About: Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells

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About: Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells Goto Sponge NotDistinct Permalink

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scientific article published on 01 July 1997

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в липні 1997 (uk) im Juli 1997 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xunetu de 1997 (ast) scientific article published on 01 July 1997 (en)
publication date	wds:Q73513756-C28EC297-56B9-4182-B022-FDDA70514BD9
publication date	1997-07-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q73513756-6FFFC518-4954-4D11-9F4F-8F00A418D997 wds:Q73513756-F83190EF-0495-4AD7-9872-7529EE28C41D
cites work	Saintopin, a new antitumor antibiotic with topoisomerase II dependent DNA cleavage activity, from Paecilomyces UCT-4B, a new antitumor antibiotic with topoisomerase II mediated DNA cleavage activity, from streptomyces sp.
author name string	wds:Q73513756-00D31647-887D-48C1-9DAB-99BF70535C7C wds:Q73513756-14671006-567D-472D-8CFA-A8A38475DAAC wds:Q73513756-293917FF-F571-4CE7-8B89-16AB9A9330AB wds:Q73513756-3966DB1F-2B3D-47D6-B3C8-8FC1329FBAAC wds:Q73513756-768343F5-5FC9-46AD-BB01-C95BF8560B1C wds:Q73513756-7B1DB760-CA8B-4719-8316-9E75ACD6F04C wds:Q73513756-982AC17E-5066-436E-8FB9-E8325EEBB661
author name string	Y Pommier K W Kohn G Kohlhagen M Valenti M E Wall M C Wani W Nieves-Neira
rdfs:label	Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells (en) Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells (nl)
skos:prefLabel	Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells (en) Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells (nl)
name	Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells (en) Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells (nl)
title	wds:Q73513756-17694781-B0D4-4D27-801A-85DA9148CE3D
title	Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells (en)
page(s)	wds:Q73513756-A0E0D1E0-825C-48F2-87E1-9F7DE0916F0A
page(s)	82-87
instance of	wds:Q73513756-3A55A3F1-647F-4E1B-B771-FF3B82A8031A
instance of	scholarly article
main subject	wds:Q73513756-37492593-5124-4DF2-858F-76C50340E1F4 wds:Q73513756-A2FEC140-0DCF-40B8-BD80-EDEA1A965D4D
main subject	cytotoxicity colon carcinoma
PubMed ID	wds:Q73513756-FCBFA8EF-6163-4F36-A154-798781E5E461
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9224816
PubMed ID	9224816
published in	wds:Q73513756-F07C8A6C-6364-4742-8587-70B228B97709
published in	Molecular Pharmacology
issue	wds:Q73513756-86CFD467-D9EE-414A-85DB-AEE6AEA7370D
volume	wds:Q73513756-5A37B05C-03AA-41A3-B536-EB097EF4AC5E
issue	1
volume	52
DOI	wds:Q73513756-1415C25F-8336-421F-ACE3-95C8D3B91D5A
DOI	http://dx.doi.org/10.1124/MOL.52.1.82
DOI	10.1124/MOL.52.1.82
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73513756
is cites work of	Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct 1,N6-ethenoadenine Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells Poisoning of human DNA topoisomerase I by ecteinascidin 743, an anticancer drug that selectively alkylates DNA in the minor groove Diversity of DNA topoisomerases I and inhibitors. DNA sequence selectivity of human topoisomerase I-mediated DNA cleavage induced by camptothecin Elevations of DNA topoisomerase I in transitional cell carcinoma of the urinary bladder: correlation with DNA topoisomerase II-alpha and p53 expression Enhancement of camptothecin-induced topoisomerase I cleavage complexes by the acetaldehyde adduct N2-ethyl-2'-deoxyguanosine Pre-clinical evaluation of SN-38 and novel camptothecin analogs against human chronic B-cell lymphocytic leukemia lymphocytes Topoisomerase I inhibitors and drug resistance
is cites work of	wds:Q42623345-8E452F35-2078-4ECA-9C3B-E62E5967D1C3 wds:Q77333600-5DDCADA7-09AF-4847-862A-9C629B13FC9F wds:Q73215656-641BA3F3-6F9E-4EDA-BE47-89958BCBB4FD wds:Q28343739-14F35A52-8FE7-4EC0-8476-FE55A66E5785 wds:Q38332699-DFDB62FE-CEC4-4CF4-876F-2AB17F991885 wds:Q48005418-DA94DAB7-52E0-4190-A88B-D83664A86BD4 wds:Q40028536-95AFDDF6-E3F4-4CA2-9B9E-F7830E57D351 wds:Q77340375-9768B44F-9A9A-4D52-A17A-16A1C1DF9634 wds:Q36390575-668E67FE-8EF7-4567-802D-EADB47808CCB wds:Q37592361-C14BD36E-8399-4E0A-A0F4-4F68F98056C8

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