About: Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile

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About: Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile Goto Sponge NotDistinct Permalink

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scientific article published on 01 March 2000

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) wüsseschaftlicher Artikel, wo im März 2000 veröffentlicht worden isch (gsw) im März 2000 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована в березні 2000 (uk) artículu científicu espublizáu en marzu de 2000 (ast) scientific article published on 01 March 2000 (en)
publication date	wds:Q73520544-8D2B1AD8-8158-495C-9231-B3DEA1376873
publication date	2000-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73520544-8C2A10E3-AEA0-4096-BA82-50EBDDFCB0A0
language of work or name	English
cites work	wds:Q73520544-FAEE165C-66F2-4F09-98FB-BC3FB474A57D
cites work	Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies
author name string	wds:Q73520544-1A09EDC6-269E-44B7-8C25-EACA8CA42952 wds:Q73520544-2B980FFF-849A-4DEB-9725-50BEF4EBD059 wds:Q73520544-3EAC9181-984F-4340-AD6F-F7C4F7566129 wds:Q73520544-4BA4C317-7E25-4A10-83DB-03D4BAEA831F wds:Q73520544-5F892508-A66C-41C8-8CAE-5436A01C2845 wds:Q73520544-CE33BF53-6B0A-463E-942C-314ED1E1B59D
author name string	W E Paul A Sher P Caspar D Jankovic M C Kullberg N Noben-Trauth
rdfs:label	Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile (en) Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile (nl)
skos:prefLabel	Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile (en) Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile (nl)
name	Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile (en) Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile (nl)
title	wds:Q73520544-48D1AB56-522C-4823-9D59-50724C453880
title	Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile (en)
page(s)	wds:Q73520544-30B54CB1-3E0A-414E-9CF4-AA70BF7AE9E3
page(s)	3047-3055
instance of	wds:Q73520544-D741B2AA-F7DC-4150-99D6-5A5A36A7C985
instance of	scholarly article
PubMed ID	wds:Q73520544-4B04F614-1275-46D7-924A-00AB7E7E4419
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10706693
PubMed ID	10706693
published in	wds:Q73520544-697B65B2-46F8-45EA-ACD6-AD0CBCB8B3DC
published in	Journal of Immunology
issue	wds:Q73520544-20657DF2-4E11-49EC-BDDD-B47D766712E1
volume	wds:Q73520544-C18597B8-DB60-4F80-987B-E6F3826D6C3A
issue	6
volume	164
DOI	wds:Q73520544-958AF730-56B0-44F9-BD25-615708F8F223
DOI	http://dx.doi.org/10.4049/JIMMUNOL.164.6.3047
DOI	10.4049/JIMMUNOL.164.6.3047
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73520544
is cites work of	IL-12 up-regulates T-bet independently of IFN-gamma in human CD4+ T cells Regulation of CD4+ T-cell polarization by suppressor of cytokine signalling proteins CD4 T cells: fates, functions, and faults T cell differentiation: a mechanistic view STAT6-mediated suppression of erythropoiesis in an experimental model of malarial anemia Differentiation of effector CD4 T cell populations (*) Functional diversity and plasticity of human dendritic cell subsets The differential expression of IL-4 and IL-13 and its impact on type-2 immunity IL-33-activated dendritic cells induce an atypical TH2-type response Asthma-related environmental fungus, Alternaria, activates dendritic cells and produces potent Th2 adjuvant activity Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: cytokine requirements for the induction and maintenance of intestinal inflammation IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. Dendritic cell regulation of TH1-TH2 development Dendritic cell-mediated T cell polarization Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway The different faces of Notch in T-helper-cell differentiation Pinpointing IL-4-independent acquisition and IL-4-influenced maintenance of Th2 activity by CD4 T cells. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function The immunobiology of schistosomiasis Cytokine memory of T helper lymphocytes Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. An instructive component in T helper cell type 2 (Th2) development mediated by GATA-3. Normalization of obesity-associated insulin resistance through immunotherapy Transcriptional regulation by STAT6. IL-13 gene-deficient mice are susceptible to cutaneous L. mexicana infection The Relative Contribution of IL-4 Receptor Signaling and IL-10 to Susceptibility toLeishmania major Lewis X oligosaccharides targeting to DC-SIGN enhanced antigen-specific immune response Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. The lineage decisions of helper T cells Transcription: tantalizing times for T cells T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. The Differentiation of CD4(+) T-Helper Cell Subsets in the Context of Helminth Parasite Infection Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting Insights into the initiation of type 2 immune responses Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. Th2 cells: orchestrating barrier immunity How are T(H)2-type immune responses initiated and amplified? How diverse--CD4 effector T cells and their functions Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection. The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses

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