About: Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific article published on 08 February 2019

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) im Februar 2019 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en febreru de 2019 (ast) наукова стаття, опублікована в лютому 2019 (uk) scientific article published on 08 February 2019 (en)
publication date	wds:Q64265985-8873F0B9-AFE1-4B1F-8211-469F6D9111DE
publication date	2019-02-08 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q64265985-8246D06A-29A8-475F-ADF9-802F929DD5F3
language of work or name	English
cites work	wds:Q64265985-01D16371-8E7A-424C-818E-1482C394F32E wds:Q64265985-1B6099E7-F0CB-4B6A-A118-E1E0116EB1F1 wds:Q64265985-382536A5-4A55-4ECC-96CC-57094E4593FC wds:Q64265985-54B593FD-66C9-4A70-B55D-319AED5137A1 wds:Q64265985-5DE05924-0ED1-4008-87C5-0D1A3789280D wds:Q64265985-A2543DF6-62E3-4777-9026-79E100E4A00F wds:Q64265985-A5DC28B6-B522-457A-BA2E-3217D0AA9155 wds:Q64265985-B1E336CC-B5EB-44C0-A9A1-B1D3F476DF12 wds:Q64265985-BC5738BE-0B76-48C9-9CC2-BFCECF1DC0F9 wds:Q64265985-D84C9A2B-3549-42B2-B0F6-394F2D85957A wds:Q64265985-E649A34F-C9A0-46C0-AE30-A803DA9C3211 wds:Q64265985-EDF69060-FED3-4B6F-8152-6FFC9A7029D8
cites work	Moving beyond rules: the development of a central nervous system multiparameter optimization (CNS MPO) approach to enable alignment of druglike properties Clinical development success rates for investigational drugs Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition Kinases as druggable targets in trypanosomatid protozoan parasites Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing. Repurposing strategies for tropical disease drug discovery Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasis Establishment of a structure-activity relationship of 1H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery. The thermodynamic basis for the use of lipophilic efficiency (LipE) in enthalpic optimizations Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery
author name string	wds:Q64265985-55A92F68-AB55-4FDE-B894-6A8E39C08726 wds:Q64265985-671A4F13-5C1B-463F-8C59-F63CE7585C9A wds:Q64265985-9EE2A077-336E-4FEB-8B70-1C68100654BB wds:Q64265985-AE10AA67-5C14-4AFB-B1C0-8BF86B0E21B4 wds:Q64265985-D29EA3F4-E208-48D7-A657-E21B34B8485C wds:Q64265985-E7229FB6-065C-44AF-8BB5-F8EF9932F797 wds:Q64265985-FC7FB6E2-AF94-4D90-A471-E4F7F99DBC6C
author name string	Conor R Caffrey Francisco Gamarro Pilar Manzano Raquel García-Hernández Dolores González-Pacanowska María S Martínez-Martínez Luis Miguel Ruiz-Pérez
rdfs:label	Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents (en) Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents (nl)
skos:prefLabel	Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents (en) Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents (nl)
name	Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents (en) Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents (nl)
author	wds:Q64265985-0437DE67-0174-4E06-82B1-8B960EF48BA8 wds:Q64265985-196E7552-351E-470D-AAAB-A57CD67C39C5 wds:Q64265985-71299B66-04A1-4193-8714-6A84FAAA9499 wds:Q64265985-8C6D91C2-1C0E-4251-A3D6-CDBCD7AE5D11 wds:Q64265985-AD7B6443-A67A-44F7-A922-3E51BDE1A960 wds:Q64265985-BDF1275D-FEA2-4E70-9699-C73FD83821CD wds:Q64265985-CA7CD92D-B5BD-4F77-8422-F4CC0C8BEBA2 wds:Q64265985-EA0E3EA2-3C9A-457B-8A2F-8E1F3644DD28 wds:Q64265985-F874608B-AD61-4F59-A491-7EA0031FD5AF
author	Michael P. Pollastri Domingo I Rojas-Barros Miguel Navarro Rosario Díaz González Lori Ferrins Gloria Ceballos-Pérez Veronica Gomez-Pérez Guiomar Pérez-Moreno Dana M Klug
title	wds:Q64265985-3FA30F51-F758-4725-9760-F48179107701
title	Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents (en)
page(s)	wds:Q64265985-8B4C0025-39FB-44C0-8C1C-158CBE84A6B4
page(s)	e0007129
instance of	wds:Q64265985-B2B9E9D7-DC6D-44AC-89EE-74591AAE8C2C
instance of	scholarly article
main subject	wds:Q64265985-2F2286B8-9E2F-4DF8-B7BE-1699DEEEDC90 wds:Q64265985-71D59FE3-72E1-4821-BF90-8D38D093C1A6
main subject	African trypanosomiasis infectious disease
PubMed ID	wds:Q64265985-F2BC958C-E4ED-49B3-A0BA-4986371B9DED
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30735501
PubMed ID	30735501
published in	wds:Q64265985-B84FEA6D-B23E-44A9-B780-782AA5594EE2
published in	PLoS Neglected Tropical Diseases
issue	wds:Q64265985-0915C3F6-2523-4FBD-AEAE-BB731B1372FF
volume	wds:Q64265985-EADFF82A-8257-45D8-842F-3175B6D857B6
issue	2
volume	13
DOI	wds:Q64265985-57CE8B1B-0446-4CF4-AEE7-31CFCD298BA0
DOI	http://dx.doi.org/10.1371/JOURNAL.PNTD.0007129
DOI	10.1371/JOURNAL.PNTD.0007129
copyright license	wds:Q64265985-bbcf064c-769c-4d29-89b4-39ad3f08d4a1
copyright status	wds:Q64265985-0b51d033-f551-4dd0-a435-e96bdbfdd44c
copyright license	Creative Commons Attribution 4.0 International
copyright status	copyrighted
PMCID	wds:Q64265985-57CA7438-784D-41D5-B751-661CCC6C8B99
PMCID	6383948

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 180 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software