About: Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A

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About: Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A Goto Sponge NotDistinct Permalink

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scientific article published on 01 December 1993

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 1993 (uk) article scientifique publié en 1993 (fr) im Dezember 1993 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 1993 (ast) scientific article published on 01 December 1993 (en)
publication date	wds:Q72628094-FC58A988-ADFB-4866-A7AD-B01891E832A2
publication date	1993-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q72628094-3B359A8F-B922-413D-B98C-9AEC64A782FD
language of work or name	English
cites work	wds:Q72628094-071C3400-EA67-41EE-BDE8-AF7D67ADFA43 wds:Q72628094-27FB0E06-843B-48EA-B0CF-3811DA35264E wds:Q72628094-377EB277-ADCA-43B1-9528-6A43FA600ABF wds:Q72628094-D4531E19-143B-41A5-A986-6C771E5D0442 wds:Q72628094-D942CC85-F0FC-4C60-8A01-43FA437B90EF wds:Q72628094-FD9B9027-570E-43A8-9D59-336FBAFAC83A
cites work	Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclase-dehydratase-O-methyl transferase Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of polyketide antibiotic biosynthesis. Overproduction and localization of components of the polyketide synthase of Streptomyces glaucescens involved in the production of the antibiotic tetracenomycin C The tcmVI region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens encodes the tetracenomycin F1 monooxygenase, tetracenomycin F2 cyclase, and, most likely, a second cyclase New anthracyclines, feudomycins, produced by the mutant from Streptomyces coeruleorubidus ME130-A4. Anthracycline metabolites from baumycin-producing Streptomyces sp. D788. II. New anthracycline metabolites produced by a blocked mutant strain RPM-5
author name string	wds:Q72628094-43204460-F87F-46FD-B3DA-1F87B0239876 wds:Q72628094-517AA774-D7A8-4B85-9AD0-545F8F0A3705
author name string	C R Hutchinson B Shen
rdfs:label	Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A (en) Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A (nl)
skos:prefLabel	Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A (en) Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A (nl)
name	Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A (en) Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A (nl)
title	wds:Q72628094-D662131B-D9B8-4858-BF7B-4A9960FB831E
title	Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A (en)
page(s)	wds:Q72628094-67357B05-8CB4-4175-A204-2E3CCB64609C
page(s)	1535-1540
instance of	wds:Q72628094-6CEC49A1-912E-42CA-B550-86C8AF44B7A4
instance of	scholarly article
PubMed ID	wds:Q72628094-60082E06-69D0-4D53-9FC5-568B5B142A81
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8248801
PubMed ID	8248801
published in	wds:Q72628094-6493D115-BBAE-42E7-A3D5-18597F3A5C67
published in	Science
issue	wds:Q72628094-2F157262-1D07-4101-B030-D57FA2A3FEA8
volume	wds:Q72628094-928EB8AB-1367-4EBA-9275-7B20CC02ADA1
issue	5139
volume	262
DOI	wds:Q72628094-59D58E1D-C553-4015-A625-DA226D89224A
DOI	http://dx.doi.org/10.1126/SCIENCE.8248801
DOI	10.1126/SCIENCE.8248801
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q72628094
is cites work of	Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis Heterologous expression, purification, reconstitution and kinetic analysis of an extended type II polyketide synthase The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710 Structural control of polyketide formation in plant-specific polyketide synthases Isolation and sequence analysis of polyketide synthase genes from the daunomycin-producing Streptomyces sp. strain C5. A yeast acetyl coenzyme A carboxylase mutant links very-long-chain fatty acid synthesis to the structure and function of the nuclear membrane-pore complex. Identification of a flavin:NADH oxidoreductase involved in the biosynthesis of actinorhodin. Purification and characterization of the recombinant enzyme Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation Cyclization of aromatic polyketides from bacteria and fungi Combinatorial biosynthesis for new drug discovery Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase Identification of a monooxygenase from Streptomyces coelicolor A3(2) involved in biosynthesis of actinorhodin: purification and characterization of the recombinant enzyme Conformational changes associated with the binding of zinc acetate at the putative active site of Xc TcmJ, a cupin from Xanthomonas campestris pv. campestris Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase In Vitro Reconstitution of Metabolic Pathways: Insights into Nature's Chemical Logic Sterigmatocystin biosynthesis in Aspergillus nidulans requires a novel type I polyketide synthase MCAT is not required for in vitro polyketide synthesis in a minimal actinorhodin polyketide synthase from Streptomyces coelicolor Catalytic self-acylation of type II polyketide synthase acyl carrier proteins Drug synthesis by genetically engineered microorganisms Heterologous expression of an engineered biosynthetic pathway: functional dissection of type II polyketide synthase components in Streptomyces species Functional analysis of putative beta-ketoacyl:acyl carrier protein synthase and acyltransferase active site motifs in a type II polyketide synthase of Streptomyces glaucescens Deciphering the mechanism for the assembly of aromatic polyketides by a bacterial polyketide synthase Crp is a global regulator of antibiotic production in streptomyces Achieving natural product synthesis and diversity via catalytic networking ex vivo Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus Huanglongmycin A-C, Cytotoxic Polyketides Biosynthesized by a Putative Type II Polyketide Synthase From Streptomyces sp. CB09001. Acylation of Streptomyces type II polyketide synthase acyl carrier proteins Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic Identification and characterization of a type II peptidyl carrier protein from the bleomycin producer Streptomyces verticillus ATCC 15003. Delineation of gilvocarcin, jadomycin, and landomycin pathways through combinatorial biosynthetic enzymology A putative polyketide-synthesis protein XC5357 from Xanthomonas campestris: heterologous expression, crystallization and preliminary X-ray analysis Special issue of The Journal of Antibiotics dedicated to the late Professor C Richard Hutchinson. Regulatory Patterns of Crp on Monensin Biosynthesis in Streptomyces cinnamonensis
is cites work of	wds:Q28379008-7752C4F3-10A3-4189-933A-6142B7CBF9B9 wds:Q35921735-C2A9FB3D-5736-45C2-ACEF-7D8D427C2B36 wds:Q34760022-2B513B80-CC18-41B1-9591-B0BA03D72CF0 wds:Q40940289-5C71516B-971A-4601-9919-96005F9766F7 wds:Q35932237-44FC5682-7106-424C-8601-019A3F41AC81 wds:Q35577870-DC172A5F-7166-4486-BECF-E09C9DADD0E3 wds:Q36446319-B619648B-DAFB-46D2-9658-AF0E4AA3D70D wds:Q35866989-ECC7FEFB-06D0-4BE0-BE63-DE13C70B97FB wds:Q39931719-3E8A6DF1-D327-4F02-BBD5-A3CE5096F03C wds:Q41681873-E283E080-1B14-42E2-A38B-B0FFF8A0DCC8 wds:Q39835815-3552BCB4-3C50-4A91-B189-D9AB1AF0ED3D wds:Q42905073-4F44C17B-1826-4491-AEB5-152746B80A7E wds:Q33954809-066A68C6-9457-48E1-AE75-ECCC0E9816B2

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