ T cells induce host CTL, overcome T(regs) and mediate tumor destruction Peripheral antigen-expressing cells in type 1 diabetes Studies in mice deficient for the autoimmune regulator (Aire) and transgenic for the thyrotropin receptor reveal a role for Aire in tolerance for thyroid autoantigens "Persistence of Diabetes" - Why Has Research into Type 1 Diabetes not Made Significant Advances? Incidentally Visualization of the Thymus on Whole-Body Iodine Scintigraphy: Report of 2 Cases and Review of the Latest Insights Absence of some common organ-specific and non-organ-specific autoimmunity in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy Age-related deregulation of Aire and peripheral tissue antigen genes in the thymic stroma of non-obese diabetic (NOD) mice is associated with autoimmune type 1 diabetes mellitus (DM-1). Regulation of TSHR Expression in the Thyroid and Thymus May Contribute to TSHR Tolerance Failure in Graves' Disease Patients via Two Distinct Mechanisms Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells Programming of neuroendocrine self in the thymus and its defect in the development of neuroendocrine autoimmunity Proinsulin is encoded by an RNA splice variant in human blood myeloid cells. The cross-regulatory relationship between human dendritic and regulatory T cells and its role in type 1 diabetes mellitus Twenty Years of AIRE. Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ cultures Replenishing Peripheral CD4(+) Regulatory T Cells: A Possible Immune-Intervention Strategy in Type 1 Diabetes? Hyperplastic thymus with increased angiogenesis is correlated with elevated serum thyroglobulin level in differentiated thyroid cancer patients with TENIS syndrome. The presentation of neuroendocrine self-peptides in the thymus: an essential event for individual life and vertebrate survival
is cites work of	wds:Q33630981-B613B0E0-C4A9-4E73-9647-DAC5FCE401F6 wds:Q35702560-1D471109-FFDB-412E-8E0C-4DF4BFBF3EA6 wds:Q35688768-E5A98B07-8EB2-474F-B79A-689B78B579C8 wds:Q36924530-C1091EF8-757C-45C1-8CEF-033730F7F713 wds:Q35721612-6EBA5ED1-4AE4-47DE-9845-C5174788E4D9 wds:Q37355703-E9EDFA41-9A12-4AF4-A231-830771F7A87C wds:Q28084230-8A05325D-F794-43AA-81B7-407A95096068 wds:Q37837965-EA30D6B5-C1C4-4DC6-A1BE-314482F26829 wds:Q92405227-F6860505-F1B8-4F94-9A1D-47920F516BBE wds:Q38153686-A5171481-9000-43C9-BF04-673AE9F132D0 wds:Q39711541-B931F1C1-168A-4682-BEF4-D9CF144DEC51 wds:Q40432095-45EE6F0C-4B08-4F4D-BBB1-6DB829D5E24E wds:Q42281307-30134E36-430C-49DA-94E9-19489CE2080F wds:Q28359868-C03F9794-57B5-41DD-A9FF-26BC7728E6DC wds:Q34103905-46370ED7-83D7-4FEF-9C4F-0273B37571A6 wds:Q37210756-88722578-A0C1-4D71-99C9-32E946999178 wds:Q34350303-64917871-E487-490C-A0ED-05D1EE00B994 wds:Q36399327-7FAB688E-D532-4A8E-9B36-E11994BCA525 wds:Q35102415-17D5F524-7A23-4CE9-BEAF-211782BF7938 wds:Q36084610-C3BA9089-484A-4E0B-BD9E-B261FD75E25B wds:Q34025467-5222E3E9-141B-4DD5-8644-6DDB442F41D6 wds:Q35694446-052A3102-167F-43B4-B91E-713E43E1271B wds:Q44327053-F6B9C109-725B-4FA7-82C0-E6BA54727AFC

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