About: Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction

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About: Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction Goto Sponge NotDistinct Permalink

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scientific article published on 01 August 2001

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 2001 (uk) مقالة علمية تنشرت ف 1 غشت 2001 (ary) article scientifique publié en 2001 (fr) im August 2001 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'agostu de 2001 (ast) scientific article published on 01 August 2001 (en)
publication date	wds:Q74403380-653EB494-ACBF-4628-858A-845DBAB6809A
publication date	2001-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q74403380-E350714E-5044-4C2D-9ECC-2385AD23AB15
language of work or name	English
cites work	wds:Q74403380-03F456AA-2AF2-4F14-BB7F-BA8B70CEE4E3 wds:Q74403380-1880A1A6-23F8-4A2F-B9E6-A63C43EDC79D wds:Q74403380-18BD306E-6505-409F-B49E-7E2F1D461727 wds:Q74403380-1C690E12-289E-4672-97F1-8814C09B6F41 wds:Q74403380-2D434533-6F22-42EE-8614-34377BB3C3F2 wds:Q74403380-3BD3D6B7-E0E2-4FA7-9309-68CFD90D9BA8 wds:Q74403380-49700E53-766E-4237-A1B9-B29DA28345F2 wds:Q74403380-4DB00C60-86F4-4955-80A1-E85C2839F595 wds:Q74403380-6ED4D497-45EC-4F8B-B91E-6FB474BE28F4 wds:Q74403380-6F209D51-5F80-4E9D-ADC1-6748B0C3EECA wds:Q74403380-8522F78E-C9DC-4A03-B5B5-B6C499A72171 wds:Q74403380-9D97E069-0528-4AFD-A182-A8E2D6506AAE wds:Q74403380-C195FE24-8342-46C6-8937-39A18C406ECA wds:Q74403380-D85EE927-BCFD-42CF-924C-B045ACC6778D wds:Q74403380-ED8409B5-8C67-469C-9094-71551D16A2F4
cites work	Mdm2 promotes the rapid degradation of p53 Regulation of p53 stability by Mdm2 1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling additive The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation Molecular characterization of the hdm2-p53 interaction Detecting protein function and protein-protein interactions from genome sequences Amplification of a gene encoding a p53-associated protein in human sarcomas The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53 Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line Trojan peptides: the penetratin system for intracellular delivery. Racemization studies during solid-phase peptide synthesis using azabenzotriazole-based coupling reagents New coupling reagents in peptide chemistry Chalcone derivatives antagonize interactions between the human oncoprotein MDM2 and p53. A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines
author name string	wds:Q74403380-07423B7F-2D7D-4A67-BE5C-35E243969CD1 wds:Q74403380-27DC8686-A053-4BEB-AC5C-B5A992971868 wds:Q74403380-E2F86144-D5E2-48AB-B87B-11919B4BB1C4
author name string	C García-Echeverría P Furet P Chène
rdfs:label	Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction (en) Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction (nl)
skos:prefLabel	Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction (en) Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction (nl)
name	Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction (en) Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction (nl)
title	wds:Q74403380-1A00FBC9-3D2B-46F6-A192-146CBE0A8026
title	Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction (en)
page(s)	wds:Q74403380-9B21A323-C83F-4E4C-91BD-31F98F601818
page(s)	2161-2164
instance of	wds:Q74403380-65935548-B2E0-4C29-BC4F-34A0B8048FD2
instance of	scholarly article
main subject	wds:Q74403380-8A09536A-E0DF-44FF-A959-6BC25910266C
main subject	protein-protein interaction
PubMed ID	wds:Q74403380-D33E6974-E263-44CB-B04A-A6A5A98137C7
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11514160
PubMed ID	11514160
published in	wds:Q74403380-B75AE595-0EDF-4344-8F32-2CE74BEE56E1
published in	Bioorganic & Medicinal Chemistry Letters
issue	wds:Q74403380-AF921DC7-765E-4667-ACB2-234B23E1EA8A
volume	wds:Q74403380-A45075FF-CF49-4CC1-8AE0-F6F9A7497C9A
issue	16
volume	11
number of pages	wds:Q74403380-04FA0005-4E8E-4846-9FA2-554FCF24D582
number of pages	4 (xsd:decimal)
DOI	wds:Q74403380-3C3C9C79-B8C5-41DD-BA77-003B605D381F
DOI	http://dx.doi.org/10.1016/S0960-894X(01)00394-8
DOI	10.1016/S0960-894X(01)00394-8
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q74403380
is cites work of	PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo The penetratin sequence in the anticancer PNC-28 peptide causes tumor cell necrosis rather than apoptosis of human pancreatic cancer cells Targeting the p53-MDM2 interaction to treat cancer beta-Homolysine oligomers: a new class of Trojan carriers
is cites work of	wds:Q23915398-2DC2A4D4-AC28-44D0-BBDA-1E1659E8C9AB wds:Q40683524-71A27860-5874-4AC6-A9E9-3D8098F07820 wds:Q23923633-49981E02-5221-47CF-A058-83013CBA2DD5 wds:Q35903526-FA29EA96-41E7-42F7-AC21-C3EB5E0971D0

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