About: Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition

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About: Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition Goto Sponge NotDistinct Permalink

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article by Nuala McCabe et al published 15 August 2006 in Cancer Research

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2006 (fr) наукова стаття, опублікована в серпні 2006 (uk) im August 2006 veröffentlichter wissenschaftlicher Artikel (de) article by Nuala McCabe et al published 15 August 2006 in Cancer Research (en)
publication date	wds:Q64388338-8DDF0126-3499-47F9-854F-84DD16FF9E74
publication date	2006-08-15 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q64388338-B0B63169-9EC7-46FE-9B62-DA35C0C9DC50
language of work or name	English
author name string	wds:Q64388338-16F9792B-CB88-499F-A0D5-CD3702D7E100 wds:Q64388338-459E9A59-B7BA-4F1E-A1F1-E89855433A9F wds:Q64388338-83247EB1-F251-4048-B1A3-8C6B08DC9649 wds:Q64388338-8977E7AB-A5A3-4C59-A42C-7C166B7DC13A wds:Q64388338-C506C540-EC76-4389-B491-C115E8FF7C7F wds:Q64388338-F08C674B-9CEB-42A9-BD40-E2A34BB2DFB1 wds:Q64388338-FF45FD49-F4CB-404B-B971-DC4815E42CA2
author name string	Mark J O'Connor Nicholas C Turner Graeme C M Smith Andrew N Tutt Sally Swift Aneta Bialkowska Sabrina Giavara
rdfs:label	Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly (nl) Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition (en)
skos:prefLabel	Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly (nl) Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition (en)
name	Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly (nl) Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition (en)
author	wds:Q64388338-349E7FA6-1B2C-4226-8B20-3C6757699ED2 wds:Q64388338-42B83FFD-C563-457A-8CBC-1BD79C2866E3 wds:Q64388338-A49C0267-4CF6-4F29-BC06-FFFDC383CBA3 wds:Q64388338-D3EAEA65-77C8-4AED-BA6E-A2477BB3DB83 wds:Q64388338-EA447164-4FFD-4632-8FC5-E74B054D3C18
author	Alan Ashworth Christopher J Lord Małgorzata Z Zdzienicka Nuala McCabe Katarzyna Kluzek
title	wds:Q64388338-058156BE-F009-4EFD-A5D4-C563A6792307
title	Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition (en)
page(s)	wds:Q64388338-529B0410-7283-4A65-B30E-A4F9AB7B0D18
page(s)	8109-15
instance of	wds:Q64388338-B821A8D3-C1B0-4959-B21C-217DEC843FD8
instance of	scholarly article
PubMed ID	wds:Q64388338-7BB892E8-8D4C-4D26-9B0A-748DC51CA0FC
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16912188
PubMed ID	16912188
published in	wds:Q64388338-0F7BB426-1080-4654-A330-6B8039566147
published in	Cancer Research
issue	wds:Q64388338-A90DD888-5240-49D7-938D-0B0FDE22B508
volume	wds:Q64388338-A8EED43A-8FA3-4A0B-9D39-44189177E234
issue	16
volume	66
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q64388338
is cites work of	BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group The Elephant and the Blind Men: Making Sense of PARP Inhibitors in Homologous Recombination Deficient Tumor Cells. PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition Loss of ATM kinase activity leads to embryonic lethality in mice PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation. An update on PARP inhibitors for the treatment of cancer Phase II Study of Olaparib (AZD-2281) After Standard Systemic Therapies for Disseminated Colorectal Cancer A phase I combination study of olaparib with cisplatin and gemcitabine in adults with solid tumors. Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors DNA damage tolerance: a double-edged sword guarding the genome Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib Mechanisms of resistance to therapies targeting BRCA-mutant cancers BMN 673, a novel and highly potent PARP1/2 inhibitor for the treatment of human cancers with DNA repair deficiency. RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation A marker of homologous recombination predicts pathologic complete response to neoadjuvant chemotherapy in primary breast cancer Germline BRCA mutation does not prevent response to taxane-based therapy for the treatment of castration-resistant prostate cancer BRCAness revisited Targeting abnormal DNA repair in therapy-resistant breast cancers Targeting abnormal DNA double strand break repair in cancer MicroRNA-182-5p targets a network of genes involved in DNA repair Mutations in Fanconi anemia genes and the risk of esophageal cancer. Mechanisms of chemoresistance to alkylating agents in malignant glioma 53BP1 expression in sporadic and inherited ovarian carcinoma: Relationship to genetic status and clinical outcomes. Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic Landscapes Susceptibility pathways in Fanconi's anemia and breast cancer Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy Strategies for optimizing the response of cancer and normal tissues to radiation The Role of PARP Inhibitors in the Treatment of Gynecologic Malignancies Profile of veliparib and its potential in the treatment of solid tumors Beyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid Tumors Poly (ADP-ribose) polymerase inhibitors: recent advances and future development. Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors An update on PARP inhibitors--moving to the adjuvant setting Chemotherapy and signaling: How can targeted therapies supercharge cytotoxic agents? Modification of the DNA damage response by therapeutic CDK4/6 inhibition A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics. Failure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitro The role of PARP in DNA repair and its therapeutic exploitation PARP inhibition: PARP1 and beyond Synthetic lethal approaches to breast cancer therapy Upregulation of Poly (ADP-Ribose) Polymerase-1 (PARP1) in Triple-Negative Breast Cancer and Other Primary Human Tumor Types Toward precision medicine in glioblastoma: the promise and the challenges Triple-negative breast cancer: present challenges and new perspectives

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