About: Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

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About: Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice Goto Sponge NotDistinct Permalink

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scientific article published on 01 October 1998

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в жовтні 1998 (uk) article scientifique publié en 1998 (fr) im Oktober 1998 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'ochobre de 1998 (ast) scientific article published on 01 October 1998 (en)
publication date	wds:Q77470803-D49C4D56-D781-41EC-947B-CCB8D8ECB254
publication date	1998-10-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q77470803-734236C9-78C1-4925-8256-7A9C84755A23
language of work or name	English
cites work	wds:Q77470803-03AAAAC9-0519-48D2-8FC9-96527F7E6F6B wds:Q77470803-06B4E50C-1013-4A45-8161-6FFB0401CD26 wds:Q77470803-1107ED31-CF8C-483B-B827-4E8C867049C2 wds:Q77470803-15F1E34E-99A0-49C2-B23D-44B23A655949 wds:Q77470803-1B7D5043-9D5D-4028-836E-8945E364FA70 wds:Q77470803-1C9ABDF2-C4C8-4D95-B7F7-3017B1771DBA wds:Q77470803-2B4A67A1-1491-45A0-B22A-5470F47861DF wds:Q77470803-30729408-A888-4367-BFA1-7FBB59F1AECD wds:Q77470803-35EE01A7-DB5F-47CF-9101-C4A6B77EA9AF wds:Q77470803-391278DF-C4CB-457F-8F4A-45E4501495F1 wds:Q77470803-473FBDB4-1AA0-4826-8144-644F44335B60 wds:Q77470803-545D7E6A-7750-4BDD-8E82-60E0CD3B6254 wds:Q77470803-55185153-EFD2-414B-8956-70D7CD75461D wds:Q77470803-6949AFDF-64F3-469F-B10A-D82118520CAC wds:Q77470803-6AB4377C-E3DE-4101-B1D8-13966C55941C wds:Q77470803-7E5C5092-333B-4955-A80B-7AC34B513D54 wds:Q77470803-830A0CBD-E83E-45AD-B296-9F02D0C8AC76 wds:Q77470803-8D6E437F-8904-4FE7-B94E-716B2BDC2D6F wds:Q77470803-939CE446-FF25-4A24-B7A9-13590B59E860 wds:Q77470803-98BAF999-E15F-4CEF-BA0D-A9C373AC3EF2 wds:Q77470803-99E9D0D5-4368-4F23-89EC-A281A7A0B3D3 wds:Q77470803-9B33886E-76AA-4143-9ABB-1C5E125E9A54 wds:Q77470803-B19350DE-818A-44AE-AB15-7703C1B95D49 wds:Q77470803-BF0E09C1-3FF3-488C-8872-B4B2B5DAB328 wds:Q77470803-C14609B4-9C0C-4873-973A-C5DBE729F6F2 wds:Q77470803-CF9925D0-52AD-4CE8-9467-1ACE4E856398 wds:Q77470803-D830C8FC-1EE1-4C15-9DEB-A14CA8C5D785 wds:Q77470803-F0721037-3536-4893-AED8-9292B04AA8E1 wds:Q77470803-F0B35555-D104-4052-9136-441599864B91 wds:Q77470803-FA866C2C-9ADE-4322-8F45-FFCE4D00B1C0
cites work	Induction of cell differentiation by human immunodeficiency virus 1 vpr. Neurological complications of HIV infection Construction and in vitro properties of HIV-1 mutants with deletions in "nonessential" genes Serine phosphorylation-independent downregulation of cell-surface CD4 by nef Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection Importance of the nef gene for maintenance of high virus loads and for development of AIDS Signal transduction by lymphocyte antigen receptors Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration. Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages From negative factor to a critical role in virus pathogenesis: the changing fortunes of Nef. The pharmacology of T cell apoptosis Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity New concepts in the immunopathogenesis of HIV infection Survival from early, intermediate, and late stages of HIV infection Transgenic models of HIV-1. Cardiomyopathy and other symptomatic heart diseases associated with HIV infection. The majority of cells infected with the defective murine AIDS virus belong to the B-cell lineage Viral counts count in HIV infection Acquired immunodeficiency syndrome and the kidney Specific expression of the human CD4 gene in mature CD4+ CD8- and immature CD4+ CD8+ T cells and in macrophages of transgenic mice Vacuolar myelopathy in transgenic mice expressing human immunodeficiency virus type 1 proteins under the regulation of the myelin basic protein gene promoter
author name string	wds:Q77470803-3985C462-35D2-4EF6-8F02-5BBA3FF7EDB4 wds:Q77470803-6A3FCCC9-5E9F-4B89-B648-80EAC159049F wds:Q77470803-75196DCA-B11B-4C05-B6E1-284C40A755F1 wds:Q77470803-7E526B5F-6F8C-4BC1-A8D5-32B10D12BED6 wds:Q77470803-C4C15E5C-B39F-4B70-B19A-DE83B3168870 wds:Q77470803-EA1E1FBB-43E8-40A2-AA8F-B0E31E0220C7
author name string	P Jolicoeur S Jothy A Guimond D G Kay N Rebai Z Hanna
rdfs:label	Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice (en) Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice (nl)
skos:prefLabel	Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice (en) Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice (nl)
name	Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice (en) Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice (nl)
title	wds:Q77470803-78AB761C-406D-44F1-9D38-D62436EB0CA6
title	Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice (en)
page(s)	wds:Q77470803-A1674E02-A8B7-465F-BFCC-A1EFE9E3EDEE
page(s)	163-175
instance of	wds:Q77470803-AA029E8B-D1B5-4B4E-A481-DFB99BD85BE4
instance of	scholarly article
main subject	wds:Q77470803-96DD3FD9-5E79-4AB5-97F6-1153DC7F8BF2
main subject	HIV
PubMed ID	wds:Q77470803-F77A98BA-4434-4EF4-8EC5-D9ED1A02017C
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9790524
PubMed ID	9790524

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