About: Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes

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About: Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes Goto Sponge NotDistinct Permalink

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scientific article published on 01 May 1996

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в травні 1996 (uk) im Mai 1996 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en mayu de 1996 (ast) scientific article published on 01 May 1996 (en)
publication date	wds:Q71072314-841D75C8-10C8-4E80-ACCB-9D5D648FFC6D
publication date	1996-05-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q71072314-787BC073-6049-4E92-8597-CE42A676F1A5
language of work or name	English
author name string	wds:Q71072314-410E68C8-825C-4694-A5F4-CD8BF562CCAE wds:Q71072314-60C6A8D0-A8C1-424D-B7BA-48A3145830C2 wds:Q71072314-65537B40-BE35-4178-872D-7AF2614F8C36 wds:Q71072314-786C2570-B8AF-4720-8E40-81781A407595 wds:Q71072314-8504ECE6-A0FC-46C0-9F37-82A4BC7A5DBE wds:Q71072314-8E294895-301C-4BE5-8846-D6606F0D9C01 wds:Q71072314-91034460-41B8-4D87-8555-4EF2FC640D3C wds:Q71072314-92AE4150-4D65-488F-8CB2-089DCE1FA3FF wds:Q71072314-E0B1EA53-BD6D-4F76-97B1-06B455679D37 wds:Q71072314-EEC05220-55E4-46B2-96D1-ED086E52261F
author name string	K Inoue T Yamamoto T Kamataki K Nagashima M Nakajima N Shimada T Yokoi Y Funae Y Kuroiwa K Nunoya
rdfs:label	Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes (en) Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes (nl)
skos:prefLabel	Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes (en) Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes (nl)
name	Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes (en) Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes (nl)
title	wds:Q71072314-AF085543-A68C-4712-9B83-B604C88A23F5
title	Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes (en)
page(s)	wds:Q71072314-1D9B4B68-33A8-4147-B8F2-AD8D1A66C40D
page(s)	1010-1015
instance of	wds:Q71072314-4F3DD4A7-1961-494D-83C6-3DE895204938
instance of	scholarly article
PubMed ID	wds:Q71072314-6DDA3B45-95E3-455B-88C7-50136E8ADD81
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8627511
PubMed ID	8627511
published in	wds:Q71072314-D3965D4C-C692-41DA-8B1F-14C08203E5AD
published in	Journal of Pharmacology and Experimental Therapeutics
issue	wds:Q71072314-CA5C0278-627E-4865-B1AC-EBE98857D882
volume	wds:Q71072314-8BC87FA1-5F8C-41C5-BE0D-0CBDFD153192
issue	2
volume	277
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q71072314
is cites work of	Positive and negative effects of alcohol and nicotine and their interactions: a mechanistic review. Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. The contribution of common genetic variation to nicotine and cotinine glucuronidation in multiple ethnic/racial populations The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans The contribution of common UGT2B10 and CYP2A6 alleles to variation in nicotine glucuronidation among European Americans Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity A novel CYP2A6 allele, CYP2A623, impairs enzyme function in vitro and in vivo and decreases smoking in a population of Black-African descent A novel CYP2A6 allele (CYP2A635) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism Nicotine self-administration in mice is associated with rates of nicotine inactivation by CYP2A5. Toxicity of nicotine by repeated intratracheal instillation to f344 rats Genetic polymorphism of drug metabolizing enzymes: new mutations in CYP2D6 and CYP2A6 genes in Japanese Pharmacogenetics: a tool for identifying genetic factors in drug dependence and response to treatment Determination of the nicotine metabolites cotinine and trans-3'-hydroxycotinine in biologic fluids of smokers and non-smokers using liquid chromatography-tandem mass spectrometry: biomarkers for tobacco smoke exposure and for phenotyping cytochrome Assessing dimensions of nicotine dependence: an evaluation of the Nicotine Dependence Syndrome Scale (NDSS) and the Wisconsin Inventory of Smoking Dependence Motives (WISDM) Population pharmacokinetics of lumefantrine in pregnant women treated with artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria Effects of nicotine on cytochrome P450 2A6 and 2E1 activities Smokescreen: a targeted genotyping array for addiction research Polymorphisms of CYP2A6 and its practical consequences Known and novel sources of variability in the nicotine metabolite ratio in a large sample of treatment-seeking smokers CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation Utility and relationships of biomarkers of smoking in African-American light smokers. Orally formulated artemisinin in healthy fasting Vietnamese male subjects: a randomized, four-sequence, open-label, pharmacokinetic crossover study CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ion The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intake. Pharmacogenetic Optimization of Smoking Cessation Treatment Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation Stability of the nicotine metabolite ratio in smokers of progressively reduced nicotine content cigarettes Trans-3'-hydroxycotinine: disposition kinetics, effects and plasma levels during cigarette smoking Genetic influences on individual differences in nicotine glucuronidation Population pharmacokinetics of nicotine and its metabolites I. Model development Emerging genetics of COPD. Menthol cigarette smoking and obesity in young adult daily smokers in Hawaii Nicotine Metabolism in Young Adult Daily Menthol and Nonmenthol Smokers The genetics of substance dependence Catalog of 680 variations among eight cytochrome P450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6 Predictors of cessation in African American light smokers enrolled in a bupropion clinical trial Associations Between Genetic Ancestries and Nicotine Metabolism Biomarkers in the Multiethnic Cohort Study Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries. Novel CYP2A6 variants identified in African Americans are associated with slow nicotine metabolism in vitro and in vivo Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences Nicotine exposure and metabolizer phenotypes from analysis of urinary nicotine and its 15 metabolites by LC-MS. The Value of Biosamples in Smoking Cessation Trials: A Review of Genetic, Metabolomic, and Epigenetic Findings

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