About: In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)--(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry

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About: In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)--(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry Goto Sponge NotDistinct Permalink

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scientific article published on 25 February 2019

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2019 (fr) im Februar 2019 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en febreru de 2019 (ast) наукова стаття, опублікована в лютому 2019 (uk) scientific article published on 25 February 2019 (en)
publication date	wds:Q64106117-8A1D0B37-8A95-4927-9052-A90B14FB6CBB
publication date	2019-02-25 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q64106117-3E709ED8-A547-41AF-A972-FB121D09AE92
language of work or name	English
cites work	wds:Q64106117-1355DA7D-8512-4BCD-B3F7-93D19A38D382 wds:Q64106117-2C26DB17-4765-4AF7-81B3-3DB56C3ED1DB wds:Q64106117-2CF00921-9105-484A-B011-8146BE00BBFE wds:Q64106117-3681A69A-F644-4CBE-AC21-F8D637CB35EF wds:Q64106117-745F84CB-FEBE-4032-BC5C-BE6E82709BDC wds:Q64106117-82737151-688D-4682-B91A-3656817B116C wds:Q64106117-9506295D-4029-4E15-B7CC-FCE4049B39FF wds:Q64106117-97973A24-300A-4817-A45C-B6D842848DD9 wds:Q64106117-9B570704-07FA-4869-B6CF-F78FE6654745 wds:Q64106117-A40318B9-A1BA-4018-9811-5FA644150052 wds:Q64106117-AAEC08FE-138F-42BB-96C9-A48DC6203D61 wds:Q64106117-B3F84617-F24E-477E-AC0C-7BCAD62E9644 wds:Q64106117-B6091C6E-6759-448C-8A94-2491CAF3D678 wds:Q64106117-B741F9D4-A014-4777-AFB5-0C7AB4F883E1 wds:Q64106117-B8830D6A-7D7D-4711-BD3C-EEBF93825206 wds:Q64106117-BC6219B8-96C0-4F7D-BACA-C93E9CBCCD4F wds:Q64106117-C7D07D1A-3C05-4F4B-863D-BBA5429C88A2 wds:Q64106117-D7FEADDE-7590-43DE-86E9-C0AFE9F1CA50 wds:Q64106117-DC00A5C9-2F57-4179-884A-9B956BC42D46 wds:Q64106117-E0310305-4B7B-4DF8-A89A-5039CB734BBC wds:Q64106117-E21F08BE-0457-4969-94B1-052AD5CCEC8C wds:Q64106117-E7787122-732D-49F3-A4AE-AC6D36535632 wds:Q64106117-FC5202AC-5699-4ED5-AD60-F8104C4C2772 wds:Q64106117-FF0E6579-8D1F-495F-B689-92802CDB3C9E
cites work	Molecular interaction of serotonin 5-HT2A receptor residues Phe339(6.51) and Phe340(6.52) with superpotent N-benzyl phenethylamine agonists Differences in potency and efficacy of a series of phenylisopropylamine/phenylethylamine pairs at 5-HT(2A) and 5-HT(2C) receptors Effects of the hallucinogen 2,5-dimethoxy-4-iodophenethylamine (2C-I) and superpotent N-benzyl derivatives on the head twitch response Physiological parameters in laboratory animals and humans Metabolism of designer drugs of abuse: an updated review. Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists. Two cases of severe intoxication associated with analytically confirmed use of the novel psychoactive substances 25B-NBOMe and 25C-NBOMe Determination of 4-bromo-2,5-dimethoxy-N-[(2-methoxyphenyl)methyl]-benzeneethanamine (25B-NBOMe) in serum and urine by high performance liquid chromatography with tandem mass spectrometry in a case of severe intoxication Metabolic fate and detectability of the new psychoactive substances 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25B-NBOMe) and 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25C-NBOMe) in human and Metabolic pathways of 4-bromo-2,5-dimethoxyphenethylamine (2C-B): analysis of phase I metabolism with hepatocytes of six species including human In vitro characterization of potential CYP- and UGT-derived metabolites of the psychoactive drug 25B-NBOMe using LC-high resolution MS. 25C-NBOMe and 25I-NBOMe metabolite studies in human hepatocytes, in vivo mouse and human urine with high-resolution mass spectrometry Case series: toxicity from 25B-NBOMe--a cluster of N-bomb cases. Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH. In vitro metabolism of a novel synthetic cannabinoid, EAM-2201, in human liver microsomes and human recombinant cytochrome P450s 4-Bromo-2,5-dimethoxyphenethylamine (2C-B) and structurally related phenylethylamines are potent 5-HT2A receptor antagonists in Xenopus laevis oocytes Studies on the metabolism and toxicological detection of the new psychoactive designer drug 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe) in human and rat urine using GC-MS, LC-MS(n), and LC-HR-MS/MS Metabolic Fate of Hallucinogenic NBOMes. Comparative metabolism of honokiol in mouse, rat, dog, monkey, and human hepatocytes Targeted and non-targeted metabolite identification of MAM-2201 in human, mouse, and rat hepatocytes. The NBOMe series: a novel, dangerous group of hallucinogenic drugs Synthetic cannabinoids are substrates and inhibitors of multiple drug-metabolizing enzymes Analysis of 4-bromo-2,5-dimethoxyphenethylamine abuser's urine: identification and quantitation of urinary metabolites Identification of monoamine oxidase and cytochrome P450 isoenzymes involved in the deamination of phenethylamine-derived designer drugs (2C-series)
author name string	wds:Q64106117-27CC572F-C3A3-4B2F-82B4-95F4C7DFB047 wds:Q64106117-32F1466F-A894-4C27-92E5-AB0FB13BB34A wds:Q64106117-49943FBA-FE59-4C3A-B25D-A37862270717 wds:Q64106117-80281083-9F26-4FF9-8B69-0E1F4C81BC12 wds:Q64106117-AECA51DD-F995-4E60-A776-41FD108CA138
author name string	Yong-Yeon Cho Joo Young Lee Ju-Hyun Kim Jaesin Lee Sangwhan In
rdfs:label	In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)--(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry (en) In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)--(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry (nl)
skos:prefLabel	In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)--(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry (en) In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)--(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry (nl)
name	In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)--(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry (en) In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)--(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry (nl)
author	wds:Q64106117-81BC99CB-75B8-4EBC-92BF-F03F5720987C wds:Q64106117-B3D08861-9DA3-441C-93BA-877304EE2890 wds:Q64106117-C739FC50-B139-42CE-A18B-83A5C9161373
author	Hye Suk Lee Han Chang Kang Sun Joo Kim
title	wds:Q64106117-06FE3295-2E1A-4613-B9CF-042F3EA9AE3F
title	In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)-N-(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry (en)
page(s)	wds:Q64106117-5D530DE8-8266-4E6B-80A2-CA1E111304BC
page(s)	818
instance of	wds:Q64106117-5F73375C-DDFF-47C4-8595-E32B9E5F1D86
instance of	scholarly article
main subject	wds:Q64106117-3D0C44FF-3731-4818-B252-FA16C036D935
main subject	CYP
PubMed ID	wds:Q64106117-5AEBF50B-1672-47FE-A5D0-61459B1E2E03
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30823561
PubMed ID	30823561
published in	wds:Q64106117-1EF66731-BEA6-4EB5-857E-FFC397BA2BE0
published in	Molecules
issue	wds:Q64106117-BD0959B4-C2D4-4C3C-B579-B4E7FB89C10E
volume	wds:Q64106117-851A7575-88A1-47AC-8607-F06A3E59F91F
issue	4
volume	24
DOI	wds:Q64106117-8228018B-C409-43E3-9D4E-6D3204FA193B
DOI	http://dx.doi.org/10.3390/MOLECULES24040818

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