About: Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific article published on 01 September 2000

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована у вересні 2000 (uk) article scientifique publié en 2000 (fr) im September 2000 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en setiembre de 2000 (ast) scientific article published on 01 September 2000 (en)
publication date	wds:Q74315115-AB25B472-2F54-4BEF-930C-6B4F16019431
publication date	2000-09-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q74315115-B514095E-3AE5-48E7-A6B0-3DF9D040BD25
language of work or name	English
cites work	wds:Q74315115-01C8D037-684C-40CA-9BED-ED264923AC3F wds:Q74315115-209EF2C4-7DF9-41AB-BECC-DEE1AC08F227 wds:Q74315115-2E263CAD-0CFF-409F-8D25-4D3F30890696 wds:Q74315115-36EBAD29-F390-420C-8B5B-4E0E704A3371 wds:Q74315115-417A95A9-6DB0-4D4E-82C2-A979523C8D0D wds:Q74315115-4384D06F-2556-4FBF-AC29-CA85C8FFDA4A wds:Q74315115-A1C93A56-A6BD-4B0D-A866-630873C41800 wds:Q74315115-BC0A300C-8EA3-419C-804C-E9864BFC87D1
cites work	Current and potential drugs for treatment of obesity Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction Obesity A review of central 5-HT receptors and their function 5-HT2C receptor activation decreases appetite and body weight in obese subjects Potencies of antagonists indicate that 5-HT1C receptors mediate 1-3(chlorophenyl)piperazine-induced hypophagia Orlistat, a new lipase inhibitor for the management of obesity Clozapine. A review of its pharmacological properties, and therapeutic use in schizophrenia
author name string	wds:Q74315115-0071AB9E-2414-4ECE-961C-774401F558F1 wds:Q74315115-217FC157-DEF1-4B52-8E61-CA7A272BDD31 wds:Q74315115-7097560A-2B45-4711-A855-D2857624B772 wds:Q74315115-7C7CD127-F57E-4B10-887D-30CE77B0D639 wds:Q74315115-86407858-6D80-469C-9464-5A0CDB1A0C4C wds:Q74315115-8ABC3E8E-1FF1-401B-BFB1-F343D9CC46CE wds:Q74315115-A9CDB60E-1BF8-44EB-B8B6-68085075B9AE wds:Q74315115-ABF4F2CE-D92F-415F-9687-D1AC45271C0D wds:Q74315115-BF7E9986-F2BD-49A9-8A48-045FFE7D769E wds:Q74315115-DBCBFDF0-D773-4658-8D60-F1B113924175 wds:Q74315115-E3D0B2EF-A459-42CA-9622-259B168AF6BC wds:Q74315115-F551EC80-1454-4010-9FAA-97378F07FC91 wds:Q74315115-F946246C-E9EB-4875-A9A2-4B519C684421
author name string	Y Zhang H Mazandarani J Coupet J A Nelson J Dunlop M Kagan D Graziano S Rosenzweig-Lipson S Sukoff A L Sabb G S Welmaker J E Sabalski J R Potoski
rdfs:label	Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines (en) Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines (nl)
skos:prefLabel	Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines (en) Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines (nl)
name	Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines (en) Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines (nl)
title	wds:Q74315115-616FADBF-C3BD-42C8-8213-C6F1957C8BEA
title	Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines (en)
page(s)	wds:Q74315115-394D22D7-3743-4C87-BD9B-091B9051360B
page(s)	1991-1994
instance of	wds:Q74315115-8C8D6389-E25D-4252-9DEA-CEE2C70F486B
instance of	scholarly article
PubMed ID	wds:Q74315115-D571C171-F2EE-4574-867E-4A5303D7BB29
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10987434
PubMed ID	10987434
published in	wds:Q74315115-7D72E8D3-0DCB-4BA4-84B0-AFDD1388BFB1
published in	Bioorganic & Medicinal Chemistry Letters
issue	wds:Q74315115-F13C61F7-0781-4749-8E22-270C817EB21F
volume	wds:Q74315115-6465454A-8839-4900-BD3D-5D7F703036F2
issue	17
volume	10
number of pages	wds:Q74315115-4245B89F-6D0F-48B1-B9FE-794725733164
number of pages	4 (xsd:decimal)
DOI	wds:Q74315115-E56C7430-88EE-430A-8A39-FC32FA53E583
DOI	http://dx.doi.org/10.1016/S0960-894X(00)00400-5
DOI	10.1016/S0960-894X(00)00400-5
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q74315115
is cites work of	Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents Regulation of adipocyte differentiation by activation of serotonin (5-HT) receptors 5-HT2AR and 5-HT2CR and involvement of microRNA-448-mediated repression of KLF5 Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis Innovative approaches for the development of antidepressant drugs: current and future strategies Selective 5-hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: identification of drugs with antidepressant-like action Pharmacological profile of the 5-HT(2C) receptor agonist WAY-163909; therapeutic potential in multiple indications Normal-phase high-performance liquid chromatographic separations using ethoxynonafluorobutane as hexane alternative. I. Analytical and chiral applications Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model
is cites work of	wds:Q36401400-425F852A-2BA9-44C0-8D03-525E4486809C wds:Q34962263-9D7BEE47-EC1E-4545-A31F-BC8C93D516C0 wds:Q36709588-2CCA74D7-CD26-4A16-90DB-074893987241 wds:Q28592957-78ED3174-82CC-4D04-8279-323272E23CA0 wds:Q37125668-36B716D1-F13E-4870-B7F8-4B07405BBB82 wds:Q34575450-9197061F-2698-4BF6-8CEE-17CE4C42EEA4 wds:Q43640950-01CE0C1F-2F3A-42D3-AAE6-BE6CE146A7B8 wds:Q34070914-6AE8F158-68B2-4AFD-9273-5A2C90F66561

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 180 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software