About: Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells

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About: Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells Goto Sponge NotDistinct Permalink

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scientific article published on 01 November 2000

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в листопаді 2000 (uk) article scientifique publié en 2000 (fr) im November 2000 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en payares de 2000 (ast) scientific article published on 01 November 2000 (en)
publication date	wds:Q73141815-1B667162-3971-4739-B2D8-5C55899FFA8C
publication date	2000-11-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73141815-588B2B52-1205-444C-8E39-C4CC17DFB1FA
language of work or name	English
cites work	wds:Q73141815-005FB82D-093F-43FF-A8E8-DADD444979B3 wds:Q73141815-0A6AAFAB-C65A-40E6-85B4-5DBCCD7EF3F6 wds:Q73141815-42006FC9-FDB2-4F6F-A80D-143EAEC2411E wds:Q73141815-52474A6B-4C3B-4408-886A-88E831F9D331 wds:Q73141815-6930B565-3516-4F12-B62C-4368270956FD wds:Q73141815-755949FE-2C4A-448D-9A13-10B05D13AF70 wds:Q73141815-8238E580-DBBF-4E39-93D5-DC8B957DCC3D wds:Q73141815-9DA1AA08-77C3-49CA-96AD-150054AB6B89 wds:Q73141815-9E209754-4106-48A1-BAA4-297F4A39D25C wds:Q73141815-AEA6737F-BAE4-41F5-BD2E-688F89DDEC59 wds:Q73141815-C3D05B40-8C52-4D4B-A34F-2F5EF0ADFCFC wds:Q73141815-D945048E-EEFD-4ACD-9CEB-CB225E6B552F
cites work	The crystal structure of a human nucleoside diphosphate kinase, NM23-H2 A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase. Nm23-transfected MDA-mB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: A31P nuclear magnetic resonance study in vivo and in vitro Coupling between Catalysis and Oligomeric Structure in Nucleoside Diphosphate Kinase Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells. nm23--relationship to the metastatic potential of breast carcinoma cell lines, primary human xenografts, and lymph node negative breast carcinoma patients NDP-K/nm23 expression in human breast cancer in relation to relapse, survival, and other prognostic factors: an immunohistochemical study Multiple karyotypic abnormalities, including structural rearrangements of 11p, in cell lines from malignant melanomas Expression of NM23 in human melanoma progression and metastasis nm23 protein expression in fine-needle aspirates from breast carcinoma: inverse correlation with cytologic grading, lymph node status, and ploidy Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials Prognostic significance of nm23 protein expression in malignant melanoma. An immunohistochemical study
author name string	wds:Q73141815-2F3E3D35-D3B1-47B2-8CC0-1A77F5817461 wds:Q73141815-3E0425F6-C2FF-4B55-ABA6-5EBFEFA1E392 wds:Q73141815-4E471F4B-9931-43C7-9937-0174F07E896D wds:Q73141815-64111280-E06D-4820-BB19-4BDDC84F4040 wds:Q73141815-9418A5E2-36AF-4547-B016-ACA83503096A wds:Q73141815-AD6AE414-C943-408F-A591-F27D93E6688D wds:Q73141815-C79E14B5-0994-4DE2-A057-ACE6F6DD05C3 wds:Q73141815-F86C8C7B-56D1-4F6B-A9DA-174F33184E2C
author name string	N Prasad J Thomson J M Backer R Abbi V Sidorov C V Hamby C E Mendola C Stauffer
rdfs:label	Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells (en) Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells (nl)
skos:prefLabel	Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells (en) Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells (nl)
name	Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells (en) Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells (nl)
title	wds:Q73141815-219EA316-3E64-4C1E-947E-BE407A89B91A
title	Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells (en)
page(s)	wds:Q73141815-F95F76C4-8706-4FCE-9A71-037D6D6E2C52
page(s)	547-553
instance of	wds:Q73141815-63C9B611-60C6-4576-A929-35B7178DD531
instance of	scholarly article
main subject	wds:Q73141815-73541440-005A-453B-ABF3-9BB87AF2CAF3
main subject	metastatic potential
PubMed ID	wds:Q73141815-8B5E760F-E930-4549-8C3F-7E5F54BB0199
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11058869
PubMed ID	11058869
published in	wds:Q73141815-512DCA55-5A0C-4B8D-80F8-155AF1B85FE8
published in	International Journal of Cancer
issue	wds:Q73141815-8B606924-742B-465D-AC3A-C27CDD084488
volume	wds:Q73141815-7B0A9176-09A3-4725-9457-A50E8E020196
issue	4
volume	88
DOI	wds:Q73141815-27E312A9-2127-45F1-B235-48C585640609
DOI	http://dx.doi.org/10.1002/1097-0215(20001115)88:4%3C547::AID-IJC5%3E3.0.CO;2-L
DOI	10.1002/1097-0215(20001115)88:4<547::AID-IJC5>3.0.CO;2-L
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73141815
is cites work of	Purinergic regulation of angiogenesis by human breast carcinoma-secreted nucleoside diphosphate kinase Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement Purinergic mechanisms in breast cancer support intravasation, extravasation and angiogenesis Nm23-H1 homologs suppress tumor cell motility and anchorage independent growth Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives Cytotoxicity and Selectivity in Skin Cancer by SapC-DOPS Nanovesicles Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation A role for nucleotides in support of breast cancer angiogenesis: heterologous receptor signalling Extracellular NM23 Signaling in Breast Cancer: Incommodus Verum Mechanisms of non-metastatic 2 (NME2)-mediated control of metastasis across tumor types. SLT-VEGF reduces lung metastases, decreases tumor recurrence, and improves survival in an orthotopic melanoma model Regulation of the metastasis suppressor Nm23-H1 by tumor viruses [Construction and expression of nm23-H1 gene with different enzyme activities and resistant specific shRNA in eukaryotic expression vector]. Blockade of extracellular NM23 or its endothelial target slows breast cancer growth and metastasis.
is cites work of	wds:Q38270093-A474DC0D-46A3-4F81-9B5B-4E2061B15B2A wds:Q35546643-0B97A302-AACF-449D-B556-1E96855F3FD6 wds:Q39661859-9AD69157-E9BC-495E-A167-6D148E29F166 wds:Q35006800-EDA6902B-CDEA-4519-85F6-FF499A55191A wds:Q34483458-857F9537-6FBA-4F41-89D3-0510D9231EB8 wds:Q42186165-672272AC-BBFF-4088-85EB-DF892F0F36B5 wds:Q55426895-42EA05D0-D90F-4E2B-BBF7-2DF80021C9D8 wds:Q24292725-903FE4A7-203D-48CD-979D-20344AC5ABF9

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