About: Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific article published on 01 December 1999

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 1999 (uk) article scientifique publié en 1999 (fr) im Dezember 1999 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 1999 (ast) scientific article published on 01 December 1999 (en)
publication date	wds:Q73201596-22134E7F-3563-4A79-A9AD-7E0229ABB5C8
publication date	1999-12-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q73201596-00E7BF2D-C92C-44E9-B5BE-E28DD86073F6 wds:Q73201596-0BECEAAF-315B-48C7-AB5C-83ADDB6F1235 wds:Q73201596-355235F2-1FD8-43E7-884B-CE1FB8AA94FB wds:Q73201596-47774167-6C6C-4D8D-8B64-0AFAF5BCCEB1 wds:Q73201596-62084822-3008-488E-8E3F-4B40B40B30B9 wds:Q73201596-81C9A14F-12AF-4A82-8BDC-E0BC27A47406 wds:Q73201596-F920D194-EF59-48AB-A68E-68ED06663C71 wds:Q73201596-FB20A758-09CF-4032-848A-762C38AC0949 wds:Q73201596-FD0F5453-56B3-46B0-86D7-8BCA2289F7CB wds:Q73201596-FDDA9EBB-FC89-464D-96FE-1025FC431411
author name string	J Chen J A Javitch T P Sakmar L A Snyder J A Ballesteros D S Hartman M Suehiro M M Simpson V Chiappa T Godel
rdfs:label	Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments (en) Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments (nl)
skos:prefLabel	Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments (en) Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments (nl)
name	Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments (en) Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments (nl)
title	wds:Q73201596-66D32314-4DA9-4465-9A63-E67E5AE6E2D1
title	Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments (en)
page(s)	wds:Q73201596-AE70498D-ED6E-4D14-B33B-1299DB0691B1
page(s)	1116-1126
instance of	wds:Q73201596-01F7FE4F-70EA-48EB-B27B-20E263E173F5
instance of	scholarly article
PubMed ID	wds:Q73201596-3601591B-9EE1-4709-A048-DCFDF020B0C4
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10570038
PubMed ID	10570038
published in	wds:Q73201596-1C7C4AC5-1536-4407-86FF-E2F9FEB23D72
published in	Molecular Pharmacology
issue	wds:Q73201596-C43319D6-512A-40D6-BE02-7A607AA15482
volume	wds:Q73201596-578E3D03-BB06-4C43-91F8-2A6B4FA42528
issue	6
volume	56
DOI	wds:Q73201596-3AD89191-1AA2-4225-937A-7CA01DAFED0A
DOI	http://dx.doi.org/10.1124/MOL.56.6.1116
DOI	10.1124/MOL.56.6.1116
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73201596
is cites work of	Molecular basis of ligand dissociation in β-adrenergic receptors Subtype selectivity of dopamine receptor ligands: insights from structure and ligand-based methods The predicted 3D structure of the human D2 dopamine receptor and the binding site and binding affinities for agonists and antagonists. Use of the substituted cysteine accessibility method to study the structure and function of G protein-coupled receptors. Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors Molecular determinants of selectivity and efficacy at the dopamine D3 receptor. The dopamine D(4) receptor: one decade of research Ligand selectivity of D2 dopamine receptors is modulated by changes in local dynamics produced by sodium binding. Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist Mutagenic mapping suggests a novel binding mode for selective agonists of M1 muscarinic acetylcholine receptors Three-dimensional representations of G protein-coupled receptor structures and mechanisms G protein-coupled receptor drug discovery: implications from the crystal structure of rhodopsin. Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation. Dopamine receptors: from structure to behavior Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3. A critical role for a tyrosine residue in the cannabinoid receptors for ligand recognition Structure modeling of the chemokine receptor CCR5: implications for ligand binding and selectivity Transmembrane segment five serines of the D4 dopamine receptor uniquely influence the interactions of dopamine, norepinephrine, and Ro10-4548. A two-step target binding and selectivity support vector machines approach for virtual screening of dopamine receptor subtype-selective ligands Effects in vitro and in vivo by apomorphine in the rat corpus cavernosum A structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design A single glycine in extracellular loop 1 is the critical determinant for pharmacological specificity of dopamine D2 and D3 receptors. Three amino acids in the D2 dopamine receptor regulate selective ligand function and affinity. Crystal structure of dopamine receptor D4 bound to the subtype selective ligand, L745870 Current therapeutic molecules and targets in neurodegenerative diseases based on in silico drug design. D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation Ring substituents on substituted benzamide ligands indirectly mediate interactions with position 7.39 of transmembrane helix 7 of the D4 dopamine receptor What can crystal structures of aminergic receptors tell us about designing subtype-selective ligands? The azulene framework as a novel arene bioisostere: design of potent dopamine D4 receptor ligands inducing penile erection A Complete Assessment of Dopamine Receptor- Ligand Interactions through Computational Methods Designing human m1 muscarinic receptor-targeted hydrophobic eigenmode matched peptides as functional modulators Regulation of dopamine D2 receptor expression in grass carp pituitary cells: a possible mechanism for dopaminergic modification of luteinizing hormone synthesis
is cites work of	wds:Q33615741-48C0D884-BAF6-4A54-BABB-5829DD624E6D wds:Q33890919-9E12AA6A-78CC-4B2C-AE0B-41FF0DF7C91A wds:Q34179300-2C52E53D-E8FC-4A11-8294-766F8F09852F wds:Q36105365-74E91EDB-3CFA-4FAD-A208-89B319D29FD3 wds:Q39411714-EF9BE210-8775-4433-A7FF-6630338995B2 wds:Q46137779-1E4803AB-4F81-4F00-873F-AB3415F7FEC1 wds:Q64114044-ADC5D518-5FA8-4725-9DBE-B5036EB2746C wds:Q83227375-9C9D95E5-C611-4296-81E9-5D06D719693B wds:Q34785448-B4236005-21B0-47FD-BB7E-BB48012DE0DE wds:Q52654614-BDCBFB97-9F7D-4561-832B-CE14F5705F5D wds:Q37094875-07744091-FF82-4C4B-9175-5BA808EDD847 wds:Q74818940-3EFD694A-570F-49B9-9B4C-2788C9787980 wds:Q28480436-FB9BCA3D-0D00-4FCA-8311-42F14B98A0DB

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 193 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software