About: Selective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death

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About: Selective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death Goto Sponge NotDistinct Permalink

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scientific article published on 02 December 2004

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2004 (fr) наукова стаття, опублікована в грудні 2004 (uk) im Dezember 2004 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 2004 (ast) scientific article published on 02 December 2004 (en)
publication date	wds:Q63383605-95E48104-B834-4C84-8958-7131AED43993
publication date	2004-12-02 00:00:00Z (xsd:dateTime)
author name string	wds:Q63383605-07BFAE25-192E-4748-A69D-A3266C7379A1 wds:Q63383605-1C6D1BB5-AF81-4F89-A59A-FA7F4A916545 wds:Q63383605-9FB032C5-4A1B-4A9E-8054-EB8F467965D6 wds:Q63383605-A2E0E590-11D9-4D42-A391-3CB3E40654AD wds:Q63383605-C414062E-3C34-4160-9CB9-70D66E174C5D wds:Q63383605-D4AE8402-FF19-4519-807F-46AADA712E9F
author name string	Roderick T Bronson David Housman Alain Charest Joseph H McCarty John Savill Denise Crowley
rdfs:label	Selective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death (en) Selective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death (nl)
skos:prefLabel	Selective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death (en) Selective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death (nl)
name	Selective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death (en) Selective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death (nl)
author	wds:Q63383605-24359DC8-B0E7-4472-AF9C-1F98EEA609BC wds:Q63383605-4A8BDA21-7634-4ACB-9FAD-0D2A668786C2 wds:Q63383605-FFCCDF9C-2757-4A55-A742-2B61C9C3B2C7
author	Richard Hynes Jürgen Roes Adam Lacy-Hulbert
title	wds:Q63383605-9835FBA6-E0F8-4335-8579-6B9909768439
title	Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death (en)
page(s)	wds:Q63383605-ECD4C624-EF68-4905-8A93-F46C59234A0F
page(s)	165-176
instance of	wds:Q63383605-D0DF3181-259F-4229-AE88-DEA0AB79FA02
instance of	scholarly article
main subject	wds:Q63383605-536B9024-9526-4A15-A703-FEF61FEC0E90
main subject	nervous system
PubMed ID	wds:Q63383605-25CCFD33-8019-4033-8C63-59FB5CD8DB9B
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15576410
PubMed ID	15576410
published in	wds:Q63383605-CA6EED57-BE5F-4857-8226-7CDCA8C63C8D
published in	Development
issue	wds:Q63383605-A9643F7A-418D-4063-A184-6F79957B32E4
volume	wds:Q63383605-E2F54404-3C71-43BA-A927-AE78CD9DFF03
issue	1
volume	132
number of pages	wds:Q63383605-11589671-609E-4680-8727-D0F9236926EF
number of pages	12 (xsd:decimal)
DOI	wds:Q63383605-BFB9BCF4-0F03-49A8-B0C8-39D5F923B59F
DOI	http://dx.doi.org/10.1242/DEV.01551
DOI	10.1242/DEV.01551
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q63383605
is cites work of	Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions βPix plays a dual role in cerebral vascular stability and angiogenesis, and interacts with integrin αvβ8. Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor. Neurovascular development: The beginning of a beautiful friendship Developmental angiogenesis of the central nervous system Gene-environment interactions in severe intraventricular hemorrhage of preterm neonates Glia unglued: how signals from the extracellular matrix regulate the development of myelinating glia Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124. Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage αV integrins in angiogenesis and cancer A betaPix Pak2a signaling pathway regulates cerebral vascular stability in zebrafish. Netrin-1-alpha3beta1 integrin interactions regulate the migration of interneurons through the cortical marginal zone. Guiding neuronal cell migrations Integrin alphaV is necessary for gastrulation movements that regulate vertebrate body asymmetry Lessons from the embryonic neural stem cell niche for neural lineage differentiation of pluripotent stem cells Integrins as receptor targets for neurological disorders The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs Mice that lack activity of alphavbeta6- and alphavbeta8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice An interaction between {alpha}v{beta}8 integrin and Band 4.1B via a highly conserved region of the Band 4.1 C-terminal domain Beta1 integrins in radial glia but not in migrating neurons are essential for the formation of cell layers in the cerebral cortex. Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins Cell proliferation and interleukin-6-type cytokine signaling are implicated by gene expression responses in early optic nerve head injury in rat glaucoma Neuron-glial interactions in blood-brain barrier formation. Extracellular matrix and the neural stem cell niche Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders Integrins in angiogenesis and lymphangiogenesis Preferential expression of integrin αvβ8 promotes generation of regulatory T cells by mouse CD103+ dendritic cells. Inducible Cre recombinase activity in mouse mature astrocytes and adult neural precursor cells Temporal and spatial regulation of alpha6 integrin expression during the development of the cochlear-vestibular ganglion. Genetic approaches to study glial cells in the rodent brain. Phagocytosis of apoptotic cells in homeostasis Loss of cerebral cavernous malformation 3 (Ccm3) in neuroglia leads to CCM and vascular pathology Targeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances TGF-β signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular development Integrative mechanisms of oriented neuronal migration in the developing brain Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development Neuronal expression of the Ccm2 gene in a new mouse model of cerebral cavernous malformations. Mesangial cell integrin αvβ8 provides glomerular endothelial cell cytoprotection by sequestering TGF-β and regulating PECAM-1 Vascular development of the brain requires beta8 integrin expression in the neuroepithelium Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke Integrin-mediated regulation of neurovascular development, physiology and disease Beta8 integrin regulates neurogenesis and neurovascular homeostasis in the adult brain

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