About: Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer

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About: Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer Goto Sponge NotDistinct Permalink

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scientific article published on 01 February 2000

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в лютому 2000 (uk) im Februar 2000 veröffentlichter wissenschaftlicher Artikel (de) wüsseschaftlicher Artikel, wo im Hornig 2000 veröffentlicht worden isch (gsw) article scientifique publié en 2000 (fr) artículu científicu espublizáu en febreru de 2000 (ast) artikull shkencor i botuar më 01 shkurt 2000 (sq) scientific article published on 01 February 2000 (en)
publication date	wds:Q73445688-39DE8B8E-8EE0-4736-94B3-458352783DCB
publication date	2000-02-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73445688-BA723F5B-BEBC-46E9-A2B8-2EF544260D55
language of work or name	English
author name string	wds:Q73445688-0737C68B-1EC5-439B-9F1F-C8DD7BAF1CC3 wds:Q73445688-0DA37D1F-A0BB-451E-9D96-BB63094826DA wds:Q73445688-156F21F1-1C1E-41AC-8F2A-42E0CED64D2D wds:Q73445688-1D6AB1E1-33D9-4BC1-BDA0-17E4D17EFB63 wds:Q73445688-1ED22C9A-290C-4829-8238-FA6E8D5D1DFD wds:Q73445688-26E7BBD6-92C2-4E99-91C5-E06AE90E305B wds:Q73445688-277B7320-2AC6-4716-8E24-77993C8A50DF wds:Q73445688-37ADD157-8FBE-4BC5-9A32-41A622200B98 wds:Q73445688-3DE9EFA4-CCF4-438E-BFC4-C25EBF396596 wds:Q73445688-414CAB98-C32B-4746-82A2-459087EA3944 wds:Q73445688-5A1A90DC-7FF1-4E3D-A557-00F9C1247876 wds:Q73445688-5BEFFBC2-FB12-45D2-A497-F808A3374D29 wds:Q73445688-5C8687D4-165D-4B73-9E57-F926CD1071BA wds:Q73445688-5E11E0E6-1FBB-4C60-BDF3-D37A7DD39F29 wds:Q73445688-8E60908D-8768-4A11-AD6F-F84E5C569CF7 wds:Q73445688-96FD1C20-B4E0-486D-80A2-08B50D8618D0 wds:Q73445688-AA33AD0A-F9B1-4F76-9B12-4B039D5F81CD wds:Q73445688-DB0AAF5F-D22B-4CBA-910F-CDFB15798B33 wds:Q73445688-EC2DB1FE-0705-4800-9962-F8C9EFD15E19 wds:Q73445688-F997D7A6-E56A-4753-8795-DC1BA95B55D4
author name string	C Chow C Bowden K H Cowan M Noone D R Kohler F T Hakim R E Gress I D Horak A Todd R B Nussenblatt J Chiao R Woestenborghs G Larkin J Zujewski W C Kopp C J Bol D W End R T Belly A B Kremer V K Piotrovsky
rdfs:label	Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer (en) Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer (nl) Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer (sq)
skos:prefLabel	Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer (en) Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer (nl) Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer (sq)
name	Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer (en) Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer (nl) Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer (sq)
title	wds:Q73445688-19D53431-0D73-453B-A2DF-5E96008997E0
title	Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer (en)
page(s)	wds:Q73445688-4D8DA3D9-B47B-4665-B110-72B585B92776
page(s)	927-941
instance of	wds:Q73445688-3C102622-F58D-4413-8BBE-1120478D7DE2
instance of	scholarly article
PubMed ID	wds:Q73445688-5D4AB86F-7DA0-4C73-A447-D79A83AC8060
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10673536
PubMed ID	10673536
published in	wds:Q73445688-AE23FFAD-BCC7-47CC-9820-5979D763160F
published in	Journal of Clinical Oncology
issue	wds:Q73445688-CFA0DBC1-2ABA-4820-9D64-8E9188C7354E
volume	wds:Q73445688-7CCD947F-1E74-443A-B8E0-89E0C0077CC0
issue	4
volume	18
DOI	wds:Q73445688-C62E4418-09AC-416D-BF8C-78D21F5BE12A
DOI	http://dx.doi.org/10.1200/JCO.2000.18.4.927
DOI	10.1200/JCO.2000.18.4.927
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73445688
is cites work of	Trimodality treatment in Stage III nonsmall cell lung carcinoma: prrognostic impact of K-ras mutations after neoadjuvant therapy JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis Farnesyl protein transferase inhibitors as targeted therapies for hematologic malignancies Development of farsenyl transferase inhibitors as anticancer agents Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention. Advances in Molecular Therapies in Patients with Brain Tumors Targeting protein prenylation for cancer therapy Phase I trial of a combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in advanced malignancies Novel therapies for lung cancer Dosing strategies for anticancer drugs: the good, the bad and body-surface area Rational modification of a candidate cancer drug for use against Chagas disease Pharmacological Characterization, Structural Studies, and In Vivo Activities of Anti-Chagas Disease Lead Compounds Derived from Tipifarnib Tamoxifen and the farnesyl transferase inhibitor FTI-277 synergize to inhibit growth in estrogen receptor-positive breast tumor cell lines Phase I and pharmacokinetic study of irinotecan in combination with R115777, a farnesyl protein transferase inhibitor Phase I and pharmacological study of the farnesyltransferase inhibitor tipifarnib (Zarnestra, R115777) in combination with gemcitabine and cisplatin in patients with advanced solid tumours A phase II trial of R115777, an oral farnesyl transferase inhibitor, in patients with advanced urothelial tract transitional cell carcinoma Phase I and pharmacological study of the oral farnesyltransferase inhibitor SCH 66336 given once daily to patients with advanced solid tumours Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas. Clinical impact of novel treatment strategies

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