About: Induction of antibody and T-cell responses by immunization with ISCOMS containing the 38-kilodalton protein of Mycobacterium tuberculosis

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About: Induction of antibody and T-cell responses by immunization with ISCOMS containing the 38-kilodalton protein of Mycobacterium tuberculosis Goto Sponge NotDistinct Permalink

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scientific article published on 01 August 2000

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 2000 (uk) im August 2000 veröffentlichter wissenschaftlicher Artikel (de) article scientifique publié en août 2000 (fr) artículu científicu espublizáu n'agostu de 2000 (ast) scientific article published on 01 August 2000 (en)
publication date	wds:Q74106326-CB9A83E7-2657-40F7-A8BC-333CA48753FB
publication date	2000-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q74106326-1FCEC37D-76E8-4DA1-ABBF-E11E7A9A5936
language of work or name	English
cites work	wds:Q74106326-0A512FB1-64CA-47B3-9C4C-3A4C9F73F9FD wds:Q74106326-11CC26C2-1399-48C4-9899-5DF1DBC324AA wds:Q74106326-18B399C7-2495-4115-AE2E-24FD24EB70B8 wds:Q74106326-20AD60D4-F48B-4B92-8BCF-89E52029C0EF wds:Q74106326-21CEF523-D51C-4014-B6C0-B5F30BE9E9BF wds:Q74106326-21DB2EEB-DE80-4A14-8639-6D683B4650BD wds:Q74106326-241B5534-4E9E-4E2F-AACE-7F5A2E0D6A69 wds:Q74106326-2B4B9AB4-4AD0-4B91-90C8-75B528B36E46 wds:Q74106326-2C8BC9E9-EB34-4841-8DA2-1F76ED0B8745 wds:Q74106326-32909096-D0D5-4696-9A26-DD916473D947 wds:Q74106326-3E9D25D2-E6E4-4D1E-AC96-EA60ECCFF3B5 wds:Q74106326-3F703BE4-7650-4EE8-9BF9-0327008DDEB7 wds:Q74106326-42215BCD-F75F-47B1-A92D-6E796D6A3377 wds:Q74106326-44573F68-8F28-4CF9-8B4A-568CE2D1DF82 wds:Q74106326-4558142C-23F3-4932-B5E8-A8FCB6A1A0C6 wds:Q74106326-4DA00EA2-865C-49C7-A4A7-C474391F9740 wds:Q74106326-505FA8F7-7B0F-4589-B0E3-D0868BD53AD0 wds:Q74106326-60EBAD14-3E55-4993-BCD4-5683D3674036 wds:Q74106326-6A9651A6-388B-49C2-97C4-2A8268AFD0B7 wds:Q74106326-7016A981-F1A1-49AE-9901-FD0EC47AB6E3 wds:Q74106326-7AC178BD-DE4E-4D5C-8783-0AA668D57D1B wds:Q74106326-910E6870-3047-4D43-9854-ADA366EF83C9 wds:Q74106326-91A92570-92B5-438B-ADE0-C31544B35681 wds:Q74106326-9276C32F-1EC2-4602-80A6-87CAC5B9433E wds:Q74106326-965A8434-7584-457B-BF7D-A37FAA1B63C2 wds:Q74106326-9FE8E121-E658-426E-AE48-A40B3535CA23 wds:Q74106326-ADEA6A55-66BC-4F4B-9DB8-D358C61C7399 wds:Q74106326-B5667BCD-65F5-4AD2-B175-796B1878D452 wds:Q74106326-BAD1D435-5B78-48CF-B8FB-51B68620DDD6 wds:Q74106326-CED66285-F25C-4054-8145-886742019AD3 wds:Q74106326-CF7CD593-E63A-4410-A446-2B305A4586B0 wds:Q74106326-D26B0955-C287-4C39-AA6B-4ED8F18870AA wds:Q74106326-D655C968-3D24-43B5-B377-DA2C10A140B6 wds:Q74106326-D76F92DB-72FE-4344-BED8-F7FCEF0529B2 wds:Q74106326-E10BFEB6-DA3C-4D81-B7A6-0BE7072FB0FB wds:Q74106326-E320563D-7D04-4159-8478-C8BA5FC76A26 wds:Q74106326-E9D69CC6-C03F-4564-B669-283E08C84DFE wds:Q74106326-EAFC28FC-F417-49AC-9FA8-7993B65AC6EE wds:Q74106326-F27EEFFA-BFED-44A3-8E49-EE72FE436B8E
cites work	Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection Disseminated tuberculosis in interferon gamma gene-disrupted mice Lipoprotein antigens of Mycobacterium tuberculosis A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids Adjuvant activity of non-toxic Quillaja saponaria Molina components for use in ISCOM matrix Immunological activity of a 38-kilodalton protein purified from Mycobacterium tuberculosis Clinical value of the measurement of Mycobacterium tuberculosis specific antibody in pulmonary tuberculosis A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding ISCOMs vaccine against experimental leishmaniasis. Studies on the detrimental effects of bivalent binding in a microtitration plate ELISA and possible remedies Synthetic delivery system for tuberculosis vaccines: immunological evaluation of the M. tuberculosis 38 kDa protein entrapped in biodegradable PLG microparticles T cell repertoire in tuberculosis: selective anergy to an immunodominant epitope of the 38-kDa antigen in patients with active disease ISCOMS — a novel strategy for mucosal immunization? Subunit vaccines against enveloped viruses: virosomes, micelles and other protein complexes The Mycobacterium tuberculosis 38-kDa antigen: overproduction in Escherichia coli, purification and characterization In vivo primary induction of virus-specific CTL by immunization with 9-mer synthetic peptides Influenza virus ISCOMs: antibody response in animals Increased immunogenicity of a non-amphipathic protein (BSA) after inclusion into iscoms Cellular immune responses in the murine lung to local immunization with influenza A virus glycoproteins in micelles and immunostimulatory complexes (iscoms). Quaternary structure of the immunostimulating complex (iscom). Effects of carbohydrate modification of Quillaja saponaria Molina QH-B fraction on adjuvant activity, cholesterol-binding capacity and toxicity ISCOMs and immunostimulation with viral antigens Initiation of cytotoxic T-cell response and protection of Balb/c mice by vaccination with an experimental ISCOMs respiratory syncytial virus subunit vaccine The iscom structure as an immune-enhancing moiety: experience with viral systems Involvement of interleukin-2 and interferon-gamma in the immune response induced by influenza virus iscoms Effect of iscoms and their adjuvant moiety (matrix) on the initial proliferation and IL-2 responses: comparison of spleen cells from mice inoculated with iscoms and/or matrix. Iscoms Containing PurifiedQuillajaSaponins Upregulate both Th1-like and Th2-like Immune Responses The nature of the immunogen determines the specificity of antibodies and T cells to selected peptides of the 38 kDa mycobacterial antigen Priming in vivo and quantification in vitro of class I MHC-restricted cytotoxic T cells to human papilloma virus type 11 early proteins (E6 and E7) using immunostimulating complexes (ISCOMs). Identification of new cytotoxic T-cell epitopes on the 38-kilodalton lipoglycoprotein of Mycobacterium tuberculosis by using lipopeptides Cytotoxic T cell responses to intracellular pathogens Internalization of iscom-borne antigens and presentation under MHC class I or class II restriction Influence of Quillaja saponaria triterpenoid content on the immunomodulatory capacity of Epstein-Barr virus iscoms Adjuvant activity of iscoms; effect of ratio and co-incorporation of antigen and adjuvant Antigen presentation by naive macrophages, dendritic cells and B cells to primed T lymphocytes and their cytokine production following exposure to immunostimulating complexes Induction of CD8+ CTL recognizing mycobacterial peptides 38 000 MW antigen-specific major histocompatibility complex class I restricted interferon-gamma-secreting CD8+ T cells in healthy contacts of tuberculosis.
author name string	wds:Q74106326-10610337-1164-4EEB-A704-9335BCED35EA wds:Q74106326-5CD3A2EA-A9AD-4012-8ED1-1A51959E25E2 wds:Q74106326-7BC5F48A-0F06-4EC8-8B4F-0F8B59B9FD96 wds:Q74106326-A59AE1D2-E040-445F-9A77-A99063495787 wds:Q74106326-EE0C2A49-D9DB-4A01-8A25-0A2A0D6BC49E
author name string	M Singh H Snippe A F Verheul D P da Fonseca J Frerichs
rdfs:label	Induction of antibody and T-cell responses by immunization with ISCOMS containing the 38-kilodalton protein of Mycobacterium tuberculosis (en)

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