About: Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

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scientific article published on 01 October 1984

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в жовтні 1984 (uk) article scientifique publié en 1984 (fr) im Oktober 1984 veröffentlichter wissenschaftlicher Artikel (de) scientific article published on 01 October 1984 (en) artículu científicu espublizáu n'ochobre de 1984 (ast)
publication date	wds:Q64390546-FC5BC6EA-A04B-4202-849C-B18AAC00B48A
publication date	1984-10-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q64390546-9AB2A9AC-A367-4708-9DF1-48848E940F64
language of work or name	English
author name string	wds:Q64390546-35655616-9CBA-4828-A2EA-F0BAB8C72925 wds:Q64390546-5030B1DD-A35C-4B2C-92B0-A969CFEFD0D0 wds:Q64390546-8C1E8523-71EF-4C5D-BBE4-383D55C4C675 wds:Q64390546-C236BEBB-075D-484F-80EC-7ECFC441972F
author name string	L Yang L F Liu T C Rowe K M Tewey
rdfs:label	Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II (en) Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II (nl)
skos:prefLabel	Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II (en) Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II (nl)
name	Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II (en) Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II (nl)
author	wds:Q64390546-5B086FC9-7A14-4FF5-96D9-6F07E1A37E21
author	Brian Halligan
title	wds:Q64390546-70B15691-7FC1-40B0-9876-473B543C8E27
title	Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II (en)
page(s)	wds:Q64390546-486F24F0-1720-4D8A-A803-83B6EA7EED0B
page(s)	466-468
instance of	wds:Q64390546-8A24CC40-90FF-4A91-832B-5BF1D5FE02A8
instance of	scholarly article
PubMed ID	wds:Q64390546-11B1EDB4-B345-4116-ABA9-C14720F2B1ED
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/6093249
PubMed ID	6093249
published in	wds:Q64390546-EB903050-4A1E-4CB5-9D8D-98761F99070B
published in	Science
issue	wds:Q64390546-6F2FFFC8-FD8D-4CD7-8B8D-5DA21FB0B6E8
volume	wds:Q64390546-BD98A742-B396-414A-9072-21440E20E3B5
issue	4673
volume	226
DOI	wds:Q64390546-C6935A0E-A304-498B-9542-3714F313927F
DOI	http://dx.doi.org/10.1126/SCIENCE.6093249
DOI	10.1126/SCIENCE.6093249
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q64390546
is cites work of	Novel human topoisomerase I inhibitors, topopyrones A, B, C and D. I. Producing strain, fermentation, isolation, physico-chemical properties and biological activity Cognitive dysfunction induced by chronic administration of common cancer chemotherapeutics in rats Targeted cytotoxic somatostatin analog AN-162 inhibits growth of human colon carcinomas and increases sensitivity of doxorubicin resistant murine leukemia cells. Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats Drugging topoisomerases: lessons and challenges Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress. Implication of prior treatment with drug combinations including inhibitors of topoisomerase II in therapy-related monocytic leukemia with a 9;11 translocation Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide DNA topoisomerase I and II in cancer chemotherapy: update and perspectives A new antitumor agent amrubicin induces cell growth inhibition by stabilizing topoisomerase II-DNA complex. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin Identifying and exploiting defects in the Fanconi anemia/BRCA pathway in oncology. Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity. Swiveling and decatenation of replicating simian virus 40 genomes in vivo Mechanism of action of topoisomerase II-targeted antineoplastic drugs Mitoxantrone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer Down-regulation of growth factor-stimulated MAP kinase signaling in cytotoxic drug-resistant human neuroblastoma cells Combined inhibition of topoisomerases I and II--is this a worthwhile/feasible strategy? Nucleolytic cleavage of the mixed lineage leukemia breakpoint cluster region during apoptosis. Identification of genes required for protection from doxorubicin by a genome-wide screen in Saccharomyces cerevisiae Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice Pim-1 kinase protects hematopoietic FDC cells from genotoxin-induced death Chemical genomics identifies small-molecule MCL1 repressors and BCL-xL as a predictor of MCL1 dependency DNA and its associated processes as targets for cancer therapy Chemoprotectants: a review of their clinical pharmacology and therapeutic efficacy. Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53 ATM-mediated KDM2A phosphorylation is required for the DNA damage repair. Interaction of chromatin-associated Plk1 and Mcm7 Targeting DNA topoisomerase II in cancer chemotherapy Development of a novel assay for human tyrosyl DNA phosphodiesterase 2 p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replication N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes Expression of a mutant DNA topoisomerase II in CCRF-CEM human leukemic cells selected for resistance to teniposide Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence Genetic determinants of response to chemotherapy in transgenic mouse mammary and salivary tumors Caveolin-1 promotes resistance to chemotherapy-induced apoptosis in Ewing's sarcoma cells by modulating PKCalpha phosphorylation Induction of topoisomerase II-mediated DNA cleavage by the plant naphthoquinones plumbagin and shikonin Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment Staphylococcus aureus gyrase-quinolone-DNA ternary complexes fail to arrest replication fork progression in vitro. Effects of salt on the DNA binding mode and the catalytic activity of S. aureus gyrase Clinical applications of anticancer drugs targeted to topoisomerase II DNA topoisomerase II as a target of antineoplastic drug therapy New developments in antitumor anthracyclines. Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs Idarubicin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer Anthracyclines and their C-13 alcohol metabolites: growth inhibition and DNA damage following incubation with human tumor cells in culture Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs The peptide antibiotic microcin B17 induces double-strand cleavage of DNA mediated by E. coli DNA gyrase Etoposide: four decades of development of a topoisomerase II inhibitor Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection

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