About: SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation

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About: SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation Goto Sponge NotDistinct Permalink

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scientific article published on 01 December 1999

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 1999 (uk) im Dezember 1999 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 1999 (ast) scientific article published on 01 December 1999 (en)
publication date	wds:Q73279955-79D7DBFE-76E1-422B-961C-380C041FC212
publication date	1999-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73279955-C22E8048-EBA5-44B0-A3AB-6DA0D828F45E
language of work or name	English
author name string	wds:Q73279955-3C7F5406-8DAE-4C6E-BE65-C90ABA18E906 wds:Q73279955-61F4C17F-9021-49FB-8E69-2BF3C9B777E8 wds:Q73279955-736655F4-8EF8-4F03-8E60-A25971FB52F9 wds:Q73279955-C0B92648-6623-46A4-9F43-CD12350CE26D
author name string	A L Cheung S J Projan Y Chien A C Manna
rdfs:label	SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation (en) SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation (nl)
skos:prefLabel	SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation (en) SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation (nl)
name	SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation (en) SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation (nl)
title	wds:Q73279955-6E675E28-4F23-4660-8E30-F36AD803FBBF
title	SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation (en)
page(s)	wds:Q73279955-D2C00A14-C782-4628-87DD-8AC03769540D
page(s)	37169-37176
instance of	wds:Q73279955-32277B7C-4095-4EB6-9E13-11199FE78761
instance of	scholarly article
main subject	wds:Q73279955-C7274155-2209-4BC3-9E9B-749256F57419
main subject	Staphylococcus aureus
PubMed ID	wds:Q73279955-378FF3FA-4307-446A-8AD2-59E7D797B6FC
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10601279
PubMed ID	10601279
published in	wds:Q73279955-FBD34727-58FE-4CEA-BDF7-AC74BD5E8AA3
published in	Journal of Biological Chemistry
issue	wds:Q73279955-DC521A29-CDD2-482E-B734-52EFB3ADB1CC
volume	wds:Q73279955-4A7AFBC7-2B0C-49D3-9441-1D0975FCD637
issue	52
volume	274
DOI	wds:Q73279955-27880378-95A3-436D-8DCE-35959DF5F29E
DOI	http://dx.doi.org/10.1074/JBC.274.52.37169
DOI	10.1074/JBC.274.52.37169
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73279955
is cites work of	Global regulation of Staphylococcus aureus genes by Rot A rot mutation restores parental virulence to an agr-null Staphylococcus aureus strain in a rabbit model of endocarditis Identification, cloning, and initial characterization of rot, a locus encoding a regulator of virulence factor expression in Staphylococcus aureus SarT, a repressor of alpha-hemolysin in Staphylococcus aureus sarU, a sarA homolog, is repressed by SarT and regulates virulence genes in Staphylococcus aureus sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4. Defining the strain-dependent impact of the Staphylococcal accessory regulator (sarA) on the alpha-toxin phenotype of Staphylococcus aureus SarA based novel therapeutic candidate against Staphylococcus aureus associated with vascular graft infections Bacterial endophthalmitis in the age of outpatient intravitreal therapies and cataract surgeries: host-microbe interactions in intraocular infection Regulation of bacterial protease activity. Characterizing the effect of the Staphylococcus aureus virulence factor regulator, SarA, on log-phase mRNA half-lives Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus Comparative genomics of Staphylococcus aureus musculoskeletal isolates. Characterization of Staphylococcus aureus SarA binding sites Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus Identification of sarV (SA2062), a new transcriptional regulator, is repressed by SarA and MgrA (SA0641) and involved in the regulation of autolysis in Staphylococcus aureus Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci. Characterization of sarR, a modulator of sar expression in Staphylococcus aureus SarS, a SarA homolog repressible by agr, is an activator of protein A synthesis in Staphylococcus aureus Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus In the Staphylococcus aureus two-component system sae, the response regulator SaeR binds to a direct repeat sequence and DNA binding requires phosphorylation by the sensor kinase SaeS SarA is an essential positive regulator of Staphylococcus epidermidis biofilm development. Daptomycin resistance mechanisms in clinically derived Staphylococcus aureus strains assessed by a combined transcriptomics and proteomics approach MsrR, a putative cell envelope-associated element involved in Staphylococcus aureus sarA attenuation Regulation of transcription by eukaryotic-like serine-threonine kinases and phosphatases in Gram-positive bacterial pathogens Regulation of prokaryotic gene expression by eukaryotic-like enzymes Regulation of Staphylococcus aureus capsular polysaccharide expression by agr and sarA. The SaeRS Two-Component System Controls Survival of Staphylococcus aureus in Human Blood through Regulation of Coagulase Staphylococcus aureus agr and sarA functions are required for invasive infection but not inflammatory responses in the lung Virulence characteristic and MLST-agr genetic background of high-level mupirocin-resistant, MRSA isolates from Shanghai and Wenzhou, China Control of thioredoxin reductase gene (trxB) transcription by SarA in Staphylococcus aureus Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus SarA of Staphylococcus aureus binds to the sarA promoter to regulate gene expression Expression of the sarA family of genes in different strains of Staphylococcus aureus Expression of SarX, a negative regulator of agr and exoprotein synthesis, is activated by MgrA in Staphylococcus aureus sarZ, a sarA family gene, is transcriptionally activated by MgrA and is involved in the regulation of genes encoding exoproteins in Staphylococcus aureus Transcriptional regulation of the agr locus and the identification of DNA binding residues of the global regulatory protein SarR in Staphylococcus aureus Rot repression of enterotoxin B expression in Staphylococcus aureus SarA is a repressor of hla (alpha-hemolysin) transcription in Staphylococcus aureus: its apparent role as an activator of hla in the prototype strain NCTC 8325 depends on reduced expression of sarS. Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance At the crossroads of bacterial metabolism and virulence factor synthesis in Staphylococci SaeR binds a consensus sequence within virulence gene promoters to advance USA300 pathogenesis The Staphylococcal Biofilm: Adhesins, Regulation, and Host Response sarA-mediated repression of protease production plays a key role in the pathogenesis of Staphylococcus aureus USA300 isolates. Mapping the transcription start points of the Staphylococcus aureus eap, emp, and vwb promoters reveals a conserved octanucleotide sequence that is essential for expression of these genes SarA positively controls bap-dependent biofilm formation in Staphylococcus aureus Reduced vancomycin susceptibility in Staphylococcus aureus, including vancomycin-intermediate and heterogeneous vancomycin-intermediate strains: resistance mechanisms, laboratory detection, and clinical implications SarT influences sarS expression in Staphylococcus aureus SarZ promotes the expression of virulence factors and represses biofilm formation by modulating SarA and agr in Staphylococcus aureus Peptide signaling in the staphylococci CodY-mediated regulation of the Staphylococcus aureus Agr system integrates nutritional and population density signals Global virulence regulation in Staphylococcus aureus: pinpointing the roles of ClpP and ClpX in the sar/agr regulatory network The CshA DEAD-box RNA helicase is important for quorum sensing control in Staphylococcus aureus Regulation of the mazEF toxin-antitoxin module in Staphylococcus aureus and its impact on sigB expression

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