About: Hydroxychloroquine reverses the prothrombotic state in a mouse model of antiphospholipid syndrome: Role of reduced inflammation and endothelial dysfunction

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About: Hydroxychloroquine reverses the prothrombotic state in a mouse model of antiphospholipid syndrome: Role of reduced inflammation and endothelial dysfunction Goto Sponge NotDistinct Permalink

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scientific article published on 14 March 2019

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в березні 2019 (uk) im März 2019 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en marzu de 2019 (ast) scientific article published on 14 March 2019 (en)
publication date	wds:Q64095376-67401960-1B43-4871-A6D0-DA27C4403CFD
publication date	2019-03-14 00:00:00Z (xsd:dateTime)
cites work	wds:Q64095376-02530F25-7304-4AD4-88E1-3225F2792405 wds:Q64095376-02589A0E-098F-4BDB-B956-178460166B01 wds:Q64095376-0DD5EC83-DAEC-4A07-AB30-C1FC73716158 wds:Q64095376-1057BBA8-20DE-4B80-96D9-FA77CA416184 wds:Q64095376-176C0393-1E7A-4109-AB6A-ECE7CD16E0B9 wds:Q64095376-2710033A-73CE-4D39-8FC0-F81147A01AF2 wds:Q64095376-2F5E3CA6-9AAB-4102-BF35-32103169E522 wds:Q64095376-36ACA56C-0A3B-48FF-BEF4-E4065E5278DE wds:Q64095376-62992B66-6935-4BAB-91B8-8AC7AE11EA84 wds:Q64095376-6535E936-F57F-4CD5-82FF-3E8D3B014E77 wds:Q64095376-874ED18C-3A2A-4C6A-9BB3-1B2D36FC2F55 wds:Q64095376-87D0E535-497C-4BFB-8E7C-B09B97B1BED5 wds:Q64095376-8A523BAB-CFDA-446D-9840-758D80438563 wds:Q64095376-95335DCD-3F32-48E0-889E-729AD4596E69 wds:Q64095376-97674D8F-A615-427D-8B02-C1432DC705F6 wds:Q64095376-98C6755B-CD50-4AC9-A98C-8F63A137C280 wds:Q64095376-9AC66B8F-2038-4E88-B492-EE293AF6A0E7 wds:Q64095376-9BB42780-77B4-4B79-8345-600C2E837DF0 wds:Q64095376-A7924235-C121-44AE-8C89-7B2905FB11EF wds:Q64095376-B2D0F0D4-99A9-4DA5-9866-9779F8D0F85D wds:Q64095376-B3912391-97CB-483C-990F-32A7538F203A wds:Q64095376-B6EE79F8-B147-432C-8D20-43D75DFE7E95 wds:Q64095376-B75A0F9D-C6F9-4FD3-8318-F6E9B1D0BFD8 wds:Q64095376-B773D78E-F51C-4432-8181-E1CAB589A731 wds:Q64095376-B8E7A596-ED25-4976-BC0F-321888031407 wds:Q64095376-B96F0E6F-1912-4BA8-B476-0337A5D7CD71 wds:Q64095376-BDEF5442-8673-4053-A0D8-8DC29E4F3F6E wds:Q64095376-C1843BF9-A692-4A47-9F19-05ADE061D4DB wds:Q64095376-C20A5DE0-8D29-40D4-B303-9A8B6AF98646 wds:Q64095376-CC1586ED-181C-4F02-B738-5BB7E04CE772 wds:Q64095376-D298DA63-BA2F-4369-A283-B7CB5F6E8F08 wds:Q64095376-DB336C75-A6ED-4216-BCD8-275E9AB15859 wds:Q64095376-DDF96F6F-1F34-400D-8460-3EDB39D93D88 wds:Q64095376-E43C7204-2221-4F5C-BC75-E0136E40029F wds:Q64095376-EDC84273-C75A-4A5E-A929-CC83F7E7C5B3 wds:Q64095376-EF103BA5-84A2-4091-B7AE-EB3DD5ADC7D9 wds:Q64095376-EFA97FFF-9925-4B53-9C48-A010510B3273 wds:Q64095376-F7539479-E891-46FC-BBAC-DBA9C312FBFF
cites work	Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice Vascular Abnormalities, Paraoxonase Activity, and Dysfunctional HDL in Primary Antiphospholipid Syndrome Thrombin generation testing in routine clinical practice: are we there yet? International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS) Increased soluble vascular cell adhesion molecule 1 concentrations in patients with primary or systemic lupus erythematosus-related antiphospholipid syndrome: Correlations with the severity of thrombosis Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo Thrombin generation, a function test of the haemostatic-thrombotic system Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies. The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome. Antithrombotic effects of hydroxychloroquine in primary antiphospholipid syndrome patients Role of Toll-like receptors 2 and 4 in mediating endothelial dysfunction and arterial remodeling in primary arterial antiphospholipid syndrome. Thrombosis in primary antiphospholipid syndrome: a pivotal role for monocyte tissue factor expression Characterization of monocyte tissue factor activity induced by IgG antiphospholipid antibodies and inhibition by dilazep Effects of human monoclonal anticardiolipin antibodies on platelet function and on tissue factor expression on monocytes. Increased levels of tissue factor mRNA in mononuclear blood cells of patients with primary antiphospholipid syndrome Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drug Hydroxychloroquine reverses platelet activation induced by human IgG antiphospholipid antibodies. Hypercoagulable state in patients with antiphospholipid syndrome is related to high induced tissue factor expression on monocytes and to low free protein s. Interaction of inflammation, thrombosis, aspirin and enoxaparin in CNS experimental antiphospholipid syndrome Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2. Patient-derived monoclonal antibodies directed towards beta2 glycoprotein-1 display lupus anticoagulant activity Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-kappaB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK- Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial Tissue factor in the antiphospholipid syndrome The effect of hydroxychloroquine on haemostasis, complement, inflammation and angiogenesis in patients with antiphospholipid antibodies Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium. Endosomal NADPH-oxidase is critical for induction of the tissue factor gene in monocytes and endothelial cells. Lessons from the antiphospholipid syndrome Thrombinography shows acquired resistance to activated protein C in patients with lupus anticoagulants Thrombin generation and factor X assays for the assessment of warfarin anticoagulation in thrombotic antiphospholipid syndrome. Hydroxychloroquine inhibits proinflammatory signalling pathways by targeting endosomal NADPH oxidase Impaired brachial endothelial function in patients with primary anti-phospholipid syndrome Antiphospholipid antibody-induced cellular responses depend on epitope specificity : implications for treatment of antiphospholipid syndrome. Infliximab improves endothelial dysfunction in a mouse model of antiphospholipid syndrome: Role of reduced oxidative stress Prothrombotic Effect of Anti-beta-2 Glycoprotein-1 Antibodies on the Expression of Tissue Factor, Thrombomodulin, and Plasminogen Activator Inhibitor-1 in Endothelial Cells IL-2, IL-6 and TNF levels in primary antiphospholipid syndrome Development of a thrombin generation test in cultured endothelial cells: Evaluation of the prothrombotic effects of antiphospholipid antibodies Attenuation of antimalarial agent hydroxychloroquine on TNF-α-induced endothelial inflammation
author name string	wds:Q64095376-2311DE72-9E8C-48CF-9FB1-240A671BDA73 wds:Q64095376-234C925A-6EFD-4097-9BFD-CB40D0948D59 wds:Q64095376-340D450D-98DC-4478-BDA4-50E0CFCFD858 wds:Q64095376-4F516DE8-DF91-4824-9208-4FDE61E52880 wds:Q64095376-60E6AA8B-8523-4E21-858F-EBBCDBEC4EB4 wds:Q64095376-6413AC2D-7197-4BFD-8338-C955B189075D wds:Q64095376-8A259D07-4D0B-4DAF-AB1E-7FF81546CA52 wds:Q64095376-E85DA2DE-AA17-43CA-8BE1-EFAB84D11BAD wds:Q64095376-EF600905-FD0E-4DA5-9B9C-23BF13CB2B66 wds:Q64095376-F61D32B1-852F-40DB-BB68-5AB0EE10B0EC wds:Q64095376-F7B9C9C4-4C67-476C-A09D-662A94D41E3E wds:Q64095376-F97FFC59-D9FA-4654-817F-A1C34BB6297E
author name string	Vincent Richard Robinson Joannides Ludovic Galas Fabienne Jouen

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