About: IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites

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About: IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites Goto Sponge NotDistinct Permalink

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scientific article published on 01 December 2000

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 2000 (uk) مقالة علمية تنشرت ف 1 دجنبر 2000 (ary) im Dezember 2000 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 2000 (ast) scientific article published on 01 December 2000 (en)
publication date	wds:Q73209269-99534B9F-7245-465D-BCA4-92E47C5CECFA
publication date	2000-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73209269-F5654523-C0E7-428D-BB41-E41E861DDB8D
language of work or name	English
cites work	wds:Q73209269-3B898106-F3F2-4D52-9484-2038BF7B9CA6
cites work	Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
author name string	wds:Q73209269-1BEE37E2-4186-4642-9A56-DE25219C24CF wds:Q73209269-47303878-9ACE-4C6E-AFFF-BDFC7A3F25B5 wds:Q73209269-594E3B6E-972F-4814-92E4-AE1A9CE778B7 wds:Q73209269-A667085D-CABC-4613-9B8A-7C96EFB5308B wds:Q73209269-CAF140D4-B210-47F6-A4D9-E53F25D466DE wds:Q73209269-DE22DF9B-1418-43C9-B1CF-7DDDCCB35CD0
author name string	X Wang C Wu J J O'Shea J Magram D H Presky M Gadina
rdfs:label	IL-12 receptor beta 2 (nl) IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites (en)
skos:prefLabel	IL-12 receptor beta 2 (nl) IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites (en)
name	IL-12 receptor beta 2 (nl) IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites (en)
title	wds:Q73209269-A50F9AA7-4B2E-40F3-B009-AA88F4B2EBF8
title	IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites (en)
page(s)	wds:Q73209269-14705C1E-370B-4CA8-B742-D68D5BDC4235
page(s)	6221-6228
instance of	wds:Q73209269-00C08D45-89E3-4225-9F93-A8EF861F3968
instance of	scholarly article
PubMed ID	wds:Q73209269-A12A4786-0B56-4DBD-8815-8F039E2635FA
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11086056
PubMed ID	11086056
published in	wds:Q73209269-828B4FE2-9FC6-42A9-BEE3-3195BC2C772C
published in	Journal of Immunology
issue	wds:Q73209269-6BC3DAD1-F4C4-42B1-9F75-07113D2FD497
volume	wds:Q73209269-0A1AAB0A-62F2-44B8-BE75-1CE7293F96AD
issue	11
volume	165
DOI	wds:Q73209269-78E032FD-E5D4-4B55-9B4F-108FD692C0A6
DOI	http://dx.doi.org/10.4049/JIMMUNOL.165.11.6221
DOI	10.4049/JIMMUNOL.165.11.6221
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73209269
is cites work of	Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation A T-bet gradient controls the fate and function of CCR6-RORγt+ innate lymphoid cells The biology of IL-12: coordinating innate and adaptive immune responses Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rbeta1 isoform that enhances DC migration Human genetics of intracellular infectious diseases: molecular and cellular immunity against mycobacteria and salmonellae The composition and signaling of the IL-35 receptor are unconventional Novel IL-12 family members shed light on the orchestration of Th1 responses Gene transfer of CD154 and IL12 cDNA induces an anti-leukemic immunity in a murine model of acute leukemia. Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. CB(1) and CB(2) cannabinoid receptors mediate different aspects of delta-9-tetrahydrocannabinol (THC)-induced T helper cell shift following immune activation by Legionella pneumophila infection Endogenous IL-12 triggers an antiangiogenic program in melanoma cells. Respiratory tract infection with Mycoplasma pneumoniae in interleukin-12 knockout mice results in improved bacterial clearance and reduced pulmonary inflammation Intranasal interleukin-12 therapy inhibits Mycoplasma pneumoniae clearance and sustains airway obstruction in murine pneumonia The power of combinatorial immunology: IL-12 and IL-12-related dimeric cytokines in infectious diseases Control of human host immunity to mycobacteria. Natural killer cells and Helicobacter pylori infection: bacterial antigens and interleukin-12 act synergistically to induce gamma interferon production How diverse--CD4 effector T cells and their functions BOB.1/OBF.1 controls the balance of TH1 and TH2 immune responses T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription Interleukin-35: odd one out or part of the family? Accelerated thymocyte maturation in IL-12Rβ2-deficient mice contributes to increased susceptibility to autoimmune inflammatory demyelination Differential effects of stimulatory factors on natural killer cell activities of young and aged mice Interferon gamma stabilizes the T helper cell type 1 phenotype. Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice. Signaling by type I and II cytokine receptors: ten years after Role of cytokine p40 family in multiple sclerosis Inhibiting cytokines of the interleukin-12 family: recent advances and novel challenges. Systemic but not local infections elicit immunosuppressive IL-10 production by natural killer cells Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet Reduced expression of IL-12 receptor beta2 and IL-18 receptor alpha genes in natural killer cells and macrophages derived from B6-mi/mi mice A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations Proinflammatory cytokine signaling required for the generation of natural killer cell memory The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection Cytokine control of inflammation and repair in the pathology of multiple sclerosis. CD8 T cells in innate immune responses: using STAT4-dependent but antigen-independent pathways to gamma interferon during viral infection Cutting edge: a novel mechanism bridging innate and adaptive immunity: IL-12 induction of CD25 to form high-affinity IL-2 receptors on NK cells Barrier immunity and IL-17. Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates Role of IL-12 Receptor β1 in Regulation of T Cell Response by APC in Experimental Autoimmune Encephalomyelitis Interleukin (IL)-12 receptor beta1 or IL-12 receptor beta 2 deficiency in mice indicates that IL-12 and IL-23 are not essential for host recovery from viral encephalitis Expression of the bovine high affinity IL-12 receptor beta2 Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease IL-12R beta 2 promotes the development of CD4+CD25+ regulatory T cells Efficacy and safety of ustekinumab in adolescents. Synthetic Deletion of the Interleukin 23 Receptor (IL-23R) Stalk Region Led to Autonomous IL-23R Homodimerization and Activation Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases

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