About: Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific article published on 01 December 1988

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 1988 (uk) im Dezember 1988 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 1988 (ast) scientific article published on 01 December 1988 (en)
publication date	wds:Q68100604-5F6065D6-E2F0-46E2-AE2B-4A0665068429
publication date	1988-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q68100604-40081B80-34AA-4E8E-9CF1-455E466DAAB1
language of work or name	English
author name string	wds:Q68100604-5505429C-6C4F-416D-965E-DF7FA1F1D326 wds:Q68100604-81A16EC5-741F-402E-A6EB-ED752158104E wds:Q68100604-96120489-DE83-42CC-8A59-FB52C29D4C60 wds:Q68100604-B717EDBD-0B10-4B9E-87DC-569B55043CF4 wds:Q68100604-D975DB21-AB9B-46CA-9E97-6B2F2749D9ED wds:Q68100604-DCA3732F-3CAC-46B8-B6BB-87288BDD4F83 wds:Q68100604-E2F8A0E1-150F-40B1-80DD-041F3813EC14 wds:Q68100604-E3ACECFC-6C94-4B23-985C-E8EA87C9DCCE wds:Q68100604-F862812B-CE28-44A2-83F4-E19D95724FB2
author name string	F R Jirik A J Pollard S A Geller W S Nichols M J Dycaico S W Kohler H P Short J H Hager K Felts
rdfs:label	Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model (en) Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model (nl)
skos:prefLabel	Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model (en) Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model (nl)
name	Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model (en) Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model (nl)
author	wds:Q68100604-3D6259A9-BEC0-4EF3-B784-24E5681A5907
author	Seth G. Grant
title	wds:Q68100604-B0502397-D538-43A1-95AA-AF59D90CFB33
title	Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model (en)
page(s)	wds:Q68100604-52CDA5DE-0A70-41B2-AE04-65DD6D21F529
page(s)	1409-1412
instance of	wds:Q68100604-D58A2E05-C9A1-46E4-A645-2E862CB609AB
instance of	scholarly article
main subject	wds:Q68100604-B45DAEB0-35C5-4FB0-8FE4-A71BA669FF5F
main subject	neonatal hemochromatosis
PubMed ID	wds:Q68100604-4B082D88-846D-40F2-88E7-A9CE6D7A26ED
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/3264419
PubMed ID	3264419
published in	wds:Q68100604-9C8DE2E0-56A3-492C-B929-DE2722DF3E11
published in	Science
issue	wds:Q68100604-FC4CB0B6-51D7-4320-833D-83DB83999A1F
volume	wds:Q68100604-0A931D4E-07AE-4446-A587-B5D7E21CAE3F
issue	4884
volume	242
DOI	wds:Q68100604-0683CE36-E443-46DD-A37E-7C9DE3C39DB1
DOI	http://dx.doi.org/10.1126/SCIENCE.3264419
DOI	10.1126/SCIENCE.3264419
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q68100604
is cites work of	Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver Z α-1 antitrypsin deficiency and the endoplasmic reticulum stress response Alpha1-antitrypsin deficiency. 4: Molecular pathophysiology Liver injury in alpha1-antitrypsin deficiency: an aggregated protein induces mitochondrial injury Selective protein degradation in the yeast exocytic pathway A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency In vivo expression of mammalian BiP ATPase mutants causes disruption of the endoplasmic reticulum Capitalizing on the autophagic response for treatment of liver disease caused by alpha-1-antitrypsin deficiency and other genetic diseases The endosomal protein-sorting receptor sortilin has a role in trafficking α-1 antitrypsin Ribozyme-mediated specific gene replacement of the alpha1-antitrypsin gene in human hepatoma cells The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease. Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. Alpha-1-antitrypsin deficiency: a new paradigm for hepatocellular carcinoma in genetic liver disease Analyses of hepatocellular proliferation in a mouse model of alpha-1-antitrypsin deficiency Indomethacin increases liver damage in a murine model of liver injury from alpha-1-antitrypsin deficiency Chromosomal Elements Regulate Gene Activity and Chromatin Structure of the Human Serpin Gene Cluster at 14q32.1 Liver injury in alpha 1-antitrypsin deficiency Synthesis of stress proteins is increased in individuals with homozygous PiZZ alpha 1-antitrypsin deficiency and liver disease Histopathology of α1-antitrypsin liver disease in a transgenic mouse model Molecular analysis of the gene of the alpha 1-antitrypsin deficiency variant, Mnichinan Utilization of transgenic mice in the study of matrix degrading proteinases and their inhibitors Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections. Prognosis of alpha-1-antitrypsin deficiency-related liver disease in the era of paediatric liver transplantation In vivo post-transcriptional gene silencing of alpha-1 antitrypsin by adeno-associated virus vectors expressing siRNA. Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in alpha-1-antitrypsin deficiency Broad spectrum of hepatocyte inclusions in humans, animals, and experimental models Hepatocarcinogenesis (Z#2)/mutagenesis during initiation stage Liver transplantation for end-stage liver disease associated with alpha-1-antitrypsin deficiency in children: pretransplant natural history, timing and results of transplantation Carpal tunnel syndrome: role of occupation Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice. Comparison of intrahepatic lymphocytes from normal and growth hormone transgenic mice with chronic hepatitis and liver cancer. Hepatic fibrosis and carcinogenesis in α1-antitrypsin deficiency: a prototype for chronic tissue damage in gain-of-function disorders Alpha 1-antitrypsin deficiency Molecular mechanism of hepatocellular injury in alpha 1 antitrypsin deficiency A young woman with cirrhosis: autoimmune hepatitis vs. alpha 1-antitrypsin deficiency Transgenic animals as models for human disease--report of an EC Study Group Using antisense technology to develop a novel therapy for α-1 antitrypsin deficient (AATD) liver disease and to model AATD lung disease PiZ mouse liver accumulates polyubiquitin conjugates that associate with catalytically active 26S proteasomes Targeting intracellular degradation pathways for treatment of liver disease caused by α1-antitrypsin deficiency Pediatric gastroenterology. Update on metabolic liver disease
is cites work of	wds:Q34437066-98B672F8-4822-4C20-9023-722BF9A44AFB

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 196 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software