About: Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer

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About: Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer Goto Sponge NotDistinct Permalink

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scientific article published on 29 August 2019

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) artículu científicu espublizáu n'agostu de 2019 (ast) im August 2019 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована 29 серпня 2019 (uk) scientific article published on 29 August 2019 (en)
publication date	wds:Q68686956-FF2F2644-D88C-43B0-94D4-1B05CF115BE3
publication date	2019-08-29 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q68686956-83F00C7D-DCE9-4E65-9616-5F9BB43EE382
language of work or name	English
cites work	wds:Q68686956-04A6D628-E8FE-4E2E-8D56-04D1C3C30A75 wds:Q68686956-0C932E37-1383-4E90-970E-032608DFF07E wds:Q68686956-0F73B8B3-C826-4C6C-BE29-91977A82D406 wds:Q68686956-11E0B8C8-5A8D-410A-9012-CF7129CBFB6B wds:Q68686956-1ADA5594-3BC7-41D5-A800-D50E0269BE3D wds:Q68686956-2A340BE7-C6E0-496F-8091-6A3E60447176 wds:Q68686956-2E5B9238-7BA7-43E9-88C5-C9DA1020AC4A wds:Q68686956-318AAF06-C1EA-4FF9-A2AE-889A091655AB wds:Q68686956-35364D63-6BFD-44C8-9B90-9E0230EC7070 wds:Q68686956-37E4C2BF-0AAA-4898-A74B-17B996ABB9CC wds:Q68686956-39299C09-54A7-414D-B594-7917CA3F0CDB wds:Q68686956-484B09BE-1A1D-48DF-AEC8-E3472FB570CF wds:Q68686956-4D5281C4-1AE8-403A-8D55-03FB74E6E76E wds:Q68686956-60D77495-0463-4367-BC9D-66398C0CD344 wds:Q68686956-6A11075C-F2A4-4AF8-AEA0-DA6CE89C9442 wds:Q68686956-6B6B7DD5-DF4E-4969-8647-ED3BB768D1D5 wds:Q68686956-6C475A04-0367-4E41-91DD-602D8D5CA05C wds:Q68686956-6E216BC3-4E64-4D2A-BF06-4A9FF45F198F wds:Q68686956-714BFAAC-0D17-48E2-A61F-D84D06D90690 wds:Q68686956-73233534-3DD5-4F76-BB76-DF32E7A7435A wds:Q68686956-7440D451-55CE-4E65-AAD1-A41CDC44184D wds:Q68686956-80280E86-6B64-4BA5-B741-71FDC7A87B19 wds:Q68686956-91D100CE-2D67-4EA5-94E4-FA9B378F78BC wds:Q68686956-94AED2F4-2B5C-4E9D-AEE5-937CF4325ADD wds:Q68686956-A20D3691-49D3-4F51-99E4-CE284A011869 wds:Q68686956-A543B849-4135-46CD-9E51-DD69F1DCAB0C wds:Q68686956-A688B4A8-5B8E-4CC6-8F5D-FAF4EFC7036E wds:Q68686956-A74E8729-8EEC-4036-B960-076B8B5CF286 wds:Q68686956-B5934308-22F0-488A-957F-E4DE98FC8350 wds:Q68686956-CB081678-97D9-4EFA-8A48-21C8D93369FC wds:Q68686956-D43A40CD-56DF-44CE-BD88-B357068E3517 wds:Q68686956-D8502E55-CE71-4684-9902-BB6514C9521D wds:Q68686956-E0E8990C-320F-4E51-B88E-26163BA4794A wds:Q68686956-E125C44D-A79A-4580-9B6C-558BB53D6693 wds:Q68686956-E4282CAD-C83F-4F96-B2D5-E0B69A820E7D wds:Q68686956-E9E1F496-C987-4A9A-8028-6ACF1C9AEB65 wds:Q68686956-F4E7CAF2-5B01-4E9D-BD57-A74F02B09AC8
cites work	Reaction progress kinetic analysis: a powerful methodology for mechanistic studies of complex catalytic reactions Enantioselective carbonyl reverse prenylation from the alcohol or aldehyde oxidation level employing 1,1-dimethylallene as the prenyl donor Rings in drugs Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among U.S. FDA approved pharmaceuticals Creation of quaternary stereocenters in carbonyl allylation reactions Catalytic Enantioselective Addition of Allylic Organometallic Reagents to Aldehydes and Ketones Catalytic asymmetric organozinc additions to carbonyl compounds Industrial methods for the production of optically active intermediates The Enantioselective Addition of Alkyne Nucleophiles to Carbonyl Groups Catalytic Enantioselective Carbonyl Allylation and Propargylation via Alcohol-Mediated Hydrogen Transfer: Merging the Chemistry of Grignard and Sabatier Transition metal catalysis-a unique road map in the stereoselective synthesis of 1,3-polyols Enantioselective Formation of CF3-Bearing All-Carbon Quaternary Stereocenters via C-H Functionalization of Methanol: Iridium Catalyzed Allene Hydrohydroxymethylation. Allenamide hydro-hydroxyalkylation: 1,2-amino alcohols via ruthenium-catalyzed carbonyl anti-aminoallylation anti-Aminoallylation of aldehydes via ruthenium-catalyzed transfer hydrogenative coupling of sulfonamido allenes: 1,2-aminoalcohols Catalytic enantioselective allylation of carbonyl compounds and imines A general, highly enantioselective method for the synthesis of D and L alpha-amino acids and allylic amines Catalytic C-C coupling via transfer hydrogenation: reverse prenylation, crotylation, and allylation from the alcohol or aldehyde oxidation level. Convenient Asymmetric Syntheses of anti-beta-Amino Alcohols The medicinal chemist's toolbox for late stage functionalization of drug-like molecules On the interpretation of deuterium kinetic isotope effects in C-H bond functionalizations by transition-metal complexes Diastereoselective allylation of carbonyl compounds and imines: application to the synthesis of natural products Big Data from Pharmaceutical Patents: A Computational Analysis of Medicinal Chemists' Bread and Butter Applications of Nonenzymatic Catalysts to the Alteration of Natural Products Stereoselective Rh2(S-IBAZ)4-catalyzed cyclopropanation of alkenes, alkynes, and allenes: asymmetric synthesis of diacceptor cyclopropylphosphonates and alkylidenecyclopropanes Organic synthesis provides opportunities to transform drug discovery. Intermolecular Metal-Catalyzed Reductive Coupling of Dienes, Allenes, and Enynes with Carbonyl Compounds and Imines Catalytic nucleophilic 'umpoled' π-allyl reagents. Diastereoselective Allylation of Aldehydes by Dual Photoredox and Chromium Catalysis A Regio- and Enantioselective CuH-Catalyzed Ketone Allylation with Terminal Allenes. Carbonyl anti-(α-Amino)allylation via Ruthenium Catalyzed Hydrogen Autotransfer: Use of an Acetylenic Pyrrole as an Allylmetal Pronucleophile. Cyclometalated Iridium-PhanePhos Complexes Are Active Catalysts in Enantioselective Allene-Fluoral Reductive Coupling and Related Alcohol-Mediated Carbonyl Additions That Form Acyclic Quaternary Carbon Stereocenters Enantioselective Allylation Using Allene, a Petroleum Cracking Byproduct Feedstock Reagents in Metal-Catalyzed Carbonyl Reductive Coupling: Minimizing Preactivation for Efficiency in Target-Oriented Synthesis Enantioselective Synthesis of anti-1,2-Diamines by Cu-Catalyzed Reductive Couplings of Azadienes with Aldimines and Ketimines Amine-promoted asymmetric (4+2) annulations for the enantioselective synthesis of tetrahydropyridines: a traceless and recoverable auxiliary strategy 4-(1,3-Thiazol-2-yl)morpholine derivatives as inhibitors of phosphoinositide 3-kinase 2-Azadienes as Reagents for Preparing Chiral Amines: Synthesis of 1,2-Amino Tertiary Alcohols by Cu-Catalyzed Enantioselective Reductive Couplings with Ketones.
author name string	wds:Q68686956-DF23BF51-FE4A-4EE0-867C-7016BBA9862D wds:Q68686956-FDCF8D70-AC9A-490F-9849-04E77149078E
author name string	Kim Spielmann Leyah A Schwartz
rdfs:label	Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer (en) Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer (nl)
skos:prefLabel	Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer (en) Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer (nl)
name	Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer (en) Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer (nl)
author	wds:Q68686956-A94DBCAA-9077-430D-BC52-45984587A16A wds:Q68686956-B802B231-9839-4E6E-BE98-DDD0F23FE0F4
author	Michael J. Krische Ming Xiang
title	wds:Q68686956-B48AB73B-A929-48F3-9CDA-F5CB2F070DEF
title	Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer (en)

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