About: Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome

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About: Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 1996

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) articolo scientifico (pubblicato il 1996) (it) наукова стаття, опублікована в січні 1996 (uk) im Januar 1996 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 1996 (ast) artikull shkencor i botuar më 01 janar 1996 (sq) scientific article published on 01 January 1996 (en)
publication date	wds:Q70984706-23848BC3-EA94-4EA2-A025-C6FCC2DBD055
publication date	1996-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q70984706-E7D2C29F-B254-40B0-AC1F-000014347789
language of work or name	English
cites work	wds:Q70984706-0FB24F21-CF7A-4D69-85C3-1DD94DB3C3D2 wds:Q70984706-153647D4-1744-430D-8A56-FA7C826FA498 wds:Q70984706-1676632D-9956-4F8C-BA5B-7A1A3E7C7B39 wds:Q70984706-332106A2-FB97-4F84-BE24-D66987A666C2 wds:Q70984706-34FD8FCB-CA11-4DA5-BB30-E95B24BC2E4B wds:Q70984706-35343AE8-2709-4C8E-AF94-EB2F1B8F795D wds:Q70984706-45256F3F-0CAF-46FF-A179-B89E2F9EDF90 wds:Q70984706-5A7A7D5F-B549-45EC-ABAD-71892E765E13 wds:Q70984706-5E8FF28B-A48C-4CDC-AA76-92908735DFF0 wds:Q70984706-60468B19-E7AB-433C-921A-4579DB8E0FE2 wds:Q70984706-7C9F7F3E-566A-4DC7-9AD0-313A27C2F582 wds:Q70984706-A325E615-9101-4A69-88F9-A4384502A73B wds:Q70984706-ADAA3884-4575-4B8C-912B-206BDE8A461A wds:Q70984706-B9C8E64D-40A2-496E-8A45-5ECB633A2D78 wds:Q70984706-BAC207E7-7DD2-40B0-BE62-77A7215C8015 wds:Q70984706-BF2B4888-187E-471C-8515-77EB8BAF256B wds:Q70984706-C6B95E3E-1FE9-4003-A606-40461129849F wds:Q70984706-C748E547-CAF4-4435-8E2A-36506EFA6311 wds:Q70984706-D1A98141-49BA-4FA3-8483-233C22D57B02 wds:Q70984706-D39C6902-0BEE-41C9-8ECF-669DAE96BEEE wds:Q70984706-DC1981AE-0601-41EF-B7D8-6C82FCB152CF wds:Q70984706-DE5CB385-94AE-4125-9969-3FC916AC09EA wds:Q70984706-E542CF6C-1E65-46F7-AF4D-A59870E3A0F3 wds:Q70984706-F5BB4015-CBD4-4228-ADA2-89FA20438F9B
cites work	A point mutation in the mitochondrial tRNA(Leu)(UUR) gene in MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes). Nicotinamide pharmacokinetics in humans and mice: a comparative assessment and the implications for radiotherapy Diseases of the mitochondrial DNA. The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation Sequences of 20 subunits of NADH:ubiquinone oxidoreductase from bovine heart mitochondria. Application of a novel strategy for sequencing proteins using the polymerase chain reaction The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains Sequences of 20 subunits of NADH: Ubiquinone oxidoreductase from bovine heart mitochondria Evaluation of procedures for assaying oxidative phosphorylation enzyme activities in mitochondrial myopathy muscle biopsies Two novel pathogenic mitochondrial DNA mutations affecting organelle number and protein synthesis. Is the tRNA(Leu(UUR)) gene an etiologic hot spot? Pharmacokinetics of nicotinamide and its effect on blood pressure, pulse and body temperature in normal human volunteers Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes Mitochondrial encephalomyopathy (MELAS): pathological study and successful therapy with coenzyme Q10 and idebenone Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate Biochemical studies of skeletal muscle mitochondria. I. Microanalysis of cytochrome content, oxidative and phosphorylative activities of mammalian skeletal muscle mitochondria. MELAS syndrome with mitochondrial tRNA(Leu)(UUR) mutation: correlation of clinical state, nerve conduction, and muscle 31P magnetic resonance spectroscopy during treatment with nicotinamide and riboflavin Mitochondrial encephalomyopathies A simple method for calculating Km and V from a single enzyme reaction progress curve. Synthesis of structurally unstable type III procollagen in patients with cerebral artery aneurysm Subcellular distribution of phosphagens in isolated perfused rat heart Effect of a transaminase inhibitor on the transport of cytosolic reducing equivalents into mitochondria Effects of the radiosensitising agent nicotinamide on relative tissue perfusion and kidney function in C3H mice Respiratory chain activity in tissues from patients (MELAS) with a point mutation of the mitochondrial genome [tRNALeu(UUR) ] Increase in hepatic NAD level--its effect on the redox state and on ethanol and acetaldehyde metabolism
author name string	wds:Q70984706-361BCE91-4392-47F4-8A52-F62999B7B513 wds:Q70984706-70B7D905-DF00-4217-A906-FCF2B532BA0E wds:Q70984706-783EF74F-8663-4E44-8264-13621A4661DD wds:Q70984706-9FE39005-2AA8-4BF3-BA2D-88737E38BC8F wds:Q70984706-CB7A6D1D-39FF-4FCD-9DE2-49E6E0814863
author name string	K Majamaa J Pyhtinen I E Hassinen A M Remes H Rusanen
rdfs:label	Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome (en) Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome (nl) Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome (sq)
skos:prefLabel	Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome (en) Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome (nl) Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome (sq)
name	Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome (en) Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome (nl) Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome (sq)
title	wds:Q70984706-48AABDB1-E58B-4385-9643-D5432FDD9B7E
title	Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome (en)
page(s)	wds:Q70984706-42F44454-391C-4487-AAE8-81DA896FF810
page(s)	691-699
instance of	wds:Q70984706-F7FCA771-3CB9-4DBF-9D7E-712D7344C9B2
instance of	scholarly article
main subject	wds:Q70984706-33CC45F8-52F5-4EFB-A2B4-17900B520136 wds:Q70984706-BD37B590-7195-4AE4-9BFD-64326C1A0059
main subject	wd:Q192423 MELAS syndrome
PubMed ID	wds:Q70984706-BCF06077-2AD5-40AD-B322-D14A77D86E8C
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8594319
PubMed ID	8594319
published in	wds:Q70984706-D1B4CDC2-1B60-43D2-9ACF-100346771A5E
published in	Life Sciences
issue	wds:Q70984706-337C6BE8-9FBA-4DD1-A5F3-286C7019245D
volume	wds:Q70984706-63D9859A-1C21-4FF5-A6D4-830CE2B6C76C
issue	8
volume	58
DOI	wds:Q70984706-D1F6CC31-5875-48F2-82AA-313AEB1E4B63
DOI	http://dx.doi.org/10.1016/S0024-3205(96)80008-7

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