About: Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific article published on 01 December 1996

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 1996 (uk) im Dezember 1996 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 1996 (ast) scientific article published on 01 December 1996 (en)
publication date	wds:Q71864916-EC519161-8218-4FD7-8C26-3DD0A12657A9
publication date	1996-12-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q71864916-10500693-5E6A-4EE4-A4D5-AE41666E5F5A wds:Q71864916-7295CFBE-D378-451C-9381-32931A89114A wds:Q71864916-7302E848-1328-43C9-B0A8-B5AA50E5154A wds:Q71864916-7BECAD92-A661-4F0D-8D84-7A8CF3F8A867 wds:Q71864916-8D296728-C671-47C2-9A06-0F6A02B56EDC wds:Q71864916-A6BC8967-1151-4B01-8653-02E9485C426B wds:Q71864916-BD266F3E-7F64-46BF-93CF-87738828EFE8
author name string	D Cosgrove R Sayers J M Kornak W J Hunter J A Grunkemeyer D T Meehan G C Samuelson
rdfs:label	Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome (en) Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome (nl)
skos:prefLabel	Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome (en) Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome (nl)
name	Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome (en) Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome (nl)
title	wds:Q71864916-0B4FC8B9-5FC3-44AE-8D5A-8B1C2F720691
title	Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome (en)
page(s)	wds:Q71864916-E1978109-D569-4050-9571-2A2673BBC7B2
page(s)	2981-2992
instance of	wds:Q71864916-79602D67-849F-4AC6-ACBB-024A5C0825D0
instance of	scholarly article
main subject	wds:Q71864916-73D702A2-8365-407B-B9B9-FCF154050A66
main subject	Alport syndrome
PubMed ID	wds:Q71864916-DFC19308-71E6-485F-8816-4C1A66A16823
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8956999
PubMed ID	8956999
published in	wds:Q71864916-134732C9-0E66-4EFF-9D47-7C3EB204D6A6
published in	Genes & Development
issue	wds:Q71864916-B17FAE13-3132-4423-9A0F-19C30F942ED0
volume	wds:Q71864916-CFF47192-2C0E-411C-8473-83E35DABBB18
issue	23
volume	10
DOI	wds:Q71864916-1F2B5879-0F62-45E0-B0F3-BCF3E5F3129A
DOI	http://dx.doi.org/10.1101/GAD.10.23.2981
DOI	10.1101/GAD.10.23.2981
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q71864916
is cites work of	Epithelial-mesenchymal transition and its implications for fibrosis Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy The extracellular matrix in development and morphogenesis: a dynamic view Basement membranes: structure, assembly and role in tumour angiogenesis Inhibition of tumor angiogenesis by tumstatin: insights into signaling mechanisms and implications in cancer regression Collagens: building blocks at the end of the development line. Laminin α2-mediated focal adhesion kinase activation triggers Alport glomerular pathogenesis X-Linked Alport Dogs Demonstrate Mesangial Filopodial Invasion of the Capillary Tuft as an Early Event in Glomerular Damage Biomechanical strain causes maladaptive gene regulation, contributing to Alport glomerular disease An update on the pathomechanisms and future therapies of Alport syndrome Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease New functional roles for non-collagenous domains of basement membrane collagens Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse. Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease Role for macrophage metalloelastase in glomerular basement membrane damage associated with alport syndrome Understanding hereditary diseases using the dog and human as companion model systems Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain Longitudinal evaluation of FGF23 changes and mineral metabolism abnormalities in a mouse model of chronic kidney disease Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation Glomerular expression of type IV collagen chains in normal and X-linked Alport syndrome kidneys Upregulated expression of integrin α1 in mesangial cells and integrin α3 and vimentin in podocytes of Col4a3-null (Alport) mice Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly Development of kidney glomerular endothelial cells and their role in basement membrane assembly Glomerular proteinuria: a complex interplay between unique players In vivo expression of putative LMX1B targets in nail-patella syndrome kidneys Transcriptional induction of slit diaphragm genes by Lmx1b is required in podocyte differentiation Rapid identification of a disease allele in mouse through whole genome sequencing and bulk segregation analysis Characterization of alpha1(IV) collagen mutations in Caenorhabditis elegans and the effects of alpha1 and alpha2(IV) mutations on type IV collagen distribution Multipotent mesenchymal stem cells reduce interstitial fibrosis but do not delay progression of chronic kidney disease in collagen4A3-deficient mice. Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity The lens capsule Stem cell therapies benefit Alport syndrome Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome. A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers Searching for a treatment for Alport syndrome using mouse models Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice. Irradiation prolongs survival of Alport mice α1β1 integrin/Rac1-dependent mesangial invasion of glomerular capillaries in Alport syndrome Cellular origins of type IV collagen networks in developing glomeruli. Feasibility of repairing glomerular basement membrane defects in Alport syndrome Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome Renal protective effects of aliskiren beyond its antihypertensive property in a mouse model of progressive fibrosis Strial marginal cells play a role in basement membrane homeostasis: in vitro and in vivo evidence Ultrastructural, physiological, and molecular defects in the inner ear of a gene-knockout mouse model for autosomal Alport syndrome. Type IV collagen is detectable in most, but not all, basement membranes of Caenorhabditis elegans and assembles on tissues that do not express it Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 188 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software