About: Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family

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About: Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family Goto Sponge NotDistinct Permalink

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scientific article published on 01 November 1996

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в листопаді 1996 (uk) article scientifique publié en 1996 (fr) im November 1996 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en payares de 1996 (ast) scientific article published on 01 November 1996 (en)
publication date	wds:Q71762909-809060BD-ABF6-4439-994F-D8756ADBF5C1
publication date	1996-11-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q71762909-FD62F2A0-EE88-4083-AE21-94662025E0CC
language of work or name	English
cites work	wds:Q71762909-C14EBFCF-2D06-417D-B67D-4FACDC8CD484
cites work	ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation
author name string	wds:Q71762909-0327F233-C08D-4DD7-8C30-385E2A222212 wds:Q71762909-19BCAEED-46E7-492F-958F-8FD0496D27CE wds:Q71762909-7466E984-6981-4B38-BB97-DC388EA7E98F wds:Q71762909-B94CE015-F4F2-4720-A637-DF51035F11A1 wds:Q71762909-BFF8FE94-6E44-469C-9EEB-700A84AA96E6 wds:Q71762909-C000714E-E175-4A8B-B708-7435608CCF01
author name string	J S Gutkind T Miki H Miyata H Teramoto O A Coso T Igishi
rdfs:label	Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family (en) Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family (nl)
skos:prefLabel	Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family (en) Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family (nl)
name	Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family (en) Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family (nl)
title	wds:Q71762909-3D90C379-99AE-4EB6-97FE-A7DD0A6E5D36
title	Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family (en)
page(s)	wds:Q71762909-BB35B4F2-E4AE-4CE9-BC23-84C3D27F9159
page(s)	27225-27228
instance of	wds:Q71762909-670077C3-73FE-4498-A812-9AE56EA1DCA0
instance of	scholarly article
PubMed ID	wds:Q71762909-EC384B1C-E1A5-41A0-98C6-82DA39B070AC
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8910292
PubMed ID	8910292
published in	wds:Q71762909-358DEA2E-579A-4F0C-A301-3E7998830E8C
published in	Journal of Biological Chemistry
issue	wds:Q71762909-82A9235C-BC0F-498D-AA9D-652F5E934FF1
volume	wds:Q71762909-98636CBC-1C02-4023-B888-98946E70A899
issue	44
volume	271
number of pages	wds:Q71762909-4D435498-BC62-4A63-9E92-4018BD8DADD4
number of pages	4 (xsd:decimal)
DOI	wds:Q71762909-82A7431E-8F96-4A6D-AA8B-911EE1DF2187
DOI	http://dx.doi.org/10.1074/JBC.271.44.27225
DOI	10.1074/JBC.271.44.27225
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q71762909
is cites work of	Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas SPECs, small binding proteins for Cdc42 Regulation of mixed lineage kinase 3 is required for Neurofibromatosis-2-mediated growth suppression in human cancer Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase Evidence for a role of mixed lineage kinases in neuronal apoptosis Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: a MLK-3-MKK7-dependent mechanism G protein regulation of MAPK networks The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation Autoinhibition of mixed lineage kinase 3 through its Src homology 3 domain Mixed-lineage kinase control of JNK and p38 MAPK pathways Genome-wide expression changes induced by HTLV-1 Tax: evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-kappaB activation. Annexin A2 silencing induces G2 arrest of non-small cell lung cancer cells through p53-dependent and -independent mechanisms. MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42 A member of the Ste20/PAK family of protein kinases is involved in both arrest of Xenopus oocytes at G2/prophase of the first meiotic cell cycle and in prevention of apoptosis Glycogen synthase kinase-3 regulates cytoskeleton and translocation of Rac1 in long cellular extensions of human keratinocytes Coordinate activation of activator protein 1 and inflammatory cytokines in response to Neisseria gonorrhoeae epithelial cell contact involves stress response kinases. PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3 Differential regulation of mitogen-activated protein kinase kinase 4 (MKK4) and 7 (MKK7) by signaling from G protein beta gamma subunit in human embryonal kidney 293 cells Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases Rho GTPases and their effector proteins Rho signals to cell growth and apoptosis Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck. Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance MEK kinase 2 binds and activates protein kinase C-related kinase 2. Bifurcation of kinase regulatory pathways at the level of an MAPK kinase kinase POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. Identification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinase The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway Carcinogenic metals and NF-kB activation S-nitrosylation of mixed lineage kinase 3 contributes to its activation after cerebral ischemia Dissecting JNK signaling, one KKKinase at a time. Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis Stimulus-specific requirements for MAP3 kinases in activating the JNK pathway Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activation The mixed lineage kinase DLK is oligomerized by tissue transglutaminase during apoptosis Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP.

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