About: Prolonged Jun N-terminal kinase (JNK) activation and the upregulation of p53 and p21(WAF1/CIP1) preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin

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About: Prolonged Jun N-terminal kinase (JNK) activation and the upregulation of p53 and p21(WAF1/CIP1) preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin Goto Sponge NotDistinct Permalink

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scientific article published on 01 July 2001

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в липні 2001 (uk) im Juli 2001 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xunetu de 2001 (ast) scientific article published on 01 July 2001 (en)
publication date	wds:Q74284498-94E6110C-CEBF-4849-8448-E2F597AEA796
publication date	2001-07-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q74284498-74597B8B-108C-445A-A25E-9A23D49E6414
language of work or name	English
cites work	wds:Q74284498-064610C1-ED41-4F08-9600-DD279B5EE34F wds:Q74284498-09773251-3BE4-49A5-9686-3A35330F515F wds:Q74284498-0D37D051-4AA2-4608-AE3A-529665A10893 wds:Q74284498-13991363-9DB0-4612-8290-E3B2B65DE6C9 wds:Q74284498-1CD71118-F32F-4E76-958A-D3397B2DB1AD wds:Q74284498-27B3A0A8-7A96-4E03-B212-13AFD5E22B87 wds:Q74284498-27E36D9F-0737-4D6E-BA1A-3D1B05EAACB8 wds:Q74284498-326FFED2-2FE3-471E-A826-3E7832A32343 wds:Q74284498-369C0975-655D-4D8A-90E2-70FD512BE8A9 wds:Q74284498-3F875BCE-5BE3-4034-86FB-4237508AB5F7 wds:Q74284498-4CED9F8A-3910-4A8C-8BB3-0C2A452C7CD6 wds:Q74284498-51882D4D-A836-4128-8B41-7A6DCC701852 wds:Q74284498-5277E3D7-CF13-47BD-9CB4-EDC505FB35D4 wds:Q74284498-5D2CE418-8999-474A-A3A9-C3993726B22A wds:Q74284498-5E9B9CA3-6D42-41EC-8CB4-D671F5B12174 wds:Q74284498-7295A221-DA43-49C4-BAD3-779F70524D59 wds:Q74284498-7B99347F-66FB-4A5B-BD14-6A6F418D4483 wds:Q74284498-7EF03A8E-1F91-4DA7-A2D4-63DC97FAD43E wds:Q74284498-802D350B-50A2-4D4A-B5CB-839E1583B239 wds:Q74284498-848020AA-1065-4266-8BD5-81B69D98A3CC wds:Q74284498-87D7BE2B-DC0E-4599-B33D-ADCF560BEA8E wds:Q74284498-87FEF552-83F8-4004-979A-4AC6D42E05DC wds:Q74284498-8BDE9AEE-F6A4-44EF-9428-D01380BEE959 wds:Q74284498-958A4B50-4C0E-4334-BF09-ED42A1148C80 wds:Q74284498-97948202-BC2F-4739-9868-5AF726AAD6CA wds:Q74284498-99559E2A-BDA3-4CDC-A2E0-6CC500FFC4EA wds:Q74284498-AB9BDDA3-B7B3-4DBC-85FE-3489C2CCE5F6 wds:Q74284498-B5420825-CE48-4C76-A727-D1273F7D3386 wds:Q74284498-B813F5FA-F153-4DE0-A3D9-2AC3735A36C8 wds:Q74284498-BF0838D9-F018-405D-B088-06E7AC75140E wds:Q74284498-C84822B6-A1BB-4436-B332-CE43A5F09C1B wds:Q74284498-D30ACC13-671C-48F7-B914-00A2765ACEF4 wds:Q74284498-D592DA74-70DF-471B-928C-376F7F3F3632 wds:Q74284498-DEBCC59C-F60F-4AC9-A86D-469D66D392EB wds:Q74284498-E61B0D1B-DB98-487C-B336-673D8252CABB wds:Q74284498-E9A98B1E-E3D7-419F-BE0C-F308CA100373 wds:Q74284498-F21E3CF7-AF7B-4AEA-8B2E-17736F5EC1AE wds:Q74284498-F56673C2-C1A3-4BC6-820E-8322D17E05AD wds:Q74284498-F878AA5E-4D9C-43C4-B123-628BF07D9759 wds:Q74284498-FB580C09-F356-4FA4-AA2E-B9511578B227
cites work	Liver regeneration 4: transcriptional control of liver regeneration. Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53 Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK Activation of Jun kinase is an early event in hepatic regeneration p53-dependent apoptosis modulates the cytotoxicity of anticancer agents The stress-activated protein kinase subfamily of c-Jun kinases The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation c-Jun is essential for normal mouse development and hepatogenesis Genetic determinants of p53-induced apoptosis and growth arrest Apoptosis by death factor Regulation of p53 in response to DNA damage p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1. Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1 Transcription factor AP-1 activity is required for initiation of DNA synthesis and is lost during cellular aging Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation Apoptosis. Its significance in cancer and cancer therapy Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death Liver regeneration. 2. Role of growth factors and cytokines in hepatic regeneration MEKK1/JNK signaling stabilizes and activates p53. Cell cycle control and cancer Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21 Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin Intrastriatal dopamine injection induces apoptosis through oxidation-involved activation of transcription factors AP-1 and NF-kappaB in rats. Tumor necrosis factor primes hepatocytes for DNA replication in the rat Retinoic acid repressed the expression of c-fos and c-jun and induced apoptosis in regenerating rat liver after partial hepatectomy Comparison of in vitro cell cytotoxic assays for tumor necrosis factor Protective role of p21(Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. Ceramide activates the stress-activated protein kinases Quercetin inhibited DNA synthesis and induced apoptosis associated with increase in c-fos mRNA level and the upregulation of p21WAF1CIP1 mRNA and protein expression during liver regeneration after partial hepatectomy Apoptosis induction by inhibitors of Ser/Thr phosphatases 1 and 2A is associated with transglutaminase activation in two different human epithelial tumour lines
author name string	wds:Q74284498-37CAA983-0663-4B87-BA84-D0EF5749CB38 wds:Q74284498-F30B3F95-349C-4D16-9C20-2C1EEE3AF760
author name string	K Kobayashi I Tsukamoto
rdfs:label	Prolonged Jun N-terminal kinase (JNK) activation and the upregulation of p53 and p21(WAF1/CIP1) preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin (en) Prolonged Jun N-terminal kinase (nl)
skos:prefLabel	Prolonged Jun N-terminal kinase (JNK) activation and the upregulation of p53 and p21(WAF1/CIP1) preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin (en) Prolonged Jun N-terminal kinase (nl)
name	Prolonged Jun N-terminal kinase (JNK) activation and the upregulation of p53 and p21(WAF1/CIP1) preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin (en) Prolonged Jun N-terminal kinase (nl)

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