About: PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects

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About: PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects Goto Sponge NotDistinct Permalink

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scientific article published on 09 January 2002

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в березні 2002 (uk) article scientifique publié en janvier 2002 (fr) im März 2002 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 2002 (ast) scientific article published on 09 January 2002 (en)
publication date	wds:Q64379300-BEFDAB09-98E0-4AAD-8D00-890216690B11
publication date	2002-01-09 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q64379300-AB144A9D-0482-4D92-AE1B-D5F75B2B0AF4
language of work or name	English
cites work	wds:Q64379300-0AF7CFE1-6552-49B5-A836-5B34AD71DEF8 wds:Q64379300-1E10680D-F186-42E7-A5DF-73D8D89A9077 wds:Q64379300-267FC00C-45FA-43C3-B796-74666D052057 wds:Q64379300-286282A0-FC64-459C-B9FD-CADF1DE8BB37 wds:Q64379300-34766406-A0EE-4EC7-AA88-002F2B3EED66 wds:Q64379300-36A4D2E5-75EC-4A67-8C90-CBFEBDFDA118 wds:Q64379300-3BF10D32-B5DC-4C25-A4F4-1FF9B0115BDF wds:Q64379300-4B5A2CFD-39A7-49FD-9290-600F63FA1476 wds:Q64379300-5A3E06C7-8CE6-485A-B355-4351BC620AFB wds:Q64379300-5AD2D8FD-825A-4571-B0ED-DF6D76AFFB0E wds:Q64379300-5CC41338-D005-4CBB-B286-6F03BC9C84E1 wds:Q64379300-69CF0463-80F0-4913-A89C-FD046ECF79F4 wds:Q64379300-79C60EAA-70DF-433D-988F-F6202038B8CE wds:Q64379300-7BD4EDE3-EA16-4583-9170-943ACBBBFA97 wds:Q64379300-7DBE4F24-8A99-49C4-8EBE-DB852DB5B71C wds:Q64379300-835D59BC-31C1-428F-9892-B21D8142C6B4 wds:Q64379300-9110FEC3-775E-4C7E-A9B9-CA49BB891B12 wds:Q64379300-927B260C-509C-47D2-88E0-D823D0AEC9AB wds:Q64379300-95F77289-33CB-44BF-83D1-2C56C085FD60 wds:Q64379300-96544A2C-90D4-4AC1-8943-A6C5142E5154 wds:Q64379300-A3BFE98A-D3C1-45BC-99E3-36628FDCB09B wds:Q64379300-A673919D-99F9-4D6B-9056-A74C62C401F7 wds:Q64379300-A98224C2-8FD5-42F0-9DCD-0B96C673E71E wds:Q64379300-AA0D4F58-E798-40F7-99D4-AA72A6448A11 wds:Q64379300-AAB0BB62-6605-4462-AFBD-F228811D31C7 wds:Q64379300-B15AD722-0A85-4C89-8B0B-A6BD2B35B4D7 wds:Q64379300-B5913B43-A4B8-432D-AC37-B67D477A090E wds:Q64379300-BE3570F0-CC8A-43AC-ACB3-7A4E478D2553 wds:Q64379300-C7DB99F2-3F08-4281-8D12-56D0821E4696 wds:Q64379300-C9735318-72A9-48C7-A0A7-6D70407F28B5 wds:Q64379300-CE75E8D3-FD4F-451F-853E-DC571B4AD644 wds:Q64379300-D4A251B5-F62F-4EB1-AB97-3611051BC89F wds:Q64379300-E02D51A4-0E24-4FDF-9967-A5DE537CA4CB wds:Q64379300-E0390455-8702-4027-B9E7-58C350CE0109 wds:Q64379300-E23DAF83-6A43-49C9-B80C-331949DADCB3 wds:Q64379300-E56A53E2-4CD3-448D-9A64-847710936974 wds:Q64379300-F0770964-3D4F-4523-ACD3-B62DA1A52118 wds:Q64379300-F6A12301-77EE-45AD-9BDF-9C8219C13D7B wds:Q64379300-FAA0B665-8FDF-4A28-AEA4-CDF759470595
cites work	Maintenance of vascular endothelial cell-specific properties after immortalization with an amphotrophic replication-deficient retrovirus containing human papilloma virus 16 E6/E7 DNA. Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells HCPTPA, a protein tyrosine phosphatase that regulates vascular endothelial growth factor receptor-mediated signal transduction and biological activity. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt Permanent cell line expressing human factor VIII-related antigen established by hybridization Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer Signalling through the lipid products of phosphoinositide-3-OH kinase The role of phosphoinositide 3-kinase lipid products in cell function Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain The biology of vascular endothelial growth factor Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN A simplified system for generating recombinant adenoviruses Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation Insulin-mediated stimulation of protein kinase Akt: A potent survival signaling cascade for endothelial cells Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway Endothelial cell apoptosis in capillary network remodeling. Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation Inactivation of the PTEN tumor suppressor gene is associated with increased angiogenesis in clinically localized prostate carcinoma Endothelial cell-matrix interactions: in vitro models of angiogenesis The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways Isolation and characterization of an established endothelial cell line from transgenic mouse hemangiomas PTEN controls tumor-induced angiogenesis Adenoviral gene transfer of nitric oxide synthase: high level expression in human vascular cells Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes
author name string	wds:Q64379300-8C86E7FD-F803-4E54-8512-5B88945057EA
author name string	Jianhua Huang
rdfs:label	PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects (en) PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects (nl)
skos:prefLabel	PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects (en) PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects (nl)
name	PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects (en) PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects (nl)
author	wds:Q64379300-9AE9CCC3-3966-40FA-90E4-38520734B158
author	Christopher D. Kontos
title	wds:Q64379300-7FAEB6CD-7D99-43AA-892F-CD211A9CAFCB

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