About: Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain

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About: Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain Goto Sponge NotDistinct Permalink

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scientific article published on 01 November 1996

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в листопаді 1996 (uk) article scientifique publié en 1996 (fr) im November 1996 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en payares de 1996 (ast) scientific article published on 01 November 1996 (en)
publication date	wds:Q71825162-0351E3DF-290B-4652-968C-9166EE8B427B
publication date	1996-11-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q71825162-2E7D5F9A-6DDB-4ABC-AA06-F1A0579B230D
language of work or name	English
cites work	wds:Q71825162-15F0147B-FE37-4A40-8BE8-63494A704D7F wds:Q71825162-21DB10D0-BC8B-4105-8ABD-15A1745E0FC4 wds:Q71825162-35966EA6-BE63-4BBA-8F8C-9A057C8F9D55 wds:Q71825162-37ABF9B1-0837-4948-A53F-AB7E6CD9FFF5 wds:Q71825162-52087E73-FAC0-41FB-8DC1-DBB65E22B967 wds:Q71825162-5A992C74-01A3-4F64-AB4A-CD7233FD06F0 wds:Q71825162-602DA12D-48B6-425F-9AD0-1F1918CE87F0 wds:Q71825162-677352FA-55D0-4E58-B784-8851B33DF6BA wds:Q71825162-6B91F1E4-F663-48E6-87AC-CDFC4CB642B6 wds:Q71825162-8A976BA1-ED13-47C8-8CA0-3F766082C258 wds:Q71825162-9195F022-1EF0-463B-9DDB-185C85CA3E68 wds:Q71825162-990B0B23-80D6-4A63-9A3B-9CF52AD9D072 wds:Q71825162-9F33DD8F-2BE9-4A45-A285-4F3BB93BB208 wds:Q71825162-AF1FC2F4-2892-43C3-AC17-2FA78849896C wds:Q71825162-B6970B83-7B0F-410C-A218-5BE0A4F7ED45 wds:Q71825162-C88C96B1-960F-45CB-8FA8-208F6DCDA631 wds:Q71825162-DF55B28B-E314-40CB-AFEA-78464323FB37 wds:Q71825162-E1D343B4-4C89-469F-871C-CC9F4794D75F wds:Q71825162-FA35389A-6C9A-4B5E-AAEB-575E23A320C8
cites work	The C-terminal region of membrane type matrix metalloproteinase is a functional transmembrane domain required for pro-gelatinase A activation PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity Thrombin induces the activation of progelatinase A in vascular endothelial cells. Physiologic regulation of angiogenesis Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease Maximal expression of recombinant cDNAs in COS cells for use in expression cloning Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family A matrix metalloproteinase expressed on the surface of invasive tumour cells Furin-dependent intracellular activation of the human stromelysin-3 zymogen cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment Matrix metalloproteinases: a review Proteolytic processing of the alpha-subunit of rat endopeptidase-24.18 by furin. Mutation of the active site glutamic acid of human gelatinase A: effects on latency, catalysis, and the binding of tissue inhibitor of metalloproteinases-1. Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membranes Identification of a monoclonal antibody specific for a neoantigenic determinant on alpha 2-macroglobulin: use for the purification and characterization of binary proteinase-inhibitor complexes
author name string	wds:Q71825162-20B5D540-9CD4-435B-8DD0-B704C3BD28BF wds:Q71825162-3C2644C1-F1F6-4837-B72D-FCEFABDC907C wds:Q71825162-DA49A96E-C7DE-41C5-9943-3172DDA674B0 wds:Q71825162-E6B939A7-F200-4709-8A38-FA7F0A7DE790
author name string	J Cao A Rehemtulla S Zucker W Bahou
rdfs:label	Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain (en) Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain (nl)
skos:prefLabel	Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain (en) Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain (nl)
name	Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain (en) Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain (nl)
title	wds:Q71825162-78005901-CC97-42E4-93D5-D81ED5954EB2
title	Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain (en)
page(s)	wds:Q71825162-3F8D0C09-F7E4-4DA9-AFC4-8917A67FAC87
page(s)	30174-30180
instance of	wds:Q71825162-174A6B76-9092-43EC-975E-3C5502E37AF2
instance of	scholarly article
PubMed ID	wds:Q71825162-68AAA01E-B604-4E92-B40A-DF744F65241F
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8939968
PubMed ID	8939968
published in	wds:Q71825162-2F3448F1-BAC4-4582-A7B6-B7A9406D7381
published in	Journal of Biological Chemistry
issue	wds:Q71825162-B27C24C7-620D-42C3-B702-3AE51E15A2CF
volume	wds:Q71825162-903D57E6-9BC4-4B7C-A6E2-21C4AC4F68B9
issue	47
volume	271
DOI	wds:Q71825162-6E166501-07AF-49E3-9EFC-BC604D209A22
DOI	http://dx.doi.org/10.1074/JBC.271.47.30174
DOI	10.1074/JBC.271.47.30174
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q71825162
is cites work of	Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer A critical role for the membrane-type 1 matrix metalloproteinase in collagen phagocytosis Physiology and pathophysiology of matrix metalloproteases. Control of matrix metalloproteinase catalytic activity Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity A small-molecule furin inhibitor inhibits cancer cell motility and invasiveness Membrane-type matrix metalloproteinases (MT-MMPs): expression and function during glioma invasion The propeptide domain of membrane type 1-matrix metalloproteinase acts as an intramolecular chaperone when expressed in trans with the mature sequence in COS-1 cells The propeptide domain of membrane type 1 matrix metalloproteinase is required for binding of tissue inhibitor of metalloproteinases and for activation of pro-gelatinase A Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases MMP2 activation by collagen I and concanavalin A in cultured human hepatic stellate cells Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions Leukocyte cell surface proteinases: regulation of expression, functions, and mechanisms of surface localization Gamma-irradiation induces matrix metalloproteinase II expression in a p53-dependent manner Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivo Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptides Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-kappa B

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