About: Multitarget therapeutic strategies for Alzheimer's disease

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Multitarget therapeutic strategies for Alzheimer's disease Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scholarly article by Mostafa M Ibrahim & Moustafa T Gabr published March 2019 in Neural Regeneration Research

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в березні 2019 (uk) im März 2019 veröffentlichter wissenschaftlicher Artikel (de) scholarly article by Mostafa M Ibrahim & Moustafa T Gabr published March 2019 in Neural Regeneration Research (en)
publication date	wds:Q64082907-ED75A049-29D4-425E-A11A-9DA16CBBF248
publication date	2019-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q64082907-9195F548-4A1F-413E-9F3D-36AA48DE5ABE
language of work or name	English
cites work	wds:Q64082907-07AE2D4F-003D-4E11-96FC-A8C7F586315E wds:Q64082907-0BC1930B-AA97-4239-8C4A-8B0C319C5BAC wds:Q64082907-6018F272-3A47-42D1-A4E9-20CBFCC09CD0 wds:Q64082907-62231264-B500-45AD-8C61-2E7E1DFD5D68 wds:Q64082907-64A242D6-50B2-4C53-A1F5-7826991691D6 wds:Q64082907-725F23B4-B0E8-4241-800F-E3A4D9B23D60 wds:Q64082907-7CCB499F-1193-44C2-BD1E-27D4B2F85377 wds:Q64082907-7E6CE8C8-FD07-4C01-87C7-917BE51F71D4 wds:Q64082907-808B6B85-AC60-42FE-AB10-66428B55287F wds:Q64082907-8B909ABB-01E8-4FB4-926E-0ADB9F521FC9 wds:Q64082907-9D44CA3C-EF86-4DCB-B833-74E8D0231D53 wds:Q64082907-9EFDE798-8E3E-48D7-ADDB-AB6B745FEF48 wds:Q64082907-AC0D898E-1151-4E68-93C6-A33404D8E3E0 wds:Q64082907-B453EDD8-8EE7-4046-802E-9CA7CCCF79C7 wds:Q64082907-B9D33CA7-980F-480E-A3BB-B9F9E5E0D423 wds:Q64082907-C0BB9B51-5AC8-4FB3-89B9-FA511E122118 wds:Q64082907-C2E936B3-5C99-46F8-B5A1-3A27F3F33892 wds:Q64082907-CFE818C2-1495-4529-AA46-8C19309FD776 wds:Q64082907-E57DE6C5-A948-4D5B-AB47-1C8CD8CDF271 wds:Q64082907-E6845FC8-A15B-4931-9F83-A1A3214DD211 wds:Q64082907-E71D09F7-4AA7-471E-BF84-81E0C3F9C7CA wds:Q64082907-EC4DA38D-EDA5-41A6-B70E-BC48D18D7511 wds:Q64082907-F3C3F461-3C44-45A7-A2C3-8DA67AF041F4 wds:Q64082907-FAD9BDFD-9FF2-4E30-917E-9E43D3F8F33B wds:Q64082907-FBCD7AAE-1BED-420A-91E6-A6B43358F377
cites work	Neurotoxicity of amyloid β-protein: synaptic and network dysfunction Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds. Neuroprotection by curcumin in ischemic brain injury involves the Akt/Nrf2 pathway Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation Neuroprotection by the multitarget iron chelator M30 on age-related alterations in mice. Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors Discovery of Novel Pyrazolopyrimidinone Derivatives as Phosphodiesterase 9A Inhibitors Capable of Inhibiting Butyrylcholinesterase for Treatment of Alzheimer's Disease. Neurotoxicity and synaptic plasticity impairment of N-acetylglucosamine polymers: implications for Alzheimer's disease. The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels Tacrine-Natural-Product Hybrids for Alzheimer's Disease Therapy. Novel Tacrine-Hydroxyphenylbenzimidazole hybrids as potential multitarget drug candidates for Alzheimer's disease. Heterocyclic compounds as key structures for the interaction with old and new targets in Alzheimer's disease therapy. Design, Synthesis, and Evaluation of Donepezil-Like Compounds as AChE and BACE-1 Inhibitors Dual GSK-3β/AChE Inhibitors as a New Strategy for Multitargeting Anti-Alzheimer's Disease Drug Discovery. Dual BACE-1/GSK-3β Inhibitors To Combat Alzheimer's Disease: A Focus Review. BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease. Tacrine-propargylamine derivatives with improved acetylcholinesterase inhibitory activity and lower hepatotoxicity as a potential lead compound for the treatment of Alzheimer's disease. Synthesis, biological activity, and biopharmaceutical characterization of tacrine dimers as acetylcholinesterase inhibitors Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease. Novel multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease. Design and synthesis of donepezil analogues as dual AChE and BACE-1 inhibitors Dual functional cholinesterase and MAO inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of homoisoflavonoid derivatives
author name string	wds:Q64082907-04163A2A-88A6-4223-AFA3-6119C2D0F6F3 wds:Q64082907-F0A21E7B-EE1A-4100-8661-125F1C6D99FD
author name string	Moustafa T Gabr Mostafa M Ibrahim
rdfs:label	Multitarget therapeutic strategies for Alzheimer's disease (en) Multitarget therapeutic strategies for Alzheimer's disease (nl)
skos:prefLabel	Multitarget therapeutic strategies for Alzheimer's disease (en) Multitarget therapeutic strategies for Alzheimer's disease (nl)
name	Multitarget therapeutic strategies for Alzheimer's disease (en) Multitarget therapeutic strategies for Alzheimer's disease (nl)
title	wds:Q64082907-E6CEFEB5-5DF6-4FE8-BF8A-C257B6685A2E
title	Multitarget therapeutic strategies for Alzheimer's disease (en)
page(s)	wds:Q64082907-112ADA38-D641-4118-BFE7-4C783E2DA117
page(s)	437-440
instance of	wds:Q64082907-8CAAFBB5-F9DC-4459-88E5-B87539FD4456
instance of	scholarly article
main subject	wds:Q64082907-19AE52ED-2B19-4034-81AD-DC86863DD549 wds:Q64082907-4BD5E6D4-EF99-4175-A9AF-B7DDD3F05E69 wds:Q64082907-9BB0C2A5-2EEA-44CD-B400-F406F22C1C4B wds:Q64082907-EB1098C2-E942-4746-B0D5-522025184E33
main subject	Alzheimer's disease hybridization wd:Q421076 acetylcholinesterase
PubMed ID	wds:Q64082907-3980C2AE-0170-4543-83DC-B790D49EE224
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30539809
PubMed ID	30539809
published in	wds:Q64082907-DFB9F42C-7940-4954-922A-34C7B125883A
published in	Neural Regeneration Research
issue	wds:Q64082907-D7C1F3FF-59E5-44B1-A6E0-BC5ABD3D138D
volume	wds:Q64082907-323F8E4C-AC45-4A36-8A2B-925066DDE12D
issue	3
volume	14
DOI	wds:Q64082907-FF262A28-B1F9-4FE6-9AF6-5B7AEC489F80
DOI	http://dx.doi.org/10.4103/1673-5374.245463
DOI	10.4103/1673-5374.245463
PMCID	wds:Q64082907-79DADD60-D7CD-436B-9721-81B4234892CC
PMCID	6334608
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q64082907
is cites work of	A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease. Synthesis and AChE-Inhibitory Activity of New Benzimidazole Derivatives

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 183 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software