About: Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

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About: Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase Goto Sponge NotDistinct Permalink

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scientific article published on 01 December 1999

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 1999 (uk) article scientifique publié en 1999 (fr) im Dezember 1999 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 1999 (ast) scientific article published on 01 December 1999 (en)
publication date	wds:Q73316561-FCD00D85-A7B7-4D0C-958E-C1987907776C
publication date	1999-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73316561-ED5B7130-4C4C-48D0-81FC-CF7B767A5D95
language of work or name	English
author name string	wds:Q73316561-1A5DD004-26EE-4C8D-A768-3C47ABB267C0 wds:Q73316561-28698D89-654C-40C7-A854-EC5C6581A28B wds:Q73316561-2957EC25-FD15-44AA-9E64-0EFB6810C636 wds:Q73316561-35F52133-BE30-4BDB-90E1-CBBD1204ADD5 wds:Q73316561-564B2B53-CF08-438A-8EFF-9F6EEEA24ACE wds:Q73316561-9E779A24-25ED-4D32-972A-7FB763942A36 wds:Q73316561-BA7BE431-C7B7-4409-BB64-536FB8EB0B4A wds:Q73316561-C75D9B0E-6EB7-4BDC-8DD6-268184844E2F wds:Q73316561-DBC29E55-518F-4A64-9C84-A62DB11BD4D3
author name string	Y Zhuang A G Estévez J S Beckman L Barbeito C Reiter J P Crow M M Tarpey J B Sampson G J Richardson
rdfs:label	Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase (en) Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase (nl)
skos:prefLabel	Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase (en) Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase (nl)
name	Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase (en) Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase (nl)
title	wds:Q73316561-B7FB499B-EFD2-46FA-BE92-24AF9132D7A8
title	Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase (en)
page(s)	wds:Q73316561-D69925AE-FAC4-41BC-8112-2FD8EF4516B7
page(s)	2498-2500
instance of	wds:Q73316561-91DE1A6B-9AA6-4B24-A37F-188764347963
instance of	scholarly article
main subject	wds:Q73316561-5D16FA53-4A40-45C4-B5C6-50131E7FCB02
main subject	apoptotic process
PubMed ID	wds:Q73316561-601117F9-DF4A-4720-B273-32CC8B9221D8
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10617463
PubMed ID	10617463
published in	wds:Q73316561-818740BC-2772-4D09-8238-9C0379C2C929
published in	Science
issue	wds:Q73316561-80573F18-515D-4AE5-BE7D-5C600ED84B22
volume	wds:Q73316561-D0A94E7E-0173-45B6-9660-3209873B6FCD
issue	5449
volume	286
DOI	wds:Q73316561-5560D3BD-B9AA-467A-BAF2-B81B40904B9E
DOI	http://dx.doi.org/10.1126/SCIENCE.286.5449.2498
DOI	10.1126/SCIENCE.286.5449.2498
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73316561
is cites work of	Metals in our minds: therapeutic implications for neurodegenerative disorders Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS. GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis Mitochondrial pathobiology in ALS. Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities Proline suppresses apoptosis in the fungal pathogen Colletotrichum trifolii Cellular transport and homeostasis of essential and nonessential metals Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis. Neurodegenerative diseases and oxidative stress Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis Complex genetics of amyotrophic lateral sclerosis Expression of zinc-deficient human superoxide dismutase in Drosophila neurons produces a locomotor defect linked to mitochondrial dysfunction Mitochondrial dysfunction in neurodegenerative diseases associated with copper imbalance Understanding peroxynitrite biochemistry and its potential for treating human diseases Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups Metals and neuroscience. The regulatory role of nitric oxide in apoptosis Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment Genetically engineered mouse models of neurodegenerative diseases The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis Using theoretical protein isotopic distributions to parse small-mass-difference post-translational modifications via mass spectrometry Measuring copper and zinc superoxide dismutase from spinal cord tissue using electrospray mass spectrometry. Oxidative stress in neurodegeneration: cause or consequence? Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis. Molecular biology of amyotrophic lateral sclerosis: insights from genetics Twenty years of metallo-neurobiology: where to now? Recent advances in amyotrophic lateral sclerosis research Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS Nitric oxide and the regulation of gene expression Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: decreased stability of the apo state Mutant Cu,Zn superoxide dismutases and familial amyotrophic lateral sclerosis: evaluation of oxidative hypotheses Nitric oxide, oxidants, and protein tyrosine nitration Mapping superoxide dismutase 1 domains of non-native interaction: roles of intra- and intermolecular disulfide bonding in aggregation Oxygen-induced maturation of SOD1: a key role for disulfide formation by the copper chaperone CCS. Nitric oxide and peroxynitrite in health and disease Unraveling peroxynitrite formation in biological systems. Peroxynitrite formation from biochemical and cellular fluxes of nitric oxide and superoxide Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1

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