About: The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation

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About: The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 1987

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в січні 1987 (uk) im Januar 1987 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 1987 (ast) 1987 թվականի հունվարի 1-ին հրատարակված գիտական հոդված (hy) artikull shkencor i botuar më 01 janar 1987 (sq) scientific article published on 01 January 1987 (en)
publication date	wds:Q68978483-FF2AAA2B-1D3C-49B2-A25C-65328D34CD6B
publication date	1987-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q68978483-CFE353C3-112A-4107-8F58-431AABC13315
language of work or name	English
cites work	wds:Q68978483-5E93E064-692D-4D84-87F8-DE8729601DE0
cites work	THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS
author name string	wds:Q68978483-87D1FFA3-DB58-4C14-B36C-42C43D34B9CC wds:Q68978483-D3946F0B-7D65-49F3-B690-4654222000E7 wds:Q68978483-EC4A67B2-161E-4C2E-AF12-9EFDBF070141
author name string	M Fox G P Margison D S Fairweather
rdfs:label	The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation (en) The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation (nl) The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation (sq)
skos:prefLabel	The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation (en) The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation (nl) The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation (sq)
name	The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation (en) The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation (nl) The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation (sq)
title	wds:Q68978483-44449DF6-8209-4F70-BE77-E928C085585C
title	The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation (en)
page(s)	wds:Q68978483-AF59B1DF-8305-4F3D-8CAE-7593F692F57D
page(s)	153-159
instance of	wds:Q68978483-AAFE5CFD-BF34-47C0-BC88-CE0DC25AB357
instance of	scholarly article
main subject	wds:Q68978483-C2695814-39A7-4BB3-B0F6-58D43970DB4D
main subject	lifetime
PubMed ID	wds:Q68978483-81CF45AE-6060-4151-AC40-956823921C4D
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2430819
PubMed ID	2430819
published in	wds:Q68978483-392A291B-AB81-46E5-9780-9B3B77E4F3D2
published in	Experimental Cell Research
issue	wds:Q68978483-555C0611-D915-4AFB-ACDC-4CEB0264B726
volume	wds:Q68978483-0569D2BB-CC4D-4255-80C9-63A0172A0618
issue	1
volume	168
DOI	wds:Q68978483-874D1162-C12A-4DA3-99A1-91ABCB7465D6
DOI	http://dx.doi.org/10.1016/0014-4827(87)90424-1
DOI	10.1016/0014-4827(87)90424-1
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q68978483
is cites work of	Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts Effect of ageing on reactivation of the human X-linked HPRT locus UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma Aging, DNA methylation and cancer Ageing. X-chromosome reactivation Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion? Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG Cell aging in vivo and in vitro DNA methylation and epigenetic mechanisms Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent When cells get stressed: an integrative view of cellular senescence WI-38 senescence is associated with global and site-specific hypomethylation Enhanced oxidative stress and accelerated cellular senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts DNA methylation, vernalization, and the initiation of flowering p16/MTS1/INK4A suppresses prostate cancer by both pRb dependent and independent pathways DNA damage and repair during cellular aging Molecular biology of aging Demethylation of classical satellite 2 and 3 DNA with chromosomal instability in senescent human fibroblasts Epigenetic control of cellular senescence in disease: opportunities for therapeutic intervention. Aging and DNA methylation Epigenetic aspects of cellular senescence Changes in DNA methylation patterns and repetitive sequences in blood lymphocytes of aged horses. Synergistic effect of resveratrol and HSV-TK/GCV therapy on murine hepatoma cells Neuroendocrine aging precedes perimenopause and is regulated by DNA methylation Chromatin changes trigger laminin genes dysregulation in aging kidneys. 5-Azacytidine-induced demethyelation of DNA to senescent level does not block proliferation of human fibroblasts Environmental Deflection: The Impact of Toxicant Exposures on the Aging Epigenome. Stable knockdown of PASG enhances DNA demethylation but does not accelerate cellular senescence in TIG-7 human fibroblasts A re-examination of the effects of ionizing radiation on lifespan and transformation of human diploid fibroblasts Experimental approaches to the study of epigenomic dysregulation in ageing Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment Twenty years of ageing research at the Mill Hill laboratories Cell kinetic disturbances induced by treatment of human diploid fibroblasts with 5-azacytidine indicate a major role for DNA methylation in the regulation of the chromosome cycle.
is cites work of	wds:Q33787464-F3F961DD-247A-4FC7-909F-6E8D54A18A61 wds:Q33957508-9FA28DBB-EC54-43D5-8A14-7F7FE5029B5F wds:Q34128610-8D5B8B37-5AA7-4491-931C-5E19E2BADA13 wds:Q38206837-EC7CB4C5-B79A-4A1C-99B3-1434F2911192 wds:Q41561840-DEA0B224-074A-4785-A81E-D848C761A264 wds:Q93370492-E0D1BB08-608A-48D8-A7D4-94A144E55A9A wds:Q41253774-51793205-275F-4B31-8A26-173FD5F289E3 wds:Q64380907-83DE71DB-A53A-406F-A2FA-24EEDE4E4755 wds:Q91766772-1CEF09D7-C3AB-4C64-AAB7-AF37995565DE wds:Q41591692-B7BCA282-5086-42C7-BA23-BC8D5F740D65 wds:Q41811343-25088EDC-0204-431A-9EE8-0368E910E014 wds:Q36043088-01C1D8F6-00C4-45C7-886A-37782DB5D42E wds:Q37632823-ED3CD86C-AB44-43CE-B542-828A91C44823 wds:Q40714842-EE137D98-25CE-48AC-88A4-54DAD29E66C8 wds:Q74297486-1CD22D33-C192-44BD-ABD5-2DB36A51D57C wds:Q33855451-D544B523-DC43-4B47-BA57-8FD1033E348F

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