About: Wei Zheng

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group leader in rare and neglected diseases research at National Institutes of Health

Attributes	Values
rdf:type	Item
description	forskare (sv) 研究者 (ja) 研究者 (zh) group leader in rare and neglected diseases research at National Institutes of Health (en)
rdfs:label	Wei Zheng (en) Wei Zheng (nl)
skos:prefLabel	Wei Zheng (en) Wei Zheng (nl)
name	Wei Zheng (en) Wei Zheng (nl)
instance of	wds:Q72868603-f3e5fbf1-47c3-d435-981a-91424b97ea49
instance of	Homo sapiens
ResearchGate profile ID	wds:Q72868603-9FD6BF40-8D24-4991-8DE4-43A8B8B1C71C
ResearchGate profile ID	Wei_Zheng86
occupation	wds:Q72868603-b1fc8cfc-460b-4f51-f8f2-f328e13a4702
employer	wds:Q72868603-6D1815DA-ADEA-4298-8B28-74F4C519ED76 wds:Q72868603-71c7f760-45a5-fd03-60a7-66226012229c wds:Q72868603-8f81f863-45ad-285f-26c3-26bc2e4c1d2d wds:Q72868603-a99b0e8f-4f85-8a7f-b121-36c373cca86f wds:Q72868603-bcf0edb2-40a1-d96c-e5b3-97b30df2be23
on focus list of Wikimedia project	wds:Q72868603-0E00B7BF-3E67-401E-91BC-41255C872D73 wds:Q72868603-DE4C91D9-96B2-4C7A-8903-21AEDB36FD44
educated at	wds:Q72868603-6ce84763-4d61-a85c-92d7-2d0af270df33 wds:Q72868603-b4cde273-47f0-b551-fd04-e07c50d3a8d1
occupation	researcher
employer	University at Buffalo Amgen National Institutes of Health National Center for Advancing Translational Sciences Merck & Co.
on focus list of Wikimedia project	WikiProject COVID-19 WikiProject Zika Corpus
educated at	University at Buffalo Zhejiang University School of Medicine
ORCID iD	wds:Q72868603-3AFA179B-2C4D-4CEE-8654-A4F9B0F3B870
ORCID iD	https://orcid.org/0000-0003-1034-0757
ORCID iD	0000-0003-1034-0757
ResearcherID	wds:Q72868603-266569D2-26B6-4AF9-8E58-86113842EA43
Publons author ID	wds:Q72868603-FD0E8CBC-C87E-4DDD-9C66-AA40823CA46D
ResearcherID	J-8889-2014
Publons author ID	2498144
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q72868603
is author of	Compound Management for Quantitative High-Throughput Screening Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1. Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interaction Multi-gram scale synthesis of FR180204. Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen Inhibition of HERG potassium channels by domiphen bromide and didecyl dimethylammonium bromide Mechanism of HERG potassium channel inhibition by tetra-n-octylammonium bromide and benzethonium chloride A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel Rapid identification of antifungal compounds against Exserohilum rostratum using high throughput drug repurposing screens A high-throughput screening assay for fungicidal compounds against Cryptococcus neoformans High-throughput Giardia lamblia viability assay using bioluminescent ATP content measurements δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders High-Throughput Screening to Identify Compounds That Increase Fragile X Mental Retardation Protein Expression in Neural Stem Cells Differentiated From Fragile X Syndrome Patient-Derived Induced Pluripotent Stem Cells Elabela-apelin receptor signaling pathway is functional in mammalian systems Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy Cardiac glycosides inhibit p53 synthesis by a mechanism relieved by Src or MAPK inhibition High throughput screening for small molecule therapy for Gaucher disease using patient tissue as the source of mutant glucocerebrosidase A high throughput glucocerebrosidase assay using the natural substrate glucosylceramide Discovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase A quantitative high throughput assay for identifying gametocytocidal compounds Chemical signatures and new drug targets for gametocytocidal drug development Phenotypic screens as a renewed approach for drug discovery A high-throughput screening assay for determining cellular levels of total tau protein Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries Novel cell-based hepatitis C virus infection assay for quantitative high-throughput screening of anti-hepatitis C virus compounds High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors An AlphaScreen-based high-throughput screen to identify inhibitors of Hsp90-cochaperone interaction Two high-throughput screening assays for aberrant RNA-protein interactions in myotonic dystrophy type 1. An alternative direct compound dispensing method using the HP D300 digital dispenser High throughput screening for inhibitors of alpha-galactosidase Synthesis and characterization of a new fluorogenic substrate for alpha-galactosidase Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death Increased expression of the cardiac L-type calcium channel in estrogen receptor-deficient mice Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels Scintillation proximity assay of inositol phosphates in cell extracts: high-throughput measurement of G-protein-coupled receptor activation A robotic platform for quantitative high-throughput screening Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice A phenotypic compound screening assay for lysosomal storage diseases A multiplex calcium assay for identification of GPCR agonists and antagonists Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease High-throughput screening assays for the identification of chemical probes Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format Quantitative high-throughput screening using a live-cell cAMP assay identifies small-molecule agonists of the TSH receptor A miniaturized glucocorticoid receptor translocation assay using enzymatic fragment complementation evaluated with qHTS. Molecular signatures associated with ZIKV exposure in human cortical neural progenitors Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays High throughput assay technologies for ion channel drug discovery. High-Throughput Multiplexed Quantitation of Protein Aggregation and Cytotoxicity in a Huntington's Disease Model Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs Drug combination therapy increases successful drug repositioning A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor The pilot phase of the NIH Chemical Genomics Center Selective Modulation of Gq/Gs pathways by Naphtho Pyrano Pyrimidines as antagonists of the Neuropeptide S Receptor Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules. Pharmacological, radioligand binding, and electrophysiological characteristics of FPL 64176, a novel nondihydropyridine Ca2+ channel activator, in cardiac and vascular preparations

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