About: Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

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About: Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs Goto Sponge NotDistinct Permalink

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scientific article published on 01 August 1999

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 1999 (uk) im August 1999 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'agostu de 1999 (ast) scientific article published on 01 August 1999 (en)
publication date	wds:Q73002431-655BC455-BA8C-4EC1-B21A-92E29C8A1DE2
publication date	1999-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73002431-AE3D541E-434D-4EAD-80C7-6881AB761CB8
language of work or name	English
exact match	wds:Q73002431-024EA7C7-CE65-47BC-BD6D-58F97D8E21AA
exact match	https://scigraph.springernature.com/pub.10.1038/sj.onc.1203078
cites work	wds:Q73002431-0F4CBC9C-C017-4746-AC46-1C8A76057C14 wds:Q73002431-1C110A65-45DC-4534-AAD1-5EAF89F89043 wds:Q73002431-1C4A51F7-A1EA-455B-95FF-EFF7AB60208F wds:Q73002431-2C11D08B-2DB4-4D2F-B76C-3E46AA395DED wds:Q73002431-2F78B4FE-0F32-4157-A781-EA36BDDDDD28 wds:Q73002431-30429C4F-8E9A-4BFA-A21F-0F0233802E23 wds:Q73002431-31880B1C-14D4-41B1-9E9E-950A61153C51 wds:Q73002431-3EAAF966-F318-40EB-B5E0-364452E39CB0 wds:Q73002431-416C03CD-38B4-4F38-86F7-E79F531A328E wds:Q73002431-4D8DD38D-58BD-4DE3-B4F6-32623E7BBCF7 wds:Q73002431-5A24E522-DF19-44BF-ABE0-85B4B48EDDC8 wds:Q73002431-655179B1-64C6-44CC-8CE1-B3915C084CC2 wds:Q73002431-67D7A2EE-B76D-47B9-A83C-2145AB9951BE wds:Q73002431-728E4534-2574-4FE8-8A9F-D9499D6D1CB7 wds:Q73002431-7C4986F4-6F81-4B17-8D8F-6B2CF03EEAD5 wds:Q73002431-7C7D0ECD-7E80-4601-86A4-B1F4CD251720 wds:Q73002431-7FE04E45-DA7E-42CD-ABE8-3F9B913DDC25 wds:Q73002431-80E8E43F-FDAD-4F63-BA43-F555772976C4 wds:Q73002431-81B6179C-B426-4315-983C-2A0D9784461F wds:Q73002431-914079A2-9105-4496-A5AD-52B624252B87 wds:Q73002431-AB78AFB4-1F99-4D7F-8FC3-7F3848B6580E wds:Q73002431-ABFAAA35-E7A4-408B-99D6-F6D89D335657 wds:Q73002431-AD18E8C2-FE81-401E-BB0D-A185E476EA87 wds:Q73002431-BAF3B53A-3B99-4920-B9DC-C95E9B50CD89 wds:Q73002431-D35E8C82-8EF0-4BE7-A37E-351CD775B576 wds:Q73002431-E449B0F5-2F09-4370-B928-7A0C53EE4D48 wds:Q73002431-E90BBF58-F912-42F5-9273-9A71AD7719D3 wds:Q73002431-EBB938FD-8F49-4734-B263-423A5BB2A2E7 wds:Q73002431-EF77688F-BFBD-4CC6-B362-0D6954E168FD wds:Q73002431-F2AC40CC-3070-4073-9086-1BB26B33AAC2 wds:Q73002431-F4C7AC37-F8DB-4B5D-A34D-6CF64D88FD4D wds:Q73002431-FA50C127-6A8E-4809-BDE1-9FDE05400D2B
cites work	Genetic analysis of indefinite division in human cells: identification of four complementation groups The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases WAF1, a potential mediator of p53 tumor suppression DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts A biomarker that identifies senescent human cells in culture and in aging skin in vivo Telomerase in human development and cancer Effects of infection rate and selection pressure on gene expression from an internal promoter of a double gene retroviral vector Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains p53-dependent apoptosis modulates the cytotoxicity of anticancer agents Requirement for p53 and p21 to sustain G2 arrest after DNA damage Production of high-titer helper-free retroviruses by transient transfection DNA topoisomerase poisons as antitumor drugs Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a Stable cell membrane labelling Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. DNA damage and p53-mediated cell cycle arrest: a reevaluation. The serial cultivation of human diploid cell strains Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition Senescence of human fibroblasts induced by oncogenic Raf. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21 Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53. Cell-cycle arrest versus cell death in cancer therapy The biology of replicative senescence Inducible retroviral vectors regulated by lac repressor in mammalian cells Apoptosis and mitotic cell death: their relative contributions to normal-tissue and tumour radiation response Lack of cell cycle regulation of telomerase activity in human cells Induction of senescence in human malignant glioma cells by p16INK4A. The cat and mouse games that genes, viruses, and cells play Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs Induction of gene amplification by 5-aza-2'-deoxycytidine Applications of green fluorescent protein as a marker of retroviral vectors
author name string	wds:Q73002431-048BA223-25CA-476F-9F0E-35B582D9A2F9 wds:Q73002431-7C2D9A80-2D6C-44C4-9AD7-B3AECAD02604 wds:Q73002431-B7FA05B7-EA20-4D62-9F82-3DD1A684AB81 wds:Q73002431-D6F5586A-CEF0-4E00-BE10-9362E867445B wds:Q73002431-F1E490AA-4A64-48D6-AB8B-3C285750C003 wds:Q73002431-F5AB0A0F-51F0-4766-99EF-C4CDE72FE821 wds:Q73002431-F7E28347-571A-43E4-AD03-C0D0692C3614
author name string	Zhu H Fang J Roninson IB Schott B Chang BD Broude EV Xuan Y
rdfs:label	Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs (en) Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs (nl)
skos:prefLabel	Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs (en) Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs (nl)
name	Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs (en) Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs (nl)
title	wds:Q73002431-BA7D3D2C-6218-4EF0-BD56-44D235719336
title	Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs (en)
page(s)	wds:Q73002431-359A4560-B16F-4C10-B785-C9B235E14133
page(s)	4808-4818

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