About: organophosphonate

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carbon-containing phosphonic acid compounds

Attributes	Values
rdf:type	Item
description	carbon-containing phosphonic acid compounds (en)
rdfs:label	organophosphonate (en)
skos:prefLabel	organophosphonate (en)
name	organophosphonate (en)
instance of	wds:Q76636048-f66fa159-48ae-8b6a-3bba-769d298b9a16
instance of	structural class of chemical entities
subclass of	wds:Q76636048-5fd55cf6-4b83-db48-c70c-1757bba2c462 wds:Q76636048-cc3defc8-4139-6058-35e4-bc8d523739d3
subclass of	phosphonate organic compound
skos:altLabel	organophosphonates (en)
UMLS CUI	wds:Q76636048-0C6C2F9A-ABD5-4F75-A19A-E78B3B0C31BA
MeSH descriptor ID	wds:Q76636048-ABADFF15-9D7D-44A9-95E7-8D62C4B0A306
MeSH tree code	wds:Q76636048-3ee68c95-4e66-1f8f-a68e-beb864e84e33
MeSH descriptor ID	http://id.nlm.nih.gov/mesh/D063065
MeSH tree code	http://id.nlm.nih.gov/mesh/D02.705.429
UMLS CUI	C0260127
MeSH descriptor ID	D063065
MeSH tree code	D02.705.429
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q76636048
is subclass of of	azophosphonate organothiophosphonates organofluorophosphonates
is subclass of of	wds:Q794027-4047ce47-4cec-4307-c9ae-f2af3132a228 wds:Q76620358-2c1e1e72-47a4-466f-2bb3-017c44a4cc8e wds:Q76625546-42407ab5-4def-ac3b-49bd-a4f6209151ad
is main subject of	Suppression of HBV by tenofovir in HBV/HIV coinfected patients: a systematic review and meta-analysis The enzymic cleavage of the carbon-phosphorus bond: Purification and properties of phosphonatase Hydrolysis of phosphonate esters catalyzed by 5'-nucleotide phosphodiesterase Chemotherapy of feline immunodeficiency virus infection Treatment of murine cytomegalovirus infections in severe combined immunodeficient mice with ganciclovir, (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, interferon, and bropirimine Synthesis of DNA/RNA and their analogs via phosphoramidite and H-phosphonate chemistries Studies on reaction conditions for ribonucleotide synthesis via the H-phosphonate approach Clinical utility of entecavir for chronic hepatitis B in Chinese patients Synthetic Procedures Leading towards Aminobisphosphonates Correlation of 3,4-dihydroxybutyl 1-phosphonate resistance with a defect in cardiolipin synthesis in Escherichia coli Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages Ligand-induced conformational changes in acetylcholinesterase investigated with fluorescent phosphonates PHOSPHONOLIPIDS. I. SYNTHESIS OF A PHOSPHONIC ACID ANALOGUE OF CEPHALIN Phosphonic acid analogues of carbohydrate metabolites. Dihydroxypropylphosphonic acid. II. Substrate specificity of L-glycerol-3-phosphate : NAD oxidoreductase Lamivudine plus adefovir combination therapy versus entecavir monotherapy for lamivudine-resistant chronic hepatitis B: a systematic review and meta-analysis Alkaline phosphatase: affinity chromatography and inhibition by phosphonic acids Cytomegalovirus in hematopoietic stem cell transplant recipients: current status, known challenges, and future strategies Comparative activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against rat cytomegalovirus infection in vitro and in vivo (S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine in the therapy of thymidine kinase-positive and -deficient herpes simplex virus experimental keratitis Intracellular metabolism of the antiherpes agent (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine Arrangement of the phosphate- and metal-binding subsites of phosphoglucomutase. Intersubsite relations by means of inhibition patterns Comparison of efficacy and safety of tenofovir and entecavir in chronic hepatitis B virus infection: a systematic review and meta-analysis Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine Enzymic hydrolysis of phosphonate esters Targeted therapy of human immunodeficiency virus‐related disease A review of the virological efficacy of the 4 World Health Organization-recommended tenofovir-containing regimens for initial HIV therapy Efficacy of Multiple- or Single-Dose Cidofovir against Vaccinia and Cowpox Virus Infections in Mice Distributions of several agents useful in imaging myocardial infarcts Model studies for the reactivation of aged phosphonylated acetylcholinesterase. Use of alkylating agents containing nucleophilic groups Clinical Potential of the Acyclic Nucleoside Phosphonates Cidofovir, Adefovir, and Tenofovir in Treatment of DNA Virus and Retrovirus Infections Efficacy and resistance in de novo combination lamivudine and adefovir dipivoxil therapy versus entecavir monotherapy for the treatment-naive patients with chronic hepatitis B: a meta-analysis A COMPARISON OF THE SPECIFICITY OF INHIBITION BY PHOSPHONATE ESTERS OF THE FIRST COMPONENT OF COMPLEMENT AND THE ANTIGEN-INDUCED RELEASE OF HISTAMINE FROM GUINEA PIG LUNG Enzymic hydrolysis of phosphonate esters. Reaction mechanism of intestinal 5'-nucleotide phosphodiesterase Synthesis and enzymatic properties of deoxyribooligonucleotides containing methyl and phenylphosphonate linkages First-line treatment of chronic hepatitis B with entecavir or tenofovir in 'real-life' settings: from clinical trials to clinical practice Isolation and Identification of 2-Aminoethyl-phosphonic Acid from Bovine Brain Distribution and Fate of 2-Aminoethylphosphonic Acid in Tetrahymena Experimental examinations on the suitability of organoaminomethane-bis-phosphonic acids for bone-scintigraphy by means of Tc-99m in animals α-Hydroxyphosphonate Oligonucleotides: A Promising DNA Type? Early detection of hepatitis B drug resistance: implications for patient management Pharmacokinetics in mice of the anti-retrovirus agent 9-(2-phosphonylmethoxyethyl)adenine Synthesis of nucleoside phosphate and phosphonate prodrugs A substrate-induced conformation change in the reaction of alkaline phosphatase from Escherichia coli Preparation of immunologically responsive liposomes with phosphonyl and phosphinyl analogs of lecithin Local and systemic effects of intralaryngeal injection of cidofovir in a canine model UTILIZATION OF CARBON-BOUND PHOSPHORUS BY MICROORGANISMS 31P NMR of phosphate and phosphonate complexes of metalloalkaline phosphatases The Kabachnik-Fields reaction: mechanism and synthetic use. Efficacy of CMX001 as a prophylactic and presymptomatic antiviral agent in New Zealand white rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans Transient early post‐inoculation anti‐retroviral treatment facilitates controlled infection with sparing of CD4+ T cells in gut‐associated lymphoid tissues in SIVmac239‐infected rhesus macaques, but not resistance to rechallenge Localized Fluoride Release from Fluorine-carrying Polyphosphonates Meta-analysis: adefovir dipivoxil in combination with lamivudine in patients with lamivudine-resistant hepatitis B virus The acyclic nucleoside analogue penciclovir is a potent inhibitor of equine herpesvirus type 1 (EHV-1) in tissue culture and in a murine model Side-effects of cidofovir in the treatment of recurrent respiratory papillomatosis Affinity elution from a phosphonic acid-sepharose derivative in the purification of human liver alkaline phosphatase Technetium-99m-diphosphonate accumulation in amyloid Evaluation of 9-(2-phosphonylmethoxyethyl) adenine therapy for feline immunodeficiency virus using a quantitative polymerase chain reaction Decreased reactivity of organophosphorus inhibitors towards a modified chymotrypsin Arrangement of the phosphate- and metal-binding subsites of phospholucomutase. Intersubsite distance by means of nuclear magnetic resonance measurements Kinetics of the Addition of Diethyl Phosphonate to Various p-Substituted Benzylideneanilines Synthesis of Peptides Contahng Aminophosphonic Acids Determination of antiviral efficacy against lymphotropic herpesviruses utilizing flow cytometry Diphosphonates. Experimental and clinical aspects Adsorption of a Polyphosphonate on Bovine Enamel and Hydroxyapatite Ageing and dealkylation of soman (pinacolylmethylphosphonofluoridate)-inactivated eel cholinesterase Inhibition of acetylcholinesterase by the enantiomers of isopropyl S-2-trimethylammonioethyl methylphosphonothioate iodide. Affinity and phosphorylation constants Determination of 9-[(2-phosphonylmethoxy)ethyl]adenine in rat urine by high-performance liquid chromatography with fluorescence detection Treatment advances for CMV retinitis Efficacy of CMX001 as a post exposure antiviral in New Zealand White rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans Effects of 2-pyridinium aldoxine methochloride and atropine in relation to elevation of blood pH in soman-poisoned dogs Lack of retinal toxicity of the anticytomegalovirus drug (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine Regression of a cutaneous melanoma metastasis after intralesional cidofovir The relationship of the structure of phosphonate esters to their ability to inhibit chymotrypsin, trypsin, acetylcholinesterase and C′ia

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