About: Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase

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About: Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase Goto Sponge NotDistinct Permalink

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scientific article published on 01 March 1981

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в березні 1981 (uk) im März 1981 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en marzu de 1981 (ast) scientific article published on 01 March 1981 (en)
publication date	wds:Q72458471-1A9A36F2-2683-4C7F-98A0-724808F58DB2
publication date	1981-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q72458471-3C1312B1-3B82-47FB-B8BB-200D773E5238
language of work or name	English
cites work	wds:Q72458471-0E51E676-FFFB-42D6-A9EE-BF2B20CE6F41 wds:Q72458471-78FB6668-70A3-4F0E-938C-69B3D0DFB9FC wds:Q72458471-8F42627F-7AD9-4663-B542-6372A1F304A2
cites work	Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects Platelet and Blood Vessel Arachidonate Metabolism and Interactions Development and evaluation of a disposable device for performing simultaneous duplicate bleeding time determinations
author name string	wds:Q72458471-0B7837D7-3D0F-4100-BF27-F61AD2302013 wds:Q72458471-531536CF-2178-49EA-A4F6-4136BDD30074 wds:Q72458471-B938B65D-1916-4678-B9C3-840A29340BFE
author name string	C A Saxton H M Tyler M J Parry
rdfs:label	Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase (en) Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase (nl)
skos:prefLabel	Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase (en) Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase (nl)
name	Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase (en) Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase (nl)
title	wds:Q72458471-B7F1430E-DE95-4E54-ABD2-45BB845BC2D2
title	Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase (en)
page(s)	wds:Q72458471-6BA56C49-3E4B-4801-BAE7-7BDDF1F79122
page(s)	629-632
instance of	wds:Q72458471-ADC3962F-AE74-436A-9F30-C5C304C52023
instance of	scholarly article
PubMed ID	wds:Q72458471-890E1709-5442-4318-A8F5-998DF46EB2BC
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/6110861
PubMed ID	6110861
published in	wds:Q72458471-3FCCC3A6-810C-4BB4-8858-721A4B604698
published in	The Lancet
issue	wds:Q72458471-EFA9E1B4-51B3-4393-9BEE-E28D9418FFE3
volume	wds:Q72458471-70B5A448-4BCE-41DC-89BD-6977719711DA
issue	8221
volume	1
DOI	wds:Q72458471-EEEE14B6-0D4B-4232-A7AD-D45AB8747EC1
DOI	http://dx.doi.org/10.1016/S0140-6736(81)91551-8
DOI	10.1016/S0140-6736(81)91551-8
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q72458471
is cites work of	PHARMACOLOGY OF ANTIPLATELET DRUGS AND CLINICAL TRIALS ON THROMBOSIS PREVENTION: A DIFFICULT LINK Eighth Gaddum Memorial Lecture. University of London Institute of Education, December 1980. Biological importance of prostacyclin Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man. Functional role of thromboxane production by acutely rejecting renal allografts in rats Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction Bile salt stimulation of colonic epithelial proliferation. Evidence for involvement of lipoxygenase products Glomerular prostaglandin and thromboxane synthesis in rat nephrotoxic serum nephritis. Effects on renal hemodynamics Role of proaggregatory and antiaggregatory prostaglandins in hemostasis. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism BM 13.177, A SELECTIVE BLOCKER OF PLATELET AND VESSEL WALL THROMBOXANE RECEPTORS, IS ACTIVE IN MAN CGS 12970: a novel, long acting thromboxane synthetase inhibitor Regulation of lymphatic contractility by arachidonate metabolites Thromboxane (Tx) A2 receptor blockade and TxA2 synthase inhibition alone and in combination: comparison of anti-aggregatory efficacy in human platelets Reorientation of prostaglandin endoperoxide metabolism by a thromboxane synthetase inhibitor: in vitro and clinical observations. Inhibition of platelet aggregation and reversal of vasopressin-induced ECG changes by a carboprostacyclin analogue, ONO 41483, in primates Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01). Selective inhibition of thromboxane biosynthesis in human blood mononuclear cells and the effects of mitogen-stimulated lymphocyte proliferation Potentiation by dazoxiben, a thromboxane synthetase inhibitor, of platelet aggregation inhibitory activity of a thromboxane receptor antagonist and of prostacyclin Thromboxane A2 mediates lung vasoconstriction but not permeability after endotoxin Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3′-pyridinylmethyl)benzofuran-2-carboxylate Introduction: thromboxane in biological systems and the possible impact of its inhibition Effects of dazoxiben on transcardiac thromboxane levels and haemodynamics in coronary heart disease Prostaglandins, thromboxanes and leukotrienes in clinical medicine Selective inhibition of thromboxane synthetase by dazoxiben increases prostacyclin production by leukocytes in angina patients and healthy volunteers Role of platelet antagonists in coronary artery disease: Implications in coronary artery bypass surgery and balloon-catheter dilatation An abnormal pattern of multiple platelet function abnormalities and increased thromboxane generation in patients with primary thrombocytosis and thrombotic complications Effects of dazoxiben, an inhibitor of thromboxane synthetase, on forearm vasoconstriction in response to cold stimulation, and on human blood vessel prostacyclin production Renal eicosanoids as determinants of renal function in liver disease Prevention of extension of ischaemic damage following acute myocardial ischaemia by dazoxiben, a new thromboxane synthetase inhibitor Platelet desensitization induced by arachidonic acid is not due to cyclo-oxygenase inactivation and involves the endoperoxide receptor AIDS in a Haitian couple in Paris Dazoxiben, a thromboxane synthetase inhibitor, in the treatment of Raynaud's syndrome: a double-blind trial In vivo allergen tachyphylaxis in guinea pig lung is mediated by endogenous prostaglandin E biosynthesis Specific thromboxane synthetase inhibition and albumin excretion rate in insulin-dependent diabetes Prostanoids in platelet-vascular interactions Beneficial effects of ibuprofen in pacing-induced myocardial ischemia The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. The Effects of a New Thromboxane Synthetase Inhibitor, CGS‐13080, in Man Interrelationships between prostanoids and skin flap survival: A review Changes in the venous compliance by bradykinin and angiotensin II and its significance for the vascular effects of cyclosporine-A Current concepts for a drug-induced inhibition of formation and action of thromboxane A2. Antiplatelet drugs and thrombosis prevention: ticlopidine in perspective Initial impressions of dazoxiben in the treatment of the ischaemic limb Interaction of cyclosporine-A with the renin-angiotensin system in canine veins. Antiplatelet and anticoagulant effects of "HN-11 500," a selective thromboxane receptor antagonist Effects of dazoxiben and low-dose aspirin on platelet behaviour in man. The effects of dazoxiben, an inhibitor of thromboxane synthetase, on cold-induced forearm vasoconstriction and platelet behaviour in different individuals Dazoxiben: a pharmacological tool or clinical candidate? Raised plasma thromboxane B2 levels in alcoholic liver disease Effects of thromboxane synthetase inhibition on arachidonate metabolism and platelet behaviour Dazoxiben in stable angina A comparative study of the involvement of the prostaglandin H2/thromboxane A2 pathway in intravascular platelet aggregation in guinea-pigs and rats Hemostatic abnormalities in nephrotic syndrome Changes in plasma and urinary 11-dehydrothromboxane B2 in healthy subjects produced by oral CS-518, a novel thromboxane synthase inhibitor

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